Equipment system for industrially producing Grignard reagent by using gaseous halogenated hydrocarbon

Abstract

The invention discloses an equipment system for industrially producing a Grignard reagent by using gaseous halogenated hydrocarbon, comprising a raw material feeding system and two reaction kettles, wherein a shell of each reaction kettle is provided with an observation window and a pressure gage; each reaction kettle is internally provided with a mixing propeller; a tetrahydrofuran or ether storage and absorption tank and a gaseous halogenated hydrocarbon pressure storage tank in the raw material feeding system are respectively connected with the two reaction kettles through a three-way valve; a magnesium feeding cabin is independently connected with the reaction kettles through a rapidly opened flange; and the two reaction kettles are same in structure and are connected in series through two gas-guide tubes. The two serially connected reaction kettles are adopted in the invention, the reaction in the two reaction kettles are simultaneously carried out, gaseous halogenated hydrocarbon is introduced to one of the reaction kettles, and unreacted halogenated hydrocarbon enters the other reaction kettle for continuous reaction to realize the reaction under the pressure near the normal pressure and the recovery of the halogenated hydrocarbon, thereby realizing the clean production of the Grignard reagent.

Description

technical field [0001] The invention belongs to the technical field of industrial application of Grignard reaction. Specifically, it relates to an equipment system for industrially producing Grignard reagents with gaseous halogenated hydrocarbons. Background technique [0002] The principle of Grignard Reaction has long been known to everyone involved in organic chemistry, and there are many literatures using its principle for various organic synthesis applications. Initiation and heat dissipation are the key links in the industrial synthesis of Grignard reagents from gaseous halogenated hydrocarbons. The method proposed in Chinese patent 200510025651.7 is to first prepare a small amount of Grignard reagent in the laboratory, and then add it to the reaction kettle to initiate the reaction; Chinese patent 200410051433.6 proposes to use ultrasonic waves to initiate the reaction; Chinese patent 200610127730.3 proposes to initiate the reaction by microwave radiation. The above...

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Problems solved by technology

U.S. Dow Corning Company has adopted in patent 03816950.9 to add excessive halogenated hydrocarbons to realize the relative reaction of magnesium is complete, the shortcoming of this method is also obvious: the recovery of unnecessary halogenated hydrocarbons will inevitably increase the investment in separation and recovery equipment

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