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Chinese medicinal preparation for treating diabetes and preparation method thereof

A technology of traditional Chinese medicine preparations and diabetes, which is applied in the field of Coptis rhizome oral preparations and its preparation, can solve the problems of not many preparations, and achieve the effects of convenient medication, stable reproducibility, and easy control of reactions

Inactive Publication Date: 2011-05-11
TIANJIN PACIFIC PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most of the reported content about Coptis chinensis is combined with other Chinese medicinal materials to make Coptis chinensis health products, such as Coptis chinensis health tea, Coptis chinensis health drink, etc. There are not many preparations made from a single component of Coptis chinensis, especially Coptidis rhizome chewable tablet made from single ingredient of Coptis chinensis has not been reported in the literature

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034]Dried 700 grams of Coptis chinensis, decocted in 8000ml of water (subject to soaked Coptis chinensis) for 2 hours, decocted in 5000ml of water for 2 hours, decocted in 5000ml of water for 2 hours, concentrated to a specific gravity of 1.25, and centrifuged at a high speed; the centrifuged supernatant was passed through Macroporous resin such as AB-8 type resin, eluted with water until there is no polysaccharide component, concentrated eluent, made 65% alcohol precipitation, placed in the refrigerator for 4hrs, filtered, and the filter cake was washed with absolute ethanol; vacuum dried, crushed and sieved or Spray-dry to obtain 110 grams of yellow or yellow-brown fine powder extract for subsequent use. 100 grams of dried Coptis chinensis, after 200-mesh ultrafine pulverization, 60 grams of Coptis chinensis powder is obtained for later use.

Embodiment 2

[0036] 110 grams of fine powdered Coptis chinensis extract, 100 grams of sorbitol, 40 grams of citric acid, 5 grams of aspartame, 350 grams of starch, 80 grams of dextrin, 60 grams of Coptidis superfine powder, and 10 grams of magnesium stearate. 220 tablets.

Embodiment 3

[0038] Fine powdered Coptidis extract 10g, sorbitol 18g, citric acid 0.9g, aspartame 0.5g, starch 57.6g, dextrin 14.4g, Coptidis superfine powder 7.2g, magnesium stearate 1.5g, made 20 tablets.

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Abstract

The invention discloses a Chinese medicinal preparation for treating diabetes, which is prepared by the following steps of: extracting 1 to 100 parts of golden thread to obtain fine powder extract which contains golden thread polysaccharides, mixing the extract and 0.1 to 80 parts of pharmaceutical excipient, granulating, adding 0.1 to 30 parts of dried golden thread superfine powder, and pressing into tablets. The golden thread chewable tablets avoid side effects produced when patients with the diabetes take western medicines for a long time, are conveniently taken by the patients, improve the compliance of the patients, and are easily accepted by the patients, and particularly the advantages of the tablets are better reflected under the conditions of going out, traveling and the like.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine preparations, and relates to an oral preparation of Coptidis Rhizoma with hypoglycemic effect and a preparation method thereof. Background technique [0002] Diabetes is divided into type 1 diabetes, type 2 diabetes and gestational diabetes. Among them, type 1 diabetes mostly occurs in adolescents, whose insulin secretion is insufficient, and must rely on insulin therapy to maintain life. Type 2 diabetes is more common in middle-aged and elderly people after the age of 30. The secretion of insulin is not low or even high. The main cause is that the body is not sensitive to insulin (insulin resistance). Gestational diabetes is caused by insulin resistance in cells, but insulin resistance is caused by hormones (hormones) secreted by pregnant women. Gestational diabetes usually resolves on its own after delivery. Insulin is the only hypoglycemic hormone in the body secreted by the β cel...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/718A61P3/10A61K125/00
Inventor 宋德成
Owner TIANJIN PACIFIC PHARMA
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