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Drug combination for removing freckles and preparation method thereof

A composition and drug technology, applied in the direction of drug combination, pharmaceutical formula, drug delivery, etc., can solve the problems of rising cost and complicated steps, and achieve the effect of low cost, simple and convenient manufacturing process, and light color

Active Publication Date: 2010-09-08
GUIZHOU YIBAI PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, in the prior art, 15 kinds of traditional Chinese medicines such as Cortex Phellodendri, Bupleurum, Rhizoma Chuanxiong, Angelica, Prunella vulgaris, Duckweed, Radix Paeoniae Alba, Radix Scutellariae, Shell, Peach Kernel, Salvia Miltiorrhiza, Mulberry Leaf, Spatholobus Spatholobus, Safflower, and Angelica Dahurica were used to prepare Freckle-removing medicines use a wide variety of Chinese herbal medicines and the steps are complicated, resulting in increased costs

Method used

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  • Drug combination for removing freckles and preparation method thereof
  • Drug combination for removing freckles and preparation method thereof
  • Drug combination for removing freckles and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0101] Embodiment 1: the preparation of granule

[0102] (1) Take raw materials according to the following ratio:

[0103] Angelica 300g, safflower 270g, Angelica dahurica 210g, American ginseng 120g, vitamin C 30g, pearl powder 9g, aspartame 3g

[0104] (2) Grind angelica, safflower, angelica, and American ginseng into coarse powder, pass through a 50-mesh sieve, mix evenly, add 9000g of water to soak for 120 minutes, decoct and extract 3 times, each extraction time is 5 hours, the second The amount of water used for decocting for the first and third times is 10 times the weight of the medicinal material. Filter and collect the filtrate. The filtrate is concentrated to a relative density of 1.20 at 50°C. Add ethanol to make the alcohol content 50%, and place it for 48 hours to precipitate. filter.

[0105] (3) Take the supernatant, recover ethanol, and concentrate at 60°C to a relative density of 1.30, and dry the concentrate at 60°C until it is completely ready for use;

...

Embodiment 2

[0108] Embodiment 2: the preparation of tablet

[0109] (1) Take raw materials according to the following ratio:

[0110] Angelica 450g, safflower 405g, Angelica dahurica 315g, American ginseng 166g, vitamin C 40g, pearl powder 13g

[0111] (2) Crush the raw materials of angelica, safflower, angelica, and American ginseng into coarse powder, pass through a 60-mesh sieve, mix well, add 12300g of water and soak for 120 minutes, decoct and extract 3 times, each extraction time is 4 hours, the first The water consumption for the 2nd and 3rd decoction is 10 times the weight of the medicinal material, filter, collect the filtrate, concentrate the filtrate to a relative density of 1.30 at 60°C, add ethanol to make the alcohol content 80%, leave it for 48 hours, and precipitate ,filter.

[0112](3) Take the supernatant, recover ethanol, and concentrate at 70°C to a relative density of 1.30, and dry the concentrate at 40°C until it is completely ready for use;

[0113] (4) Sieve vit...

Embodiment 3

[0115] Embodiment 3: capsules

[0116] (1) Prepare raw materials according to the following ratio:

[0117] Angelica 150g, safflower 135g, Angelica dahurica 105g, American ginseng 60g, vitamin C 15g, pearl powder 4g.

[0118] (2) Grind the raw materials of angelica, safflower, angelica dahurica and American ginseng into coarse powder, pass through a 20-mesh sieve, mix well, add 7220g of water to soak for 60 minutes, decoct and extract twice, each extraction time is 3 hours, the second The water consumption for the 2nd and 3rd decoction is 5 times the weight of the medicinal material, filter, collect the filtrate, concentrate the filtrate to a relative density of 1.10 at 50°C, add ethanol to make the alcohol content 70%, leave it for 24 hours, and precipitate ,filter.

[0119] (3) Take the supernatant, recover ethanol, and concentrate at 40°C to a relative density of 1.10, and dry the concentrate at 40°C until it is completely ready for use;

[0120] (4) Sieve vitamin C and ...

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Abstract

The invention discloses a TCM (traditional Chinese medicine) preparation for removing freckles and a preparation method thereof. The TCM preparation comprises the following components: Chinese angelica, red flower, angelica root, American ginseng, vitamin C, pearl powder and auxiliary materials. The TCM preparation of the invention is mainly applicable in removing chloasma and other stains and improving the pigmentation. Compared with the prior art, the invention has the advantages of safe administration, exact curative effect, simple prescription and convenient preparation process. Therefore, the TCM preparation is suitable for industrialized mass-production.

Description

technical field [0001] The invention relates to a freckle-removing medicinal composition and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] Facial pigmentation is a clinically common symptom on the outer layer of the skin. It can occur in both men and women, especially in women, especially in married women. Uncertain, hindering the appearance of the face. Mainly divided into freckles, chloasma, skin melanosis and other pigmented lesions. There are many reasons for spots. Modern medicine believes that spots are closely related to pregnancy, endocrine disorders, mental stress, depression, and trauma. According to the theory of traditional Chinese medicine, the occurrence of color spots is closely related to the imbalance of yin and yang in the human body and the disharmony of qi and blood. [0003] The commonly used treatment methods generally include oral medicine, use of freckle-removing cosmetics, acup...

Claims

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Application Information

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IPC IPC(8): A61K36/286A61K9/16A61K9/48A61K9/20A61K9/00A61K9/30A61P17/00A61K31/375A61K35/56A61K35/618
Inventor 窦啟玲
Owner GUIZHOU YIBAI PHARMA CO LTD
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