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Method for preparing antihypertensive preparation

A technology of high blood pressure and compound preparations, which is applied in the field of medicine, can solve the problems of inaccurate clinical dosage, influence of drug efficacy, and increase of side effects, and achieve the effect of improving antihypertensive efficacy, less adverse reactions, and good antihypertensive effect

Inactive Publication Date: 2010-06-30
JIANGSU JIBEIER PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] The product of the present invention overcomes that when felodipine and candesartan are used clinically, the dosage of the drug is increased to ensure the curative effect when the drug is used alone, resulting in a significant increase in side effects; , and the use of inaccurate clinical dosages affects the defects of drug efficacy

Method used

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  • Method for preparing antihypertensive preparation
  • Method for preparing antihypertensive preparation

Examples

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Embodiment 1

[0032] A compound preparation containing the following components:

[0033] Felodipine 10mg

[0034] Candesartan 8mg

[0035] Starch 30mg

[0036] Calcium Sulfate 1mg

[0037] Talc powder 1mg

[0038] This embodiment can be made into compound felodipine-candesartan tablet, and the preparation method can adopt the preparation method of common pharmaceutical preparations.

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Abstract

The invention discloses a complex preparation for curing hypertension. The preparation comprises 2.5 to 50mg of felodipine and 2 to 40mg of candesartan. The preparation overcomes the defect that obviously increased side effects caused by increasing the medicament dosage to ensure the curative effect in single medicament when the felodipine and the candesartan are used clinically, and provides the novel complex preparation. Combination of the felodipine and the candesartan has synergic and complementary curative effect. The complex preparation increases tolerance of patients, improves compliance, reduces dosage, lightens adverse reactions, is convenient for taking, and has low price.

Description

technical field [0001] The invention relates to the technical field of medicine, and discloses a preparation method of an antihypertensive preparation. Background technique [0002] Hypertension is the most common cardiovascular disease and a major public health problem worldwide. my country currently has about 100 million hypertensive patients. According to the epidemiological survey in 1991, the awareness rate of hypertension in my country's urban and rural areas was 36% and 13%, and the treatment rate was 17% and 5%, respectively. The form of hypertension prevention and treatment is quite severe. According to the forecast of WTO, by 2020, non-communicable diseases will account for 79% of the causes of death in my country, among which cardiovascular diseases will take the first place. [0003] Commonly used drugs for the treatment of hypertension include the calcium antagonist felodipine and the angiotensin receptor antagonist candesartan. [0004] Felodipine, the chemi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4422A61K31/4184A61P9/12
Inventor 吴修艮陈进高瑞银王慧沈华
Owner JIANGSU JIBEIER PHARMA
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