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Thalictrum foeniculaceum bunge extract and use thereof in preparing drug for treating insomnia

A technology of taffia serrata and extract, which is applied in the field of plant extract and its preparation, can solve the problem that taffia serrata is not recognized by people and the like, and achieves the effects of low pharmaceutical cost, convenient preparation and easy availability of raw materials

Inactive Publication Date: 2011-04-13
王德记 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For a long time, Siye Tangsongcao has not been recognized by people, and it has been used as feed for cattle and sheep in large quantities and has not been developed and utilized as a Chinese herbal medicine.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Dry the silk-leaved pine grass at 30°C-60°C at low temperature, crush it and decoct it with water at a ratio of 1:10, decoct 2-3 times, each time for 1-3 hours, combine the extracts and pass through a 30-40 mesh sieve Filtrate, concentrate under reduced pressure at 40°C to 60°C to obtain a clear paste, the concentration of which is 7.8mg / ml, dry the obtained clear paste, grind it into a fine powder, and obtain the extract.

[0025] The obtained extract is added to starch, fully mixed, granulated, dried, granulated, and compressed into 50 mg tablets.

Embodiment 2

[0027] 1) Dry the silk-leaved pine grass at 30 ℃ ~ 60 ℃ at low temperature, crush it and decoct it with water at a ratio of 1:10, decoct 2 to 3 times, each time for 1 to 3 hours, combine the extracts and dry them for 30 to 40 minutes. Filter through a mesh sieve, concentrate under reduced pressure at 40° C. to 60° C. to become a clear paste; 2) carry out ethanol purification treatment on the obtained clear paste, and add concentration of 90% to 95% ethanol to the clear paste under stirring to make the clear paste The alcohol content in the mixture reaches 75%, let stand for 24 to 72 hours, take the supernatant and filter it through a 40 to 60 mesh sieve, concentrate under reduced pressure at 30°C to 50°C, and obtain a purified clear paste with a concentration of 6.9mg / ml , the purified clear paste is distilled under reduced pressure at 40°C to 60°C to remove ethanol; 3) cooling to room temperature, drying, grinding into fine powder to obtain the extract.

[0028] The obtained ...

Embodiment 3

[0030] 1) Dry the silk-leaved pine grass at 30 ℃ ~ 60 ℃ at low temperature, crush it and decoct it with water at a ratio of 1:10, decoct 2 to 3 times, each time for 1 to 3 hours, combine the extracts and dry them for 30 to 40 minutes. Filter through a mesh sieve, concentrate under reduced pressure at 40° C. to 60° C. to become a clear paste; 2) carry out ethanol purification treatment on the obtained clear paste, and add concentration of 90% to 95% ethanol to the clear paste under stirring to make the clear paste The alcohol content in the mixture reaches 70%, let it stand for 24-58 hours, take the supernatant and filter it through a 40-60 mesh sieve, concentrate under reduced pressure at 30°C-50°C, and distill it under reduced pressure at 40°C-60°C Ethanol; 3) under agitation again, add the ethanol that concentration is 90%~95% to make the alcohol content in the mixture to 85% in the described clear paste, leave standstill for 36~72 hours, take the supernatant and pass through...

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PUM

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Abstract

The invention relates to a plant extract, a preparation method and use thereof, in particular to a thalictrum foeniculaceum bunge extract, and use and a preparation method thereof in preparing a drug for treating insomnia. The extract is prepared by taking thalictrum foeniculaceum bunge as a raw material and performing direct pulping extraction, water extraction and ethanol purification or ethanol extraction. The thalictrum foeniculaceum bunge extract has the advantages of available raw materials, low pharmaceutical cost, less consumption, obvious treatment effect on insomnia symptoms, no obvious adverse reaction shown in clinical trials and obvious common effect on intermittent insomnia and patients suffering from insomnia for more than 10 days, and is convenient in preparation.

Description

technical field [0001] The invention relates to a plant extract and its preparation method and use, in particular to a silk leaf tang pine extract and its use and preparation method in the preparation of insomnia medicine. Background technique [0002] Tangsongcao belongs to the Ranunculaceae plant, which is a unique medicinal plant in my country. It generally has anti-cancer, antibacterial and anti-inflammatory, anti-virus, blood pressure-lowering, heat-clearing and detoxifying, and analgesic effects. Currently, the recorded Tangsongcao has more than 60 species. species, mainly concentrated in the southwest region. Silk leaf Tangsongcao (Thalictrum foeniculaceum Bunge) is a special species of Tangsongcao, which was included in "Flora of China" in 2010. According to the investigation, this variety has rich wild resources and strong vitality, which is convenient for artificial large-scale planting and cultivation . For a long time, Siye Tangsongcao has not been recognized by...

Claims

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Application Information

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IPC IPC(8): A61K36/71A23L1/30A61P25/20A23L33/105
Inventor 王德记王光峰
Owner 王德记
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