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Pharmaceutical composition for treating pain and preparation thereof

A composition and drug technology, applied in the direction of drug combination, pharmaceutical formula, hydroxyl compound active ingredients, etc., can solve the problems of increased side effects, insignificant effect, and large side effects of morphine, and achieve elimination of inflammation, significant effect, and strong penetration force effect

Inactive Publication Date: 2008-08-06
黄孔新
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Pain can sometimes occur alone, but in cancer pain, these drugs are poorly compatible with morphine due to the administration of morphine in most cases, sometimes leading to increased side effects of morphine
Therefore, most of the current medicines for treating pain have insignificant effects and large side effects.

Method used

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  • Pharmaceutical composition for treating pain and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] A. Clematis 90g Notopterygium 50g Duhuo 50g Gentiana 50g Fangfeng 50g

[0091] Dilong 50g Drynaria 50g Dried Ginger 90g Triangular 50g Curcuma 50g

[0092] Qingfengteng 50g, Osteosa 60g, Guizhi 50g, Caulis Spatholobus 50g, Black Snake 50g

[0093] Haifengteng 50g Pepper 90g Yuanhu 50g Yangjinhua 50g Saponaria 50g

[0094] B. Nuxychia 60g, Raw Aconitum 60g, Lychee worm 50g, White mustard seed 30g, Piper 30g

[0095] Frankincense 30g Myrrh 30g Blood Dragon 30g Cinnamon 50g Asarum 30g

[0096] Whole insect 30g centipede 30g borneol 40g clove 30g camphor 20g

[0097] After soaking the above-mentioned class A raw materials in water for 1 hour, heat and decoct twice, and then decoct for 0.5 hours each time, filter the medicinal liquid, let the medicinal liquid stand for 24 hours, filter the supernatant and concentrate to a relative density of 1.1~ 1.20 (70-80°C) in the form of an extract for later use; separately pulverize the borneol and camphor of Class B...

Embodiment 2

[0099] A. Clematis 60kg, Notopterygium 65kg, Duhuo 35kg, Gentiana 65kg, Fangfeng 35kg

[0100] Dilong 65kg, drynaria 35kg, dried ginger 120kg, triangular 35kg, curcuma 65kg

[0101] Qingfengteng 35kg, Osteospermum 80kg, Guizhi 35kg, Millipeda 65kg, Black Snake 35kg

[0102] Sea Breeze Vine 65kg Pepper 60kg Yuanhu 65kg Yangjinhua 35kg Saponaria 65kg

[0103] B. Nuxychia 40kg, Aconitum 80kg, Lychee worm 35kg, White mustard seed 35kg, Piper 25kg

[0104] Frankincense 35kg Myrrh 25kg Blood Dragon 35kg Cinnamon 35kg Asarum 35kg

[0105] Whole insect 25kg centipede 35kg borneol 30kg clove 35kg camphor 25kg

[0106] The above-mentioned medicine is prepared into a spray by adding conventional adjuvants according to a conventional process.

Embodiment 3

[0108] A. Clematis 120kg, Notopterygium 35kg, Duhuo 65kg, Gentiana 35kg, Fangfeng 65kg

[0109] Dilong 35kg, drynaria 65kg, dried ginger 60kg, triangular 65kg, curcuma 35kg

[0110] Qingfengteng 65kg, Osteosa 40kg, Guizhi 65kg, Millipeda 35kg, Black Snake 65kg

[0111] Sea Breeze Vine 35kg Pepper 120kg Yuanhu 35kg Yangjinhua 65kg Saponaria 35kg

[0112] B. Nuxychia 80kg, Aconitum 40kg, Cuttlefish 65kg, White Mustard Seed 25kg, Piperia 35kg

[0113] Frankincense 25kg Myrrh 35kg Blood Dragon 25kg Cinnamon 65kg Asarum 25kg

[0114] Whole insect 35kg centipede 25kg borneol 50kg clove 25kg camphor 25kg

[0115] The above-mentioned medicine is made into a liniment by adding conventional auxiliary materials according to a conventional process.

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PUM

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Abstract

The invention discloses a medicine composition for treating pains, which substantially comprises clematis root, Notopterygium root, pubescent angelica, root of gentian, radix saposhnikoviae, lumbricus, Drynaria fortunei, dried ginger, etc., 35 raw medicinal medicines. The medicine composition of the invention has stronger penetrating power, good transdermal adsorption, which can increase the temperature of a lesion location, improve the blood circulation, eliminate an inflammation, unblocking a dampness blocking channel and clearing off the congestion, has remarkable effects on rheumatism pains, cancer pains, stomach cold ache and all pains resulted from cervical and lumbar hyperosteogeny, traumatic injury, fascial strain, sciatica, scapulohumeral periarthritis, etc.

Description

technical field [0001] The invention relates to a pharmaceutical composition, in particular to a pharmaceutical composition for treating pain and a preparation method thereof. Background technique [0002] Usually, pain is generated at the tissue part due to tissue disturbance, and when the tissue disturbance at the painful part disappears, the pain also disappears. Pain sometimes occurs alone, but in cancer pain, in most cases, due to the administration of morphine, these drugs are poorly compatible with morphine, sometimes leading to increased side effects of morphine. Therefore most of the medicines for the treatment of pain currently have insignificant effects and large side effects. Contents of the invention [0003] The object of the present invention is to provide a pharmaceutical composition for treating pain. [0004] Another object of the present invention is to provide a preparation method of the pharmaceutical composition. [0005] Another object of the pres...

Claims

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Application Information

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IPC IPC(8): A61K36/9068A61K9/06A61K9/12A61K9/14A61P25/04A61P29/00A61K31/045A61K31/125A61K35/58A61K35/64A61K35/583
Inventor 黄孔新
Owner 黄孔新
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