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Traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases

A technology of preparation and traditional Chinese medicine, which is applied in the field of Xinnao Litong preparations, can solve problems such as danger, and achieve the effects of low cost, high efficacy, and no side effects

Inactive Publication Date: 2009-09-09
JIANGXI HERBFINE HI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If transient ischemic attack is not treated in time, the 5-year mortality rate will reach more than 40%, which is very dangerous

Method used

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  • Traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases
  • Traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases
  • Traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0068] Experimental Example 1: Study on the protective effect of Xinnao Litong Formula on myocardial ischemia in rats caused by coronary artery ligation.

[0069] Process method:

[0070] The first process of formula 1, select salvia miltiorrhiza, ginkgo leaf, notoginseng, kudzu root, chuanxiong, hawthorn, lotus leaf respectively, add water and decoct twice, each time for 1-2 hours, combine the decoction, filter, and decompress the filtrate Concentrate into a thick paste, dry, crush into fine powder, add conventional auxiliary materials to make clinically acceptable dosage forms, such as tablets, capsules, granules and other dosage forms.

[0071] The second process of formula 1, select salvia miltiorrhiza, notoginseng, chuanxiong and lotus leaves respectively, add water to decoct twice, each time for 1-2 hours, combine the decoction, filter, and concentrate the filtrate under reduced pressure to form a thick paste, dry, Grind into fine powder and set aside; select Ginkgo bil...

experiment example 2

[0105] Experimental Example 2: Study on the protective effect of Xinnao Litong formula on acute cerebral ischemia.

[0106] Experimental grouping and dose design, experimental animals were randomly divided into 21 groups, 10 animals in each group: formula 1 process 1 all water extraction, process 2 partial water extraction + alcohol enhancement, medium and low dose three groups; formula 2 process 1 all water extraction , medium and low doses; formula 3 to formula 10, each group of medium doses, compared with Naoxuekang oral liquid group, Huayutong group, model control group, and normal control group.

[0107] ①Model animal group: 210 rats weighing 150-170 g were randomly divided into 21 groups, administered orally once a day from 8 days before the experiment to 1 hour before the operation, and both sides of the rats were ligated in each group except the normal control group. The common carotid artery caused acute experimental incomplete ischemia and was sacrificed 3 hours late...

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Abstract

The invention relates to a traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases, mainly containing one or more of Salvia miltiorrhiza, folium ginkgo, panax notoginseng, kudzuvine root Pueraria lobata, rhizoma ligustici wallichii, hawthorn and lotus leaf. The preparation method comprises the steps of selecting one or more of the Salvia miltiorrhiza, the folium ginkgo, the panax notoginseng, the kudzuvine root Pueraria lobata, the rhizoma ligustici wallichii and the hawthorn and lotus leaf, decocting, extracting active ingredients and concentrating the extracting solution to a certain concentration to obtain the Chinese traditional medicine preparation. In addition, the concentrated solution can be further made into capsules, tablets, granules, oral liquid, pills, pulvis, injection and sustained and controlled release preparations. Toxicologic and pharmacologic agent experiments show that the invention has no toxic side effect, is safe to use, has the functions of promoting blood circulation, remove blood stasis, reducing fat, freeing channels and eliminating phlegm and is suitable for phlegm stasis internal-block type cardiovascular and cerebrovascular diseases.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation and its preparation process, in particular to a kind of heart and brain which contains Danshen and one or more of Panax notoginseng, Ginkgo biloba, Pueraria lobata, Chuanxiong, hawthorn and lotus leaf, which are mixed or extracted separately. Litong preparation and its preparation process. Background technique [0002] Cardiovascular disease is a clinically important common frequently-occurring disease, characterized by acute onset, rapid change of condition, and high mortality. Coronary heart disease and high heart disease are common cardiovascular diseases in European and American countries. According to relevant statistics, in 1988, 6.08 million people in the United States suffered from coronary heart disease, and about 540,000 people died of it. Since the 1950s in our country, the morbidity and mortality of these two diseases have also been on the rise. Among them, the incidence o...

Claims

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Application Information

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IPC IPC(8): A61K36/734A61P9/10
Inventor 王跃生罗晓健饶毅范玫玫王金钱钱霞
Owner JIANGXI HERBFINE HI TECH
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