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Externally-applied plaster of bullatacin for resisting acquired immuno-deficiency syndrome virus

An anti-AIDS and virus technology, applied in the direction of antiviral agents, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problems of reducing economic costs, skin irritation, etc., to reduce toxic and side effects , strong drug loading capacity, and the effect of reducing toxic and side effects

Active Publication Date: 2008-09-10
贵州正鑫实业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The technical problem to be solved by the present invention is to provide a kind of external-use patch of bratasine anti-AIDS virus, which has not only solved the shortcomings of the previous oral or intravenous administration of anti-tumor drugs, but also overcomes the disadvantages of traditional external-use patches. It has the disadvantages of high skin irritation and certain toxicity, and reduces the economic cost

Method used

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  • Externally-applied plaster of bullatacin for resisting acquired immuno-deficiency syndrome virus
  • Externally-applied plaster of bullatacin for resisting acquired immuno-deficiency syndrome virus
  • Externally-applied plaster of bullatacin for resisting acquired immuno-deficiency syndrome virus

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1: Blatacine anti-AIDS external patch, which includes a backing layer, a drug reservoir and an anti-adhesive layer. A cotton medical non-woven fabric with good air permeability is used as the backing layer, and the drug reservoir is high Molecular gel acrylate pressure-sensitive adhesive is used as an adhesive, containing a prepared blattoxine liquid, and a polyester film treated with silicone oil as an anti-adhesive layer.

[0029] Blatacine medicinal solution is to dissolve 198 grams of blatacine parts in a 1100ml mixture of anhydrous ethanol and propylene glycol with a volume ratio of 1:1, stir well and mix well to make 20400 patches for external use. (Size: 7×10cm).

Embodiment 2

[0030] Example 2: The preparation method of blatacine anti-HIV topical patch, which includes the following steps: (1) Ingredients: dissolve 198 grams of blatacine part medicine in anhydrous volume ratio of 1:1 In the 1100ml mixture of ethanol and propylene glycol, fully stir to make it evenly mixed; (2) Adhesive preparation: pressure-sensitive adhesive is prepared by the production process of acrylate pressure-sensitive adhesive; (3) Coating: Blatacine is applied Mix the mixture of refined medicine, absolute ethanol and propylene glycol with the pressure-sensitive adhesive after heating and melting, and coat it on the anti-adhesive layer, and then cover the backing layer; (4) Slice: Cut into appropriate size (5× 7cm, 7×10cm, 9×12cm and other specifications); dry and cool, sealed and packaged with aluminum-plastic composite film.

Embodiment 3

[0031] Example 3: The following will further illustrate the beneficial effects of the drug of the present invention through drug clinical trials:

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Abstract

The invention discloses an anti-AIDS virus bullatacin patch for external use, which comprises a backing layer, a drug reservoir and an anti-sticking layer; a cotton medicinal non-woven fabrics with good permeability is used as the backing layer, a polymeric gel (an acrylate pressure-sensitive gel) as an adhesive; the patch comprises the prepared liquid of bullatacin, and a silicone-oil anti-sticking polyester film is functioned as an anti-sticking layer. The patch for external use has the advantages that not only the disadvantage of serious harmful and side effects of the existing oral or intravenous antitumor drug are solved, but also the disadvantage of heavy skin irritation and a certain extend of toxicity of traditional patches for external use are overcome, and the economic cost is reduced.

Description

Technical field [0001] The invention relates to an anti-AIDS virus external administration preparation, in particular to an anti-AIDS virus external application patch. Background technique [0002] AIDS, the full medical name of "Acquired Immune Deficiency Syndrome", is an infectious disease caused by human immunodeficiency virus, also known as HIV. HIV is abbreviated as HIV, which is a virus that can attack the human immune system. It takes the most important T4 lymphocytes in the human immune system as the target of attack, and swallows and destroys T4 lymphocytes in large quantities, thereby destroying the human immune system, and ultimately causing the immune system to collapse, causing the human body to lose its resistance to various diseases and develop disease. And die. In recent years, AIDS has spread more and more rapidly around the world, seriously threatening human health and social development, and has become the fourth killer threatening people’s health. It has attra...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K31/7048A61K47/32A61K47/34A61P31/18
Inventor 杨正强杨仁洲脱冰林周显勇张安袁胜伟
Owner 贵州正鑫实业有限公司
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