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Degreasing and hair-growing preparation for preventing and treating seborrheic alopecia and preparation method thereof

A technology of seborrheic alopecia and dried ginger, applied to medical preparations containing active ingredients, pharmaceutical formulas, plant raw materials, etc., can solve problems such as emotional disorders, easy recurrence, mild liver function abnormalities, etc., and achieve high safety , exact curative effect, good synergistic effect

Active Publication Date: 2011-06-08
霸王(广州)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the process of realizing the present invention, the inventors found that there are at least the following problems in the prior art: adverse reactions using existing methods include mild abnormal liver function, sexual dysfunction, moderate to severe depression, emotional disturbance, abnormal sleep and eating habits, etc. , easy to relapse after drug withdrawal, difficult to maintain curative effect

Method used

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  • Degreasing and hair-growing preparation for preventing and treating seborrheic alopecia and preparation method thereof
  • Degreasing and hair-growing preparation for preventing and treating seborrheic alopecia and preparation method thereof
  • Degreasing and hair-growing preparation for preventing and treating seborrheic alopecia and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] Weigh raw materials (g) according to the following weights:

[0043] Dried ginger 30g, Chuanjiao 30g, Chuanxiong 20g, safflower 20g, Vitex 10g, Fangfeng 10g, Scutellaria baicalensis 10g, Angelica 10g.

[0044] The preparation method of lotion of the present invention:

[0045]Take 30g of dried ginger, 30g of Chuanjiao, 20g of Chuanxiong, 20g of safflower, 10g of Vitex, 10g of Fangfeng, 10g of Scutellaria baicalensis, and 10g of Angelica sinensis, add 70% ethanol to soak for 30min, then heat and reflux for 3 hours, and the temperature is controlled at 80°C. Keep the extract slightly boiling. Filter at room temperature, let it stand for 12 hours, take the supernatant and centrifuge for 20 minutes, add water to 1400ml, adjust the pH to 6.5-7.5 with citric acid, filter, add 0.15g of methylparaben and 0.15g of propylparaben, and the washed agent.

Embodiment 2

[0047] Weigh raw materials (g) according to the following weights:

[0048] Dried ginger 10g, Chuanjiao 40g, Chuanxiong 10g, safflower 40g, Vitex 5g, Fangfeng 30g, Scutellaria baicalensis 5g, Angelica 40g.

[0049] The preparation of ointment of the present invention:

[0050] Take 10g of dried ginger, 40g of Chuanjiao, 10g of Chuanxiong, 40g of safflower, 5g of Vitex, 30g of Fangfeng, 5g of Scutellaria baicalensis, and 40g of Angelica sinensis, add 70% ethanol to soak for 40min, and then heat and reflux for extraction for 2.5 hours. The temperature is controlled at 85°C. Keep the extract slightly boiling. Filter at room temperature, let it stand for 12 hours, take the supernatant and centrifuge for 15 minutes, concentrate to a relative density of 1.20, add 200 g of lanolin, 100 g of petrolatum, and 1 g of ethyl hydroxybenzoate, and mix well to obtain an ointment.

Embodiment 3

[0052] Weigh raw materials (g) according to the following weights:

[0053] Dried ginger 40g, Chuanjiao 10g, Chuanxiong 40g, safflower 10g, Vitex 30g, Fangfeng 5g, Scutellaria baicalensis 30g, Angelica 10g.

[0054] The preparation of oil agent of the present invention:

[0055] Take 40g of dried ginger, 10g of Chuanjiao, 40g of Chuanxiong, 10g of safflower, 30g of Vitex, 5g of Fangfeng, 30g of Scutellaria baicalensis, and 10g of Angelica sinensis, add 70% ethanol to soak for 20min, then heat and reflux for extraction for 3.5 hours, the temperature is controlled at 75°C, Keep the extract slightly boiling. Filter at room temperature, let stand for 10 hours, take the supernatant and centrifuge for 25 minutes, dissolve in an appropriate amount of hot glycerin, stir constantly, add glycerin to 1400ml, and mix well to obtain the oil.

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Abstract

The invention discloses a degreasing and hair-growing preparation for preventing and treating seborrheic alopecia, which is prepared from the following active pharmaceutical ingredients in parts by weight: 1-50 parts of dried ginger, 1-50 parts of pericarpium zanthoxyli, 1-50 parts of hemlock parsley, 1-50 parts of safflower, 1-50 parts of chastetree fruit, 1-50 parts of radix sileris, 1-50 parts of Baikal skullcap root and 1-50 parts of angelica. The preparation method comprises the following steps: soaking the active pharmaceutical ingredients in 70% ethanol for 20-40 minutes, and extracting by heating under reflux for 2.5-3.5 hours while controlling the temperature at 75-85 DEG C; keeping the extracting solution in a slight boiling state, filtering at normal temperature, standing for 10-12 hours, and centrifugalizing the supernatant for 15-25 minutes; and adding auxiliary materials or excipient to prepare into various preparation formulations for external use. The traditional Chinese medicine degreasing and hair-growing preparation can promote hair to grow and prevent and treat seborrheic alopecia, and has the advantages of clear curative effect and high safety.

Description

technical field [0001] The invention relates to a traditional Chinese medicine prescription, in particular to a fat-removing and hair-growing prescription for preventing and treating seborrheic alopecia and a preparation method thereof. Background technique [0002] According to the statistics of authoritative organizations, the proportion of men aged 25 to 35 in China is as high as 40%, and the total number has exceeded 150 million; hair loss is showing a younger trend, and 84.8% have been diagnosed as seborrheic alopecia. [0003] U.S. FDA (Food and Drug Administration, Food and Drug Administration) approved the only 5a-reductase inhibitor-Propecia (finasteride) for the clinical treatment of this disease, which can reduce serum and hair follicle DHT levels. [0004] In the process of realizing the present invention, the inventors found that the prior art has at least the following problems: adverse reactions using the existing methods include mild abnormal liver function, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P17/14
Inventor 陈啟源万玉华赖小平张榕文李耿刘丹丹
Owner 霸王(广州)有限公司
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