Coating technology of chlorophyll copper sodium tablet film

Abstract

The invention relates to the coating technology of a chlorophyll copper sodium tablet film, which is characterized in that the coating technique process of a film coat comprises the following steps of: properly and completely dissolving medicinal film coating powder to prepare 15 percent coating mixed suspension liquid to keep the temperature and store; placing a white tablet into a film coating pot at 40-50 DEG C; operating according to an operation program and setting a rotation speed to be 8-10rpm; starting a peristaltic pump when the white tablet is slightly heated; and adjusting the position of an adjusting spraying gun with a spraying speed of 5-8ml / min. The drying is carried out layer by layer, the surface color of the tablet is uniform and the tablet is discharged after blowing the cold air for 15-20 minutes. The tablet appearance quality, the weight difference, the disintegration time limitation and the like accord with quality standard requirement, thereby the coating time and the coating materials are saved.

Description

Technical field: [0001] This technology is used in the coating process of sodium copper chlorophyllin tablets to isolate air, avoid light, prevent moisture, and increase the stability of the drug. Background technique [0002] Sodium copper chlorophyllin tablet is an oral preparation processed from derivatives of chlorophyll (extracted from silkworm excrement). It is clinically used to treat leukopenia caused by various reasons, and can also be used for acute and chronic hepatitis, persistent hepatitis and Treatment of hepatomegaly and cirrhosis caused by hepatitis. At present, there are four pharmaceutical manufacturers in China producing this product, all of which are coated with sugar-coated tablets. [0003] Disadvantages of sugar-coated tablets: [0004] 1. The syrup coating process is based on sucrose, talcum powder, and gelatin, which are a variety of excipients that have nothing to do with drug treatment, and are added to the surface of the drug tablet core. Theref...

AI Technical Summary

Problems solved by technology

[0004] 1. The syrup coating process is based on sucrose, talcum powder, and gelatin, which are a variety of excipients that have nothing to do with drug treatment, and are added to the surface of the drug tablet core. Therefore, long-term use is not suitable for diabetic patients

[0005] 2. It is prone to splinters, flowers, mildew spots, disintegration overtime, content decline, strong hygroscopicity, and difficult to store

[0006] 3. Most of the operation process relies on the operator to control the coating quality by experience and feel, and there are many uncontrollable factors in the syrup coating process

[0008] 5. The coating time of sugar-coated tablets is longer, it takes 8-10 hours