Eureka AIR delivers breakthrough ideas for toughest innovation challenges, trusted by R&D personnel around the world.

Preparation method of compound antihypertensive preparation

A compound preparation and high blood pressure technology, applied in the field of medicine, can solve the problems of inaccurate clinical drug dosage, influence on drug efficacy, increase in side effects, etc., and achieve the effects of improving antihypertensive efficacy, fewer adverse reactions, and good antihypertensive effect.

Inactive Publication Date: 2010-06-30
JIANGSU JIBEIER PHARMA
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0016] The product of the present invention overcomes that when metoprolol and hydrochlorothiazide are used clinically, the drug dose is increased to ensure the curative effect when a single drug is used alone, resulting in a significant increase in side effects; Inaccurate use of clinical drug dosage, defects affecting the efficacy of drugs

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method of compound antihypertensive preparation
  • Preparation method of compound antihypertensive preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A compound preparation containing the following components:

[0034] Metoprolol 50mg

[0035] Hydrochlorothiazide 25mg

[0036] Starch 15mg

[0037] Calcium Sulfate 8mg

[0038] Talc 2mg

[0039] This embodiment can be made into compound metoprolol-hydrochlorothiazide tablet, and the preparation method can adopt the preparation method of common pharmaceutical preparations.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a compound preparation for treating hypertension, which comprises 10-100mg of metoprolol and 5-50mg of hydrochlorothiazide. The product of the invention overcomes the defect that a side effect is markedly enhanced caused by increasing the medicament dosage for ensuring the curative effect when the metoprolol and the hydrochlorothiazide are clinically used at present and one medicament is singly used, and provides a new compound preparation. The metoprolol and the hydrochlorothiazide are combined, and the curative effect has synergistic and complementary actions; the tolerance of patients is increased, the compliance is improved, the dosage is decreased, an adverse reaction is lightened, and the compound preparation is convenient to take and has low price.

Description

technical field [0001] The invention relates to the technical field of medicine, and discloses a preparation method of a compound antihypertensive preparation. Background technique [0002] Hypertension is a common cardiovascular disease and a major public health problem worldwide. my country currently has about 100 million hypertensive patients. According to the epidemiological survey in 1991, the awareness rate of hypertension in my country's urban and rural areas was 36% and 13%, and the treatment rate was 17% and 5%, respectively. The form of hypertension prevention and treatment is quite severe. According to the forecast of WTO, by 2020, non-communicable diseases will account for 79% of the causes of death in my country, among which cardiovascular diseases will take the first place. [0003] Commonly used drugs for the treatment of hypertension are the beta-blocker metoprolol and the diuretic hydrochlorothiazide. [0004] Metoprolol (Hydrochlorothiazide), the chemica...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/549A61K31/138A61P9/12
Inventor 吴修艮陈进高瑞银魏福荣朱月华
Owner JIANGSU JIBEIER PHARMA
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com