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Pharmaceutical combination for intestinal tract hemostasia and method of preparing the same

A composition and a technology for intestinal bleeding, which can be used in drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., and can solve problems such as unreported

Active Publication Date: 2008-08-27
深圳科康干细胞技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But so far, the clinical application of gastrointestinal (especially lower gastrointestinal) hemostasis with loess as the main prescription has not been reported.

Method used

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  • Pharmaceutical combination for intestinal tract hemostasia and method of preparing the same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Step 1: Take clay loess (collected in Heilongjiang Province or Hulunbeier City, Inner Mongolia, below one meter above the surface) and put it in a large bucket, add 20 times of clear water, and stir repeatedly to form a yellow mud soup. Filter twice with an 80-mesh sieve, discard the filter residue, leave the loess suspension, let stand to remove the supernatant (for example, it can stand for more than 24 hours), dry and pulverize the precipitated loess powder, and filter with a 120-mesh sieve After two times, sterilize it twice with ultraviolet radiation, one hour each time. The sterilized loess powder was sealed for future use.

[0034] Step 2. Take 1 equal part by weight of Bletilla striata, 1 equal part by weight of Panax notoginseng, and 1 equal part by weight of rhubarb. Rinse the above medicinal pieces with warm water for 2 times. Between ℃, dry for 24 hours, then mix together and pulverize, stir and then dry for 2 hours, pass through a 100-mesh sieve twice, and...

Embodiment 2

[0037] Step 1, with embodiment 1.

[0038] Step 2. Take 2 equal parts by weight of Bletilla striata, 2 equal parts by weight of Panax notoginseng, and 2 equal parts by weight of rhubarb. Rinse the above medicinal pieces with warm water for 2 times. Between ℃, dry for 24 hours, then mix together and pulverize, and then dry for 2 hours after stirring, pass through a 100-mesh sieve twice, and sterilize twice with ultraviolet radiation, each sterilization time is 30-40 minutes, The sterilized mixed medicine powder is sealed for future use.

[0039] Step 3: Take 8 equal parts by weight of the loess powder prepared by step 1, and put together 6 equal parts by weight of the mixed medicine powder prepared by step 2, stir evenly, and fill it into the international standard with a CGN-218 semi-automatic capsule filling machine. In the No. 0 capsule of the drug, it is checked regularly, and each batch of drugs is randomly checked before clinical application. Store in a cool and dry pla...

Embodiment 3

[0041] Step 1, with embodiment 1.

[0042] Step 2: Take 3 equal parts by weight of Bletilla striata, 3 equal parts by weight of Panax notoginseng, and 3 equal parts by weight of rhubarb. Rinse the above medicinal pieces with warm water for 2 times. Between ℃, dry for 24 hours, then mix together and pulverize, and then dry for 2 hours after stirring, pass through a 100-mesh sieve twice, and sterilize twice with ultraviolet radiation, each time for 30-40 minutes, The sterilized mixed medicine powder is sealed for future use.

[0043] Step 3: Take 48 equal parts by weight of the loess powder prepared in step 1, and put together 9 equal parts by weight of the mixed medicine powder prepared in step 2, stir evenly, and fill it with the CGN-218 semi-automatic capsule filling machine into the international standard In the No. 0 capsule of the drug, it is checked regularly, and each batch of drugs is randomly checked before clinical application. Store in a cool and dry place with a t...

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Abstract

The invention relates to a medicine combination used for intestinal hemostasis and a preparation method thereof. The medicine combination is mainly made from raw ingredients by weight parts as follows: loess powders are 4 to 16 parts, rhubarb is 1 to 2 parts, Bletilla striata is 1 to 2 parts, and panax notoginseng is 1 to 2 parts. The invention further relates to the application of the medicine combination for preparing the drugs which are used for treating intestinal bleeding and more particularly treating lower gastrointestinal bleeding.

Description

technical field [0001] The invention relates to a pharmaceutical composition for intestinal hemostasis and a preparation method thereof, in particular to a pharmaceutical composition for lower digestive tract hemostasis and a preparation method thereof. Background technique [0002] Gastrointestinal bleeding is a common clinical disease, which is divided into upper gastrointestinal bleeding and lower gastrointestinal bleeding. Lower gastrointestinal bleeding and upper gastrointestinal bleeding involve different parts, and lower gastrointestinal bleeding is mostly ileocecal bleeding (especially typhoid bleeding). It is customary to refer to bleeding in the esophagus, stomach, duodenum, pancreas, and biliary tract as upper gastrointestinal bleeding; bleeding in the jejunum, ileum, and large intestine is called lower gastrointestinal bleeding. Clinically, for the two kinds of gastrointestinal bleeding, the treatment methods are different, and the curative effects are also diff...

Claims

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Application Information

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IPC IPC(8): A61K36/708A61K36/898A61P7/04A61P1/00
Inventor 郭岩
Owner 深圳科康干细胞技术有限公司
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