Sitafloxacin hydrate injection and preparation method thereof
A technology for sitafloxacin and injection, applied in the field of medicine, can solve the problems of technical difficulties of injection, unstable aqueous solution, low solubility, etc., and achieve the effects of reducing impurities, increasing stability and improving curative effect
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example 1
[0028] prescription:
[0029] Sitafloxacin 50g
[0030] Sodium Benzoate 40g
[0032] Polyvinyl alcohol 0.4g
[0033] Sodium metabisulfite 10g
[0034] EDTA-2Na 0.75g
[0035] Phosphate buffer saline
[0036] Add water for injection to 1000ml
[0037]
[0038] Made into 500 pieces, 2ml / piece, 100mg / piece
example 2
[0040] prescription:
[0041] Sitasalate 50g
[0042] Sodium Salicylate 15g
[0043] Propylene glycol alginate 0.5g
[0044] Glucose 100g
[0045] EDTA-NaCa 0.75g
[0046] Vitamin C 1g
[0047] Add water for injection to 1000ml
[0048]
[0049] Made into 500 pieces, 2ml / piece, 100mg / piece
example 3
[0051] prescription:
[0052] Sitafloxacin 40g
[0053] Sodium Salicylate 12g
[0054] Sodium chloride 9g
[0055] Cremophor RH40 1.3g
[0056] Glutathione 3g
[0057] EDTA-2Na 0.68g
[0058] Phosphate buffer saline
[0059] Add water for injection to 1000ml
[0060]
[0061] Made into 200 pieces, 5ml / piece, 200mg / piece
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