Medicine composition for treating hyperuricemia and related diseases and preparation method and application thereof

A kind of technology of hyperuricemia and composition, applied in the field of pharmaceutical composition, can solve the problems such as not much, increase of blood uric acid medicine, etc.

Active Publication Date: 2010-09-15
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Traditional Chinese medicine believes that gout is mainly caused by overeating sorghum, dampness, turbidity and poison, exogenous wind and cold, poor Qi and blood, spleen and kidney disorders, dampness, phlegm, blood stasis, and heat block the meridians. , mostly adopt the treatment principles of clearing away heat and detoxification, promoting dampness to relieve turbidity, dredging wind and dredging collaterals, promoting blood circulation and removing blood stasis, reducing swelling and relieving pain, invigorating the spleen and nourishing the kidney. , Fufang Shenjin Capsules, Tongfengding Tablets, Tongfengshu Capsules and Granules, Tongfengding Capsules, Binhuo Tongfeng Mixture, etc., cannot meet the sharply rising market demand for anti-gout Chinese patent medicines that can effectively reduce blood uric acid, and the incubation period of gout is high Drugs for the treatment of uric acidemia are still blank

Method used

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  • Medicine composition for treating hyperuricemia and related diseases and preparation method and application thereof
  • Medicine composition for treating hyperuricemia and related diseases and preparation method and application thereof
  • Medicine composition for treating hyperuricemia and related diseases and preparation method and application thereof

Examples

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Effect test

Embodiment 1

[0155] Example 1. A pharmaceutical composition for treating hyperuricemia and diseases related to hyperuricemia (such as gout, uric acid nephropathy), which is made of the following traditional Chinese medicine raw materials in weight ratio, Liu Jinu 15; Qin Pi 15; Zhejiang Fritillaria 15; wild chrysanthemum 30. The preparation method is: extract the active ingredients of each raw material according to the conventional technology, add conventional auxiliary materials, and make oral or external preparations.

Embodiment 2

[0156] Example 2. A pharmaceutical composition for treating hyperuricemia and diseases related to hyperuricemia (such as gout, uric acid nephropathy), which is made of the following traditional Chinese medicine raw materials in the following weight ratios: Liu Jinu 0.1; Qinpi 0.1; Zhejiang Fritillaria 0.1; wild chrysanthemum 0.1. The preparation method is as follows: taking all the raw materials of the traditional Chinese medicine according to the weight ratio, decocting in water to obtain a water extract; concentrating the water extract to make a mixture or an oral liquid.

Embodiment 3

[0157] Example 3. A pharmaceutical composition for treating hyperuricemia and diseases related to hyperuricemia (such as gout, uric acid nephropathy), which is made of the following traditional Chinese medicine raw materials in weight ratio, Liu Jinu 9; Qin Pi 9; Zhejiang Fritillaria 3; wild chrysanthemum 15. The preparation method is as follows: extract the volatile oil from wild chrysanthemum and Liu Jinu according to the weight ratio; combine the dregs and the remaining raw materials of traditional Chinese medicine to decoct in water to obtain a water extract; add volatile oil to the water extract after concentration to make a mixture or oral liquid .

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Abstract

The invention relates to a medicine composition for treating hyperuricemia and hyperuricemia related diseases (such as gout, urate nephropathy). The medicine composition is characterized by being prepared by adopting the following traditional Chinese medicine raw material according to the weight proportion: 0.1-15g of artemisia anomala, 0.1-15g of the bark of ash, 0.1-15g of thunberg fritillary bulb, 0.1-30g of wild chrysanthemum flower, 0-30g of astragalus root, 0-15g of cassia twig, 0-15g of kadsura pepper stem, 0-15g of herba lycopi and 0-15g of baical skullcap root. The invention discloses a preparation method, a preparation and application of the medicine composition. The invention has better safety, can effectively lower the concentration of uric acid and remarkably improve the symptoms of all stages of gout, and is suitable for treatment of hyperuricemia related diseases (such as gout, urate nephropathy), especially treatment of gout incubation (hyperuricemia) and diapause.

Description

technical field [0001] The invention relates to a pharmaceutical composition using traditional Chinese medicine as a raw material, especially a pharmaceutical composition for treating hyperuricemia and diseases related to hyperuricemia (such as gout, uric acid nephropathy); the invention also relates to the drug Preparation method, formulation and use of the composition. Background technique [0002] Gout is a group of metabolic diseases caused by the disorder of purine metabolism, excessive production of uric acid and / or decreased excretion of uric acid, and continuous increase of blood uric acid level, resulting in the deposition of urate crystals in joints and soft tissues. [0003] The clinical manifestations of gout can be divided into four stages: latent stage (hyperuricemia stage), acute stage, intermittent stage, and chronic stage. The asymptomatic period only manifests as hyperuricemia without any symptoms. It usually takes several years to decades to develop from ...

Claims

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Application Information

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IPC IPC(8): A61K36/8966A61P19/06A61P13/12
Inventor 萧伟丁岗曹亮崔瑛杨保林李明慧陈俊
Owner JIANGSU KANION PHARMA CO LTD
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