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Artificial trachea cannula made of nano materials and preparation method thereof

A technology of artificial trachea and nanomaterials, applied in the direction of tracheal intubation, catheter, coating, etc., can solve the problems of poor lubricity and large irritation, achieve the effect of less drug dosage, high local concentration, and reduce damage

Inactive Publication Date: 2009-11-18
SHANGHAI NAT ENG RES CENT FORNANOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, when using this trachea, it is very irritating and has poor lubricity, and animal experiments show that its antibacterial properties also need to be further improved

Method used

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  • Artificial trachea cannula made of nano materials and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Such as figure 1 As shown, the present embodiment comprises: respirator connector 1, gas supply pipe 2, gas filling tube 3, inflatable air bag 4, liquid discharge tube 5 and lubricating coating 6, wherein: gas filling tube 3 is in the gas supply tube 2, and the gas supply tube 2 The output end is connected with the respirator connector 1, the insertion end of the trachea 2 is wedge-shaped, the outer wall of the trachea 2 is provided with an inflatable air bag 4, and the position of the inflatable air bag 4 is provided on the inflatable tube 3. 5 is inlaid on the outer wall of the air supply pipe 2 and is adjacent to the inflatable air bag 4, and the end of the liquid discharge pipe 5 close to the inflatable air bag 4 is provided with a liquid discharge port, and the other end of the liquid discharge pipe 5 is connected to the syringe. The outer wall of 2 is provided with lubricating coating 6.

[0035] This embodiment is prepared in the following ways:

[0036] The fi...

Embodiment 2

[0040] Embodiment 2: the present embodiment prepares and obtains such as by following way figure 1 Antimicrobial-lubricated artificial endotracheal tubes with composite nanomaterials shown:

[0041] The first step, with 3000g medical grade polyvinyl chloride (PVC), 15g nano-silver antibacterial material, 15g nano-zinc oxide, 60g piperacillin / tazobactam compound preparation, 1200g DINCH (BASF, HexamollDINCH), 30g stearic acid Calcium, 150g rare earth stabilizer, 450g polyvinyl acetate are fully and evenly mixed in a clean high-speed mixer;

[0042] The second step is to knead into flakes with a double-roll mill at a temperature of 160-180°C, and cut into pellets with a pelletizer to obtain medical antibacterial plastic masterbatches;

[0043] The third step is to use a twin-screw extruder to extrude the die head, plasticize and extrude the antibacterial plastic masterbatch, cool and shape it in a vacuum cooler, and then draw, cut and assemble the pipe to prepare Antibacterial...

Embodiment 3

[0045] Embodiment 3: the present embodiment prepares and obtains as follows figure 1 Antimicrobial-lubricated artificial endotracheal tubes with composite nanomaterials shown:

[0046] The first step, 3000g medical grade polyvinyl chloride (PVC), 120g nano-silver copper antibacterial material, 60g nano-titanium oxide, 300g moxifloxacin, 1200g DINCH (BASF, Hexamoll DINCH), 30g calcium stearate, 150g rare earth Stabilizer, 450g polyvinyl acetate is fully and evenly mixed in a clean high-speed mixer;

[0047] The second step is to fully and evenly mix in a clean high-speed mixer, knead into flakes with a double-roll mill at a temperature of 160-180°C, and cut into pellets with a pelletizer to obtain medical antibacterial plastic masterbatches;

[0048] The third step is to compound and mix the masterbatch with 25kg of medical grade polyvinyl chloride, use a twin-screw extruder, extrude the die head, plasticize and extrude the masterbatch, and then cool and shape the masterbatch ...

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Abstract

The invention relates to an artificial trachea cannula made of nano materials in the technical field of medical appliance and a preparation method thereof; the artificial trachea cannula comprises a respirator joint, an air supply tube, an inflation tube, an inflation gasbag, a drain pipe and a lubricant coating, wherein, the inflation tube is in the air supply tube, the output end of the air supply tube is connected with the respirator joint; an inserting section of the air supply tube is cuniform; the external wall of the air supply tube is provided with inflation gasbags; the position where the inflation tube is correspondingly arranged is provided with holes; the drain pipe is embedded on the external wall of the air supply tube and is adjacent to the inflation gasbag; the side of the drain pipe close to the inflation gasbag is provided with a liquid outlet, the other side thereof is connected with an injector; the lubricant coating is arranged on the external wall of the inflation gasbag and the air supply tube, the air supply tube and the inflation gasbag are made of modified plastics. With the method of the invention adopted, damage to lumen tissue when the tube is inserted is reduced, pain is reduced, complicating disease is prevented from occurring; in addition, the preparation process is easy and controllable, the cost is low, as a result, the method is applicable to batch production.

Description

technical field [0001] The invention relates to a device in the technical field of medical devices and a preparation method thereof, in particular to a nanomaterial artificial tracheal intubation tube with composite antibacterial and lubricating functions and a preparation method thereof. Background technique [0002] Biomedical polymer materials, such as artificial trachea, urinary catheter, suction tube, and tracheostomy catheter, are more and more widely used in clinical medicine. However, while these materials bring convenience to clinical treatment, there are still some problems. It has been found that biomaterials, whether long-term or short-term indwelling in the human body, often cause various bacterial infections. [0003] Existing artificial tracheal intubation tubes are generally made of polymer materials such as medical-grade polyvinyl chloride, medical-grade polyethylene, or medical-grade silicone rubber. However, during the use of artificial tracheal intubati...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M16/04A61L29/04A61L29/08A61L29/16A61L29/12A61L29/00
Inventor 盛小海洪月蓉刘洋陈玉云张冰陈超倪永何丹农
Owner SHANGHAI NAT ENG RES CENT FORNANOTECH
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