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Application of Chinese medicinal composition in preparation of medicament for treating rheumatic heart disease

A composition and technology of traditional Chinese medicine, applied in the field of Chinese herbal medicine, can solve problems such as the application of undisclosed pharmaceutical compositions, and achieve the effects of no drug dependence and tolerance, and no adverse reactions

Active Publication Date: 2010-02-24
HEBEI YILING MEDICINE INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The patent does not disclose the application of the pharmaceutical composition in the preparation of drugs for the treatment of rheumatic heart disease

Method used

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  • Application of Chinese medicinal composition in preparation of medicament for treating rheumatic heart disease

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] In order to facilitate the application of the Chinese medicine composition in the treatment of rheumatic heart disease, the Chinese medicine composition is prepared as a capsule

[0032] prescription:

[0033] Ginseng 89g Ophiopogon japonicus 112g Cornus officinalis 224g Salvia miltiorrhiza 224g

[0034] Fried Suanzaoren 186g, Sangjisheng 186g, Radix Paeoniae Rubra 89g, Ground Beetle 75g

[0035] Gansong 89g Coptidis 45g Southern Schisandra 67g Keel 149g

[0036] Preparation:

[0037] a) In the above prescription, ginseng was extracted three times with 70% ethanol under reflux, the first time was 3 hours, and each subsequent time was 2 hours, the extracts were combined, filtered, ethanol was recovered, concentrated, dried, crushed into fine powder, and set aside;

[0038] b) In the above prescription, Schisandra chinensis, Cornus officinalis, Salvia miltiorrhiza, Coptis chinensis, and Gansong are extracted three times with 70% ethanol under reflux, and the extracts a...

Embodiment 2

[0044]In order to facilitate the application of the Chinese medicine composition in the treatment of rheumatic heart disease, the Chinese medicine composition is prepared as a tablet

[0045] prescription:

[0046] Ginseng 45g Ophiopogon japonicus 112g Cornus officinalis 224g Salvia miltiorrhiza 225g Fried jujube seed 186g

[0047] Sangjisheng 186g Radix Paeoniae Rubra 89g Gansong 45g Wood Beetle 35g Coptidis 45g

[0048] Southern schisandra 67g, keel 149g.

[0049] Preparation:

[0050] a) In the above prescription, ginseng was extracted three times with 70% ethanol under reflux, the first time was 3 hours, and each subsequent time was 2 hours, the extracts were combined, filtered, ethanol was recovered, concentrated, dried, crushed into fine powder, and set aside;

[0051] b) In the above prescription, Schisandra chinensis, Cornus officinalis, Salvia miltiorrhiza, Coptis chinensis, and Gansong are extracted three times with 70% ethanol under reflux, and the extracts are c...

Embodiment 3

[0057] In order to facilitate the application of the Chinese medicine composition in the treatment of rheumatic heart disease, the Chinese medicine composition is prepared as granules

[0058] prescription:

[0059] Ginseng 175g Ophiopogon japonicus 192g Cornus officinalis 421g Salvia miltiorrhiza 440g Fried jujube seed 395g

[0060] Sangjisheng 396g Radix Paeoniae Rubra 188g Ground Beetle 98g Gansong 188g Coptidis 85g

[0061] Southern schisandra 147g, keel 278g.

[0062] Preparation:

[0063] a) In the above prescription, ginseng was extracted three times with 70% ethanol under reflux, the first time was 3 hours, and each subsequent time was 2 hours, the extracts were combined, filtered, ethanol was recovered, concentrated, dried, crushed into fine powder, and set aside;

[0064] b) In the above prescription, Schisandra chinensis, Cornus officinalis, Salvia miltiorrhiza, Coptis chinensis, and Gansong are extracted three times with 70% ethanol under reflux, and the extract...

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Abstract

The invention provides application of Chinese medicinal composition in preparation of medicament for treating rheumatic heart disease. The Chinese medicinal composition comprises the following Chinesemedicaments such as ginseng, dwarf lilyturf tuber, common macrocarpium fruit, danshen root, fried semen ziziphi spi, Chinese taxillus twig, red paeony root, ground beeltle, nardostachyos root and rhizome, and the like. The Chinese medicinal composition has the effects of tonifying qi and yin, invigorating the circulation of blood and removing obstruction, and clearing the heart fire and relievinguneasiness, and is proved to have remarkable effect of treating the rheumatic heart disease through clinical experiments.

Description

technical field [0001] The invention relates to the application of a traditional Chinese medicine composition in the preparation of medicines for treating rheumatic heart disease, belonging to the application field of Chinese herbal medicines. Background technique [0002] Rheumatic heart disease is a sequela of rheumatic fever, which is a heart disease left over and based on valvular disease after acute rheumatic fever causes carditis. The clinical manifestations are corresponding heart murmurs in the diseased valve area; enlarged ventricles and atria, and cardiac insufficiency in the later stage. Primary disease is the most common heart disease in my country. In adult cardiovascular diseases, primary disease accounts for about 40%. Most patients are young adults aged 20 to 40, and women are slightly more likely. Clinically, simple mitral valve disease is the most common, accounting for 70% to 80%, followed by mitral valve combined with aortic valve disease, accounting for...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8968A61K9/08A61K9/10A61K9/14A61K9/16A61K9/20A61K9/48A61P9/00A61P29/00A61K35/02A61K35/64
Inventor 郑立发李向军安军永王超李云鹏
Owner HEBEI YILING MEDICINE INST
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