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Method for treating lincomycin fungi residues

A lincomycin and treatment method technology, applied in the field of lincomycin residue treatment, can solve the problems of difficult treatment, environmental pollution, lincomycin is not easy to degrade and remove, and achieve huge economic and social benefits Effect

Inactive Publication Date: 2008-07-23
南阳普康药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Though there is a kind of method that EM bacterium is used for processing antibiotic dregs, as the application number is 200510012998.8 utilizes biotechnology to carry out the method for harmless treatment of antibiotic dregs, but this method is used for the processing of lincomycin dregs, After drying, the crude protein of nutrients increased from 36.545% to 41.36%, and the total amino acid increased from 0.169% to 0.406%, but the residual amount of lincomycin was only reduced from 235.468mg / g to 129.763mg / g, which still could not be degraded and cleared The purpose of lincomycin residue
Due to the stable chemical properties of lincomycin, the residual lincomycin in the fungus residue is not easy to be degraded and removed. Turning waste into treasure and comprehensive utilization of bacterial residues has become a top priority

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Main ingredients: fresh lincomycin residue 2kg;

[0013] Accessories: bran 0.5kg, brown sugar 0.06kg, sodium bicarbonate 0.03kg, salt 0.16kg, peanut shell 1.25kg;

[0014] Bacteria: EM bacteria stock solution 80ml.

[0015] Approach:

[0016] (1). 0.5kg of bran will be mixed with 1.25kg of peanut shells and crushed;

[0017] (2). Add 0.03 kg of sodium bicarbonate to 2 kg of fresh lincomycin residue, then add 0.16 kg of salt, adjust the pH value to 5.5 with quicklime water, and then mix it with bran and peanut shells;

[0018] (3). Add 80ml of EM bacteria stock solution, add 0.06kg of brown sugar, and add water to 500ml;

[0019] (4). Add the EM bacteria stock solution prepared in step 3 to the mixture prepared in step 2, mix evenly, add water and humidity, and knead into a ball by hand. It is easy to disperse when touched, and then put it into a container for compaction and airtight ;

[0020] (5). The temperature of the fermented product is kept at 30°C, and the f...

Embodiment 2

[0022] Main ingredients: fresh lincomycin residue 3kg;

[0023] Accessories: bran 0.5kg, brown sugar 0.06kg, sodium bicarbonate 0.03kg, salt 0.16kg, peanut shell 1.25kg;

[0024] Bacteria: EM bacteria stock solution 135ml.

[0025] Approach:

[0026] (1). 0.5kg of bran will be mixed with 1.25kg of peanut shells and crushed;

[0027] (2). Add 0.03 kg of sodium bicarbonate to 3 kg of fresh lincomycin residue, then add 0.16 kg of salt, adjust the pH value to 5.8 with quicklime water, and then mix it with bran and peanut shells;

[0028] (3). Add 135ml of EM bacteria stock solution, add 0.06kg of brown sugar and add water to 500ml;

[0029] (4). Add the EM bacteria stock solution prepared in step 3 to the mixture made in step 2, mix evenly, add water and humidity, and knead into a ball by hand. It is easy to disperse when touched, and then put it into a container for compaction and airtight ;

[0030] (5). The temperature of the fermented product is kept at 35°C, and the ferm...

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PUM

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Abstract

The invention discloses a processing method of lincomycin fungus dregs, effectively settling the problem of degradation and clearance of residual lincomycin inside the fungus dregs and enabling the regeneration and reuse of wastes. The processing method of lincomycin fungus dregs can be realized through the following steps: the lincomycin fungus dregs, EM bacteria stock solution, accessories and water are used as materials; wherein, the total weight ratio of the lincomycin and the accessories is 1 to 3:1; the accessories comprise bran, brown sugar, sodium bicarbonate, table salt and peanut shell with the weight ratio of 50:6:3:16:125; wherein, the bran and the peanut shell are pulverized, then the sodium bicarbonate and table salt are added to the lincomycin fungus dregs in series, 40 to 50ml EM bacteria stock solution is measured for 1kg lincomycin fungus dregs added with brown sugar and diluted by water to 250ml, forming EM bacteria stock diffusion solution; then the EM bacteria stock diffusion solution is added to the mixture and mixed uniformly, added with water, and stored in a vessel for fermentation. The processing method of lincomycin fungus dregs has the advantages of simple method, waste reuse, and great economic and social benefits.

Description

1. Technical field [0001] The invention relates to the field of biopharmaceuticals, in particular to a treatment method for lincomycin residue. 2. Background technology [0002] Antibiotic mycelium waste is referred to as antibiotic slag, which is the waste of antibiotic production enterprises in the process of producing antibiotics. Various antibiotic fermentation media and fermentation processes are different as well as different cultured fungi. Residues also vary or even vary greatly. For many years, antibiotic residues have been regarded as solid waste generated during industrial production and discarded, resulting in waste of resources and environmental pollution. In recent years, domestic anaerobic fermentation of EM bacteria to treat penicillins, cephalosporins, erythromycin, tetracyclines, aminoglycosides, macrolides, polypeptides, and chloromycins has been reported in the literature. There are no literature and reports on the treatment of lincomycin residue. [0...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C05F5/00C05F17/00A23K20/195
CPCY02A40/20Y02W30/40
Inventor 李静仁马玉红李喆张永杰张文峰夏红伟赵晴曹中祥张小贝路建同王冰李红德段永平李谧张小兵尹正彦
Owner 南阳普康药业有限公司
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