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Compound eugenol nano emulsion composition and preparation thereof

A nanoemulsion and composition technology, applied in the field of daily chemical industry, can solve the problems of ineffective treatment of skin itching, swelling and pain, inability to quickly relieve patients' pain, and short time limit for repelling mosquitoes, so as to achieve easy popularization and application and good penetration ability , Good wetting effect

Inactive Publication Date: 2008-07-09
NORTHWEST A & F UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Products currently on the market for preventing mosquito bites include mosquito repellent coils, electric heating mosquito coils, liquid mosquito coils, and mosquito repellent water, anti-mosquito water, toilet water, cooling oil, etc., but the functions of the above products are single, and toilet water and other products are volatile. Mosquito repellent time is short, cooling oil and other products have no obvious effect on skin itching, swelling and pain caused by mosquito bites, and cannot quickly relieve patients’ pain. Moreover, most of these products are oily, and they are easy to contaminate clothes when applied, causing harm to patients. unnecessary trouble

Method used

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  • Compound eugenol nano emulsion composition and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] 1) Weigh polyoxyethylene ether 40 hydrogenated castor oil 30.5g, eugenol, 10.0g, eucalyptus oil 0.5g, peppermint oil 0.1g, paeonol 0.1g, citronella oil 0.05g, camphor 0.05g, anhydrous Ethanol 0.2g, distilled water 75.1g, spare;

[0029] 2) adding the amount of camphor and paeonol into absolute ethanol and stirring until fully dissolved as co-emulsifier;

[0030] 3) Stir and mix the eucalyptus oil, eugenol, paeonol, peppermint oil and citronella oil as the oil phase;

[0031] 4) Add the amount of polyoxyethylene ether 40 hydrogenated castor oil and absolute ethanol in 2 to the oil phase in 3 and mix;

[0032] 5) Use distilled water as the water phase, stir the oil phase rapidly at room temperature, slowly add the water phase dropwise while stirring, and keep stirring until the system becomes a transparent liquid, which is the compound eugenol nanoemulsion composition of the present invention.

Embodiment 2

[0034] Polyoxyethylene ether 40 hydrogenated castor oil 25.0g Eugenol 7.0g

[0035] Eucalyptus oil 1.0g Peppermint oil 0.5g

[0036] Paeonol 0.6g Citronella Oil 0.2g

[0037] Camphor 0.3g Absolute ethanol 0.5g

[0038] Distilled water 62.1g

Embodiment 3

[0040] Polyoxyethylene ether 40 hydrogenated castor oil 20.5g Eugenol 4.0g

[0041] Eucalyptus Oil 1.0g Peppermint Oil 1.0g

[0042] Paeonol 1.6g Citronella Oil 0.6g

[0043] Camphor 1.6g Absolute ethanol 1.5g

[0044] Distilled water 41.3g

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Abstract

The present invention discloses an eugenol nano emulsion compound, characterized in that the granule diameter of the nano emulsion compound is within 1 to 100nm; the raw materials with weight percentage includes 1.0 to 10.0 percent of eugenol, 0.5 to 8.0 percent of eucalyptus oil, 0.1 to 6.0 percent of pennyroyal, 0.1 to 3.0 percent of paeonol, 0.05 to 5.0 percent of citionella oil, 0.05 to 3.0 percent of camphor, 7.5 to 35.3 percent of emulsifying agent, 0.2 to 3.8 percent of co-emulsifier and the rest of water; the total weight percentage of the raw materials is 100 percent. The eugenol nano emulsion compound has the functions of dispelling mosquitoes, relieving itching, killing pain, reducing inflammation and resisting bacteria. The present invention is used to dispel mosquitoes and rapidly relieve itching and red swelling on the skin after bitten by mosquitoes. The present invention has the advantages of strong permeability, good stability, good invasive, long acting time, significant effect, simple preparation method and easy promotion and application.

Description

technical field [0001] The invention belongs to the field of daily chemical industry, and relates to a compound eugenol nanoemulsion composition with high-efficiency mosquito repelling, antipruritic, analgesic, anti-inflammatory and antibacterial properties and a preparation method thereof. Background technique [0002] During the hot season, bare skin is most likely to be bitten by mosquitoes. After the skin at the bite site is affected by the toxin, in addition to the needle-like injury, the surrounding areas often show allergic reactions, local congestion and edema, causing local pain and itching. Infants and young children often scratch with their hands, which can cause local infection. After local infection in some children, it can expand upward along the lymphatic vessels, causing red lines on the skin and enlarged lymph nodes in the corresponding parts, and even suppuration. In addition to causing pruritus in humans or animals, mosquito bites can also transmit pathog...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61K47/34A61K8/06A61Q17/00A61K31/125A61K31/122A61K31/05A61K47/44
Inventor 欧阳五庆杨卫超
Owner NORTHWEST A & F UNIV
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