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Novel uses of compound seabuckthorn seed oil in preparing medicine

A technology of sea buckthorn seed oil and compound recipe, which is applied in the pharmaceutical field of compound sea buckthorn seed oil

Active Publication Date: 2008-07-23
陕西海天制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After further experimental research and exploration, the applicant found that the compound seabuckthorn seed oil preparation can not only be used to treat cervical erosion and vaginitis caused by women's hot and humid betting, but also has a new drug use, that is, it can be used for cervical erosion after physical therapy. surface repair and the treatment of mild and moderate dysplasia of cervical intraepithelial neoplasia, but so far there is no related report

Method used

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  • Novel uses of compound seabuckthorn seed oil in preparing medicine
  • Novel uses of compound seabuckthorn seed oil in preparing medicine
  • Novel uses of compound seabuckthorn seed oil in preparing medicine

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Embodiment Construction

[0011] The present invention will be further elaborated below through the preparation of the compound seabuckthorn seed oil suppository and the preclinical pharmacodynamic test carried out on it.

[0012] 1. Preparation of compound seabuckthorn seed oil suppository

[0013] Take 150g of cnidium, 80g of flavescens, 150g of calamine, 50g of frankincense and 50g of myrrh and grind them into fine powder; take another 20g of borneol, grind them into fine powder, mix them with the above powder, and mix them well; Heat and melt in a water bath at ℃, add 500g of seabuckthorn seed oil and 150ml of water at the same temperature, emulsify quickly until it becomes a viscous gel, add the above powder, mix well, pour into the plug mold after the bubbles disappear, cool, and granulate to obtain Compound seabuckthorn seed oil suppository.

[0014] Usage and dosage: vaginal administration. Cervical erosion and cervical intraepithelial neoplasia start medication after menstruation is clean; c...

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Abstract

The invention discloses a novel application of compound seabuckthorn oil in pharmacy, that is, the compound seabuckthorn oil in preparing drugs for repairing trauma surface after physical therapy of cervical erosion and light to medium degree atypical hyperplasia of cervical intraepithelial neoplasia. Proved by pharmacodynamics test and study, the compound seabuckthorn oil suppository has a certain treatment effect on animal vagina and cervicitis model caused by chemical burn and biological factors infection and on light to medium degree atypical hyperplasia of cervical intraepithelial neoplasia and can present preclinical effectiveness on the therapy of cervical erosion and on light to medium degree atypical hyperplasia of cervical intraepithelial neoplasia.

Description

Technical field: [0001] The present invention relates to the new application of compound seabuckthorn seed oil in pharmaceuticals, especially in the preparation of compound seabuckthorn seed oil for the repair of wound surface after physical therapy of cervical erosion and mild and moderate dysplasia of cervical intraepithelial neoplasia The purposes of the invention belong to the technical field of traditional Chinese medicine. Background technique: [0002] Cervical erosion is the most common pathological change of chronic cervicitis. Due to inflammatory stimulation, the covering epithelial cells on the surface of the cervix fall off, while the lower columnar epithelial cells protrude outward to replace the peeling covering epithelium; the capillaries of the columnar epithelium Revealed, so that the inflammatory area was bright red, so it is called cervical erosion. The erosion surface is covered by a complete single-layer columnar epithelium of the cervical canal. Becaus...

Claims

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Application Information

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IPC IPC(8): A61K36/489A61K9/02A61P15/00A61P35/00A61K33/30A61K31/045
Inventor 王春王宇张国莹王辉
Owner 陕西海天制药有限公司
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