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Compound antihypertensive preparation

A compound preparation and high blood pressure technology, applied in the field of medicine, can solve the problems of affecting the curative effect of drugs, inaccurate clinical drug dosage, increased side effects, etc., and achieve the effects of improving the curative effect of blood pressure, less adverse reactions and good blood pressure effect.

Inactive Publication Date: 2010-06-30
JIANGSU JIBEIER PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0016] The product of the present invention overcomes that when felodipine and telmisartan are used clinically, the drug dose is increased to ensure the curative effect when a single drug is used alone, resulting in a significant increase in side effects; , and the use of inaccurate clinical dosages affects the defects of drug efficacy

Method used

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  • Compound antihypertensive preparation
  • Compound antihypertensive preparation

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Embodiment 1

[0033] A compound preparation containing the following components:

[0034] Felodipine 5mg

[0035] Telmisartan 80mg

[0036] Starch 10mg

[0037] Calcium sulfate 4mg

[0038] Talc 1mg

[0039] In this embodiment, the compound felodipine-telmisartan tablet can be made, and the preparation method can adopt the preparation method of ordinary pharmaceutical preparations.

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Abstract

The invention discloses a compound preparation for treating hypertension, which comprises 1-10mg of felodipine and 10-100mg of telmisartan. The product of the invention overcomes the defect that a side effect is markedly enhanced caused by increasing the medicament dosage for ensuring the curative effect when the felodipine and the telmisartan are clinically used at present and one medicament is singly used, and provides a new compound preparation. The felodipine and the telmisartan are combined, and the curative effect has synergistic and complementary actions; the tolerance of patients is increased, the compliance is improved, the dosage is decreased, an adverse reaction is lightened, and the compound preparation is convenient to take and has low price.

Description

Technical field [0001] The invention relates to the technical field of medicine and discloses a compound antihypertensive preparation. Background technique [0002] Hypertension is the most common cardiovascular disease and a major public health problem worldwide. There are currently about 100 million hypertensive patients in my country. The results of an epidemiological survey in 1991 showed that the awareness rate of hypertension in my country's urban and rural areas was 36% and 13%, and the treatment rate was 17% and 5%, respectively. The form of hypertension prevention and treatment is quite severe. According to WTO forecasts, non-communicable diseases will account for 79% of deaths in my country by 2020, and cardiovascular diseases will take the first place. [0003] Commonly used drugs for the treatment of hypertension are the calcium antagonist felodipine and the angiotensin receptor antagonist telmisartan. [0004] Felodipine (Felodipine), chemical name 4-(2,3-dichlorophen...

Claims

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Application Information

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IPC IPC(8): A61K31/4422A61K31/4184A61P9/12
Inventor 吴修艮陈进高瑞银魏福荣朱月华
Owner JIANGSU JIBEIER PHARMA
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