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Scar repair material

A technology for repairing materials and scars, applied in medical science, surgery, etc., can solve problems such as incomplete skin epidermis, no bacteria killing or inhibiting effect on the surface of scars, small cracks and infections that are not easy to detect with the naked eye, and achieve a good repairing effect , reduce the ratio, inhibit the secretion of the effect

Inactive Publication Date: 2011-04-13
TIANJIN JIASHITANG SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this type of product has the following disadvantages: a, passively seals moisture, does not have the function of actively moisturizing scarred skin, and passively repairs scars by hydrating scarred skin, rather than actively promoting the change of scarred skin structure; b, silicon The gel seals the scar skin from external bacterial infection, but does not actively kill or inhibit the bacteria on the surface of the scar; c, the skin epidermis on the surface of the scar body (scar or keloid after burn) is actually incomplete, and it is likely There are small cracks and infections that are not easy to detect with the naked eye, and simple silicone gel preparations cannot repair these small inflammations; d. It has no clear direct effect on inhibiting fibroblasts and collagen fibers in the scar body

Method used

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Effect test

Embodiment 1

[0022] A kind of scar repairing material, is made by following method: 1 mass part of N-carboxymethyl chitosan with a substitution degree of 60% is dissolved in 60 parts of water under stirring, and polyoxyethylene dehydrated by emulsification is added. 2 parts of sorbitol monolaurate, 5 parts of humectant glycerin, get transparent gel-like solution; Under homogenization, 40 parts of polydimethylsiloxane with a viscosity of 40000 are added to the gel-like solution, mixed Evenly, a kind of scar repair material can be obtained.

Embodiment 2

[0024] A kind of scar repairing material, is made with following method: 4 mass parts of N-carboxymethyl chitosan that substitution degree is 90% is dissolved in 80 parts of water under stirring, adds polyoxyethylene dehydration that plays emulsifying effect 2 parts of sorbitol monolaurate, 8 parts of humectant glycerin, get transparent gel-like solution; 50 parts of polydimethylsiloxane that viscosity is 100000 under homogeneous join in the described gel-like solution, Mix evenly to obtain a scar repair material.

Embodiment 3

[0026] A kind of scar repairing material, is made by following method: 0.5 mass part of N-carboxymethyl chitosan of degree of substitution 80% is dissolved in 10 parts of water under stirring, adds the polyoxyethylene sorrel that plays emulsifying effect 1 part of alcohol monolaurate, 10 parts of moisturizing agent glycerin to obtain a transparent gel-like solution; under homogenization, add 20 parts of polydimethylsiloxane with a viscosity of 80,000 to the gel-like solution, and mix well , to obtain a scar repair material.

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Abstract

The invention discloses a scar repair material which is prepared by the following method: dissolving 0.5-5 parts by weight of water-soluble chitosan or chitosan the deacetylation degree of which is 75-97% into 10-100 parts by weight of water or an acetic acid aqueous solution the mass concentration of which is 1-5% while stirring; adding 1-3 parts by weight of polyoxyethylene Sorbitan lauric acid monoester which has emulsifying action and 5-10 parts by weight of humectant glycerol to obtain a transparent gelatinous solution; adding 20-90 parts by weight of polydimethylsiloxane into the gelatinous solution under homogeneity; and evenly mixing to obtain the scar repair material. The scar repair material disclosed in the invention can actively and passively moisturize skin, has the efficacy on actively resisting and inhibiting bacteria, has the action on quickening the healing of skin wound surface, has better repair and protection actions on tiny flaws and infection on the scar surface as being used on the scar surface, and can inhibit the secretion of collagen type I in cheloid skin so as to lower the ratio of collagen type I / collagen type III.

Description

technical field [0001] The invention relates to a medical biological material, in particular to a scar repair material. Background technique [0002] Most of the scar treatment products currently on the market are single-component silicone scar repair stickers or silicone gel scar repair creams made of polysiloxane. The principle of such products for scar repair is to seal the skin with silicone , Form a breathable and impermeable protective film, prevent the moisture in the scar from dissipating, and form hydration with the skin to repair the scar. However, this type of product has the following disadvantages: a, passively seals moisture, does not have the function of actively moisturizing scarred skin, and passively repairs scars by hydrating scarred skin, rather than actively promoting the change of scarred skin structure; b, silicon The gel seals the scar skin from external bacterial infection, but does not actively kill or inhibit the bacteria on the surface of the sca...

Claims

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Application Information

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IPC IPC(8): A61L31/06A61L31/04
Inventor 王倩丁利营
Owner TIANJIN JIASHITANG SCI & TECH
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