System for measuring distribution temperature in real time in laser-induced interstitial thermotherapy and data processing method

Abstract

The invention relates to a system for measuring distribution temperature in real time in laser-induced interstitial thermotherapy and a data processing method. The system comprises a laser light source, an energy-transfer multimode fiber and a sensing fiber grating, wherein the light emitted by the laser light source is introduced into neoplastic tissues through the energy-transfer multimode fiber, a grid region of the sensing fiber grating is arranged in the neoplastic tissues, the light emitted by a broadband light source is connected to the sensing fiber grating through a fiber coupler, a reflectance spectrum is connected to an optical spectrometer through the fiber, and the optical spectrometer is connected to a computer terminal. Reflectance spectrum data is input to the computer terminal, and the distribution temperature of the treated neoplastic part is obtained through a core inversion algorithm. The system has the advantages of simple structure, easy manufacture, low cost, high precision and strong practicability, and provides a reliable plan for the real-time measurement of the tissue temperature in the course of treatment.

Description

Technical field: [0001] The invention belongs to the intersecting field of optical fiber sensing and laser medicine, in particular to a real-time measurement system and data processing method of distributed temperature in laser-induced interstitial hyperthermia, which is used for real-time measurement of distributed temperature of tumor tissue area irradiated by laser during treatment . Background technique: [0002] Laser-induced interstitial thermotherapy (LITT, laser-induced interstitial thermotherapy) is a new tumor treatment technology that uses the thermal effect of laser to coagulate local tissues. It can achieve the purpose of tumor removal in situ through a small invasion. Compared with traditional surgery, it rarely causes massive bleeding. It has been used in the clinical treatment of tumors in brain, liver, breast, retina and other parts. Studies have shown that when the temperature of biological tissue reaches 60°C, it will cause the denaturation of protein and...

AI Technical Summary

Problems solved by technology

[0005] Aiming at solving the bottleneck of real-time temperature measurement in laser interstitial hyperthermia, the present invention provides a real-time measurement of distribution temperature in laser-induced interstitial hyperthermia with simple structure, easy manufacture, low cost, high precision and strong practicability System and data processing method, in the process of laser interstitial hyperthermia, the accurate temperature distribution of the treated part can be observed at any time, and then correct judgment can be made, which can ensure the safety of normal tissues or sensitive parts around the tumor

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