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Corneal contact lens preserving liquid composition and preparation method thereof

A technology of corneal contact lens and composition, which is applied in the direction of chemical instruments and methods, other chemical processes, etc., can solve the problems of poor wettability of the lens, and achieve the effect of alleviating dryness

Active Publication Date: 2010-04-07
HAICHANG CONTACT LENSES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

And the contact lens preservation solution that adds as polyvinyl alcohol, polyvinylpyrrolidone, poloxamer, sodium hyaluronate in the commercially available product all has certain defect, and poloxamer is a tensio-active agent, can Quickly moves tear fluid away from the lens, resulting in poor lens wettability; sodium hyaluronate degrades when the lens is heat sterilized

Method used

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  • Corneal contact lens preserving liquid composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Trehalose 1%, lubricating and moisturizing agent: polyvinylpyrrolidone 0.003%, isotonicity regulator: sodium chloride 0.5%, buffering agent: boric acid 0.64%, borax 0.09%, pure water 97.76%.

Embodiment 2

[0020] Trehalose 2%, lubricating and moisturizing agent: polyvinyl alcohol 0.006%, isotonicity regulator: sodium chloride 0.83%, buffering agent: disodium hydrogen phosphate 0.17%, sodium dihydrogen phosphate 0.03%, pure water 96.96%.

Embodiment 3

[0022] Trehalose 2%, lubricating and moisturizing agent: poloxamer 0.5%, isotonicity regulator: potassium chloride 0.83%, buffering agent: disodium hydrogen phosphate 0.17%, sodium dihydrogen phosphate 0.03%, pure water 96.47%.

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PUM

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Abstract

The invention provides a corneal contact lens preserving liquid composition which is characterized by being composed of the following components in weight percent: 0.001-10% of mycose, 0.001-5% of lubricating moisturizing agent, 0.01-4% of isotonic regulator, 0.001-10% of buffering agent and 70-99.9% of pure water. The preparation method of the corneal contact lens preserving liquid composition is as follows: placing the above components into pure water in turn for dissolving; adjusting the pH value to a range of 6.5-7.8 with sodium hydroxide and hydrochloric acid, wherein the osmotic pressure is 280-320mosm / kg.H2O; and degerming and filtering the solution with 0.22mu m of degerming objects to obtain the product. The invention has the functions of preserving, lubricating and moisturizing the lens of corneal contact lens and can relieve the dryness of eyes.

Description

technical field [0001] The invention relates to a composition for preserving corneal contact lenses. Specifically, the composition is a corneal contact lens preservation liquid composition including trehalose and a preparation method thereof. Background technique [0002] Manufacturers of contact lenses usually pack contact lenses in glass bottles or blisters made of aluminum-plastic materials, and glass bottles and blisters made of aluminum-plastic materials add buffer solution as a preservation solution for contact lenses, because the lens material may self-adhesive Or stick to the packaging material, so the manufacturer adds surfactants or lubricants to the preservation solution, such as polyvinyl alcohol, polyvinylpyrrolidone, poloxamer, sodium hyaluronate, to reduce or eliminate lens self-adhesion or Adhesion to packaging materials. In addition, adding lubricating ingredients to the contact lens preservation solution can improve the discomfort when wearing the lens an...

Claims

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Application Information

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IPC IPC(8): C09K3/00
Inventor 何坚
Owner HAICHANG CONTACT LENSES
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