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Broccoli seed extractive and preparing method thereof

A technology for broccoli seeds and extracts, which is applied in the directions of drug combinations, pharmaceutical formulations, plant raw materials, etc., can solve the problems that the active ingredients cannot be released well, destroy enzyme activity, etc., and achieves convenient portability, cancer prevention, and easy storage. Effect

Inactive Publication Date: 2008-07-30
GUANGDONG PHARMA UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, the processing method of broccoli for family diet often destroys the activity of enzymes in the plant, so that the active ingredients in the vegetable cannot be released well and absorbed by the human body

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] After the broccoli seeds are fully crushed, pass through a 20-mesh sieve, add 30 times the weight of distilled water for hydrolysis; after filtration, the slag is fully washed with water and centrifuged; the hydrolyzate is degreased with excess n-hexane; the degreased hydrolyzate is added with ethanol (0.2ml ethanol / 1ml hydrolyzate) to inactivate myrosinase, and the hydrolyzate was concentrated in a water bath (70° C.) to obtain broccoli seed extract.

[0022] Adding auxiliary materials such as starch, sucrose, dextrin, glucose, calcium sulfate and microcrystalline cellulose to the obtained broccoli seed extract, adjusting the pH to 3.5, drying into powder, and pressing into tablets.

Embodiment 2

[0024] After the broccoli seeds are fully crushed, pass through a 20-mesh sieve, add 10 times the weight of deionized water for hydrolysis; after centrifugation, the slag is fully washed with water and filtered; the hydrolyzate is degreased with excess petroleum ether; the degreased hydrolyzate is added with ethanol (0.04ml ethanol / 1ml hydrolyzate) inactivated myrosinase, and the hydrolyzate was concentrated in a water bath (60° C.) to obtain broccoli seed extract.

[0025] Adding auxiliary materials such as starch, sucrose, dextrin, glucose, calcium sulfate and microcrystalline cellulose to the obtained broccoli seed extract, adjusting the pH to 3.5, drying into powder, and pressing into tablets.

Embodiment 3

[0027] After the broccoli seeds are fully crushed, pass through a 20-mesh sieve, add 60 times the weight of distilled water for hydrolysis; after centrifugation, the slag is fully washed with water and centrifuged; the hydrolyzate is degreased with excess n-hexane; the hydrolyzate after degreasing is added with ethanol (1ml ethanol / 1ml hydrolyzate) to inactivate myrosinase, and the hydrolyzate was concentrated in a water bath (100° C.) to obtain broccoli seed extract.

[0028] Adding auxiliary materials such as starch, sucrose, dextrin, glucose, calcium sulfate and microcrystalline cellulose to the obtained broccoli seed extract, adjusting the pH to 3.5, drying into powder, and pressing into tablets.

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PUM

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Abstract

The invention discloses a seed extract of Broccoli and relevant preparation method. The preparation method is to receive the extract of the Broccoli seed hydrolyzing, degreasing, inactivating, and condensing the seed of the Broccoli and to receive a health product by adding auxiliary materials. The main components of the Broccoli extract of the invention is compounds of isothiocyanate; wherein, sulforaphane is the most activated compound with maximal content, and sulforaphane is also the isothiocyanate compound with maximal cancer-prevention activity. The health product containing the Broccoli extracts can effectively help human body improve the resistance to toxicants after the proof of animal experiment, thereby effectively reducing the formation of tumor induced by chemical matters.

Description

technical field [0001] The invention relates to broccoli seeds, in particular to a broccoli seed extract and its preparation technology. Background technique [0002] Broccoli, also known as green cauliflower, broccoli, etc., is a variety of Brassica cabbage species that uses green curds as products. Studies have shown that broccoli is effective in fighting breast and colorectal cancer. Regular consumption of broccoli by healthy people can also prevent cancer. Therefore, broccoli is known as the "new star in cancer prevention". [0003] my country is a country with a large population. At present, the average annual number of cancer patients in my country is about 1.8 million to 2 million, and the number of deaths is about 1.4 million to 1.5 million. If no prevention and control is carried out, the number of cancer deaths in my country will double in the next 20 years. [0004] The amount of sulforaphane obtained by simply eating broccoli vegetables cannot effectively prev...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/31A61K9/20A61P35/00A61K131/00
Inventor 冯毅凡郭晓玲孟青张婵娟梁汉明
Owner GUANGDONG PHARMA UNIV
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