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Washing-free hand disinfectant and preparation method

A disinfectant and hand-used technology, applied in medical preparations with non-active ingredients, medical preparations containing active ingredients, liquid delivery, etc., can solve problems such as skin irritation, injury to doctors and nurses, rough skin, etc., to prevent Effects of cross-infection, simple preparation method, and convenient use

Inactive Publication Date: 2010-12-15
JIANGSU AITEFU 84
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the long-term use analysis found that there are many problems in detergents and disinfectants such as irritation, rough skin, chapped skin, rashes and other allergic problems after long-term use. Grease and fungicides cause skin irritation, especially for medical workers, who need to use disinfectant detergent frequently and for a long time, and such adverse consequences often occur
In recent years, with the continuous development of synthesis technology, the emergence of many new mild surfactants and bactericidal compounds has created certain conditions for the improvement of detergents and disinfectants in reducing irritation. Many bactericidal activities have good affinity with the human body. Better products have been developed, and after a period of use, it has been found that skin rashes and allergies have indeed shown a downward trend, but the occurrence of the above phenomena has not been completely avoided. Therefore, for professionals who wash their hands frequently and need to be disinfected, it is best to use this type of disinfection washing Disinfectant is a contradictory issue after all. According to statistics from authoritative organizations such as HICPAC, CDCH and APIC in the United States, a nurse in a hospital in the United States has to wash his hands about 120 times in one shift on average. The use of conventional hand washing and disinfectants will definitely cause harm to doctors and nurses.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The components are taken according to the following mass percentages: 0.05% triclosan, 5.0% ethanol, 0.5% propylene glycol, 0.4% glycerol, 1.0% hydroxypropyl methylcellulose, 0.05% disodium edetate, essence 0.02%, deionized water 92.98%.

[0025] Prepare the disinfectant according to the following steps: (1), add the ethanol of the formula ratio into the reactor, and add 1 / 2 of the deionized water of the formula quantity, then add the EDTA-2Na of the formula quantity and stir until completely dissolved; ( 2), while stirring, slowly add the formula amount of hydroxypropyl methylcellulose, stir and heat up to 50 to ℃, so that the hydroxypropyl methylcellulose is completely dissolved and becomes a transparent gel-like colloid; (3), stirring Add the propylene glycol and glycerin of formula quantity successively under the state to stir completely evenly; (4), add the triclosan of formula quantity while stirring, fully dissolve and cool to 30 ℃; (5), add the remaining amount ...

Embodiment 2

[0027] The preparation method of this disinfectant is the same as in Example 1, wherein the mass percent of each component is as follows: Triclosan 0.2%, ethanol 20.0%, propylene glycol 1.0%, glycerol 1.0%, hydroxypropyl methylcellulose 3.0%, EDTA disodium 0.08%, essence 0.05%, deionized water 74.67%.

Embodiment 3

[0029] The preparation method of this disinfectant is the same as in Example 1, wherein the mass percent of each component is as follows: Triclosan 0.6%, ethanol 35.0%, propylene glycol 3.5%, glycerol 2.0%, hydroxypropyl methylcellulose 5.5%, Disodium edetate 0.19%, essence 0.375%, deionized water 52.835%.

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PUM

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Abstract

The invention discloses washing-free hand disinfectant and a preparation method. In the invention, triclosan serving as a main active ingredient and ethanol, propylene glycol, glycerol, hydroxypropyl methyl cellulose (HPMC), ethylene diamine tetraacetic acid (EDTA-2Na) and the like are mixed in a certain ratio to prepare hydrogel washing-free hand disinfectant. The gel product can be carried conveniently and does not overflow like other common liquid products. The washing-free hand disinfectant is mainly used for cleaning and disinfecting hand and is particularly used by medical personnel for disinfecting hands and preventing crossed infection with pathogenic bacteria.

Description

technical field [0001] The invention relates to a disinfectant and a preparation method, in particular to a hand-use disposable disinfectant and a preparation method. Background technique [0002] In daily life, people often use soap and scented soap as hygienic cleaning products, which can wash and remove most of the dirt and bacteria on the surface of human skin and hands, and effectively prevent and reduce the occurrence of infectious diseases to a certain extent. As early as 1846, the British Lgnaz Semmelweis found through a lot of observation and practice that the treatment of heavily polluted hands with antibacterial agents was more effective in preventing disease infection than treatment with ordinary soap. On this basis, people have developed washing products such as phenol soap and chlorophenol liquid disinfection detergents with medicinal functions, such as Dettol series, 84 series, organic iodine series, etc., so that these products are not only widely used in peo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K31/085A61K47/38A61P31/00A61K31/045
Inventor 赵建洲
Owner JIANGSU AITEFU 84
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