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Three-dimensional conformal Irradiation unit of heavy ion beam on tumour target area

A heavy ion beam and three-dimensional conformal technology, which is applied in the field of heavy ion beam irradiation devices in the biomedical field, can solve the problems of low conformal degree, scatterers reduce beam quality, and the proportion of healthy tissues is reduced. , to achieve a high degree of conformity, reduce the probability of normal tissue complications, and reduce the effect of normal tissue complications

Active Publication Date: 2008-06-18
国科离子医疗科技有限公司
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  • Summary
  • Abstract
  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to give full play to the advantages of heavy ion beams in radiotherapy, the purpose of the present invention is to overcome the shortcomings of the current two-dimensional conformal irradiation therapy, such as the low degree of conformation and the reduction of beam quality by scatterers. We based on passive beam distribution The system provides a device for performing three-dimensional conformal irradiation therapy on the tumor target area with heavy ion beams, so that the high-dose Bragg peak area of ​​the heavy ion beam falls completely on the tumor target area, and the proportion of healthy tissues irradiated by the high-dose area greatly reduced

Method used

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  • Three-dimensional conformal Irradiation unit of heavy ion beam on tumour target area
  • Three-dimensional conformal Irradiation unit of heavy ion beam on tumour target area
  • Three-dimensional conformal Irradiation unit of heavy ion beam on tumour target area

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Embodiment 1

[0026] The present invention takes the chemically etched solid nuclear track detector CR39 sheet as an example to illustrate the three-dimensional conformal irradiation of the heavy ion beam on the target area composed of the CR39 sheet.

[0027] Utilize the 80.55MeV / u carbon ion beam provided by Lanzhou Heavy Ion Research Facility (HIRFL) of Institute of Modern Physics, Chinese Academy of Sciences, we scan the magnet in the present invention at the HIRFL shallow layer tumor heavy ion therapy terminal equipped with passive beam distribution system The uniform irradiation field formed by the system and the mini ridge filter were used to test the broadening of the beam Bragg.

[0028] Such as figure 1 As shown, the device for performing three-dimensional conformal irradiation therapy on tumor target area with heavy ion beam, including scanning magnet system 1, beam current monitoring system 2, mini ridge filter 3, range shifter 4, multi-leaf collimator 5 and the patient's body ...

Embodiment 2

[0033] Using the device described in Example 1 to implement three-dimensional conformal radiation therapy on the tumor target area, the present invention is a phantom stacked with tissue-equivalent material CR39 thin slices (thickness 0.66mm, water equivalent length coefficient 1.061) As an example, to illustrate the three-dimensional conformal irradiation of a carbon ion beam to a target area composed of CR39 flakes.

[0034] Integrating all the devices in the present invention has carried out three-dimensional conformal irradiation on the phantom stacked by tissue equivalent material CR39 thin slices, and the tumor slice is seven slices thereof, such as Figure 7 As shown in the middle left figure, along the beam penetration direction, the tumor slices are circles with diameters of 10mm, 20mm, 30mm, 40mm, 30mm, 20mm and 10mm. In the irradiation, the scanning frequency of the scanning magnet system in 1x direction is 75Hz, the scanning frequency in the y direction is 45Hz, th...

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Abstract

The invention relates to a device used in 3-D conformal radiotherapy to gross tumor volume with heavy ion beams, comprising a magnet scanning system, a beam monitor system, a mini-ridge filter, a range shifter, a multi-leaf collimator and a patient body surface compensator, which are sequentially arranged on the body surface of the patient. The centers of the components and the center of the gross tumor volume are located at the beam axis. The invention overcomes the defects that the conformality is low and the scatterer impairs beam quality in current 2-D conformal radiotherapy by heavy ion beams based on a passive beam flow distribution system, and adopts 3-D conformal irradiation without the scatterer needed in current 2-D conformal radiotherapy, thus improving conformality in the therapy to the gross tumor volume with heavy ion beams. The invention can protect the health organs around the gross tumor volume to the largest extent and reduce incidence of disease at the normal organs without reducing the rate of using large quantity of Bragg peak to efficiently kill the cells in the gross tumor volume, thus improving curative effect of the heavy ion beams.

Description

technical field [0001] The invention relates to a device for irradiating heavy ion beams in the field of biomedicine, in particular to a device for performing three-dimensional conformal radiation therapy on tumor target areas by heavy ion beams. Background technique [0002] Heavy ion beams are known as the most ideal rays for radiotherapy in the 21st century. The device can realize the three-dimensional conformal irradiation of the heavy ion beam on the tumor target area. The three-dimensional conformal irradiation technology can give full play to the advantages of heavy ion beams in cancer treatment, kill tumor cells in the target area to the greatest extent, and at the same time protect the healthy tissues around the tumor target area from damage to the greatest extent, and reduce the complications of normal tissues. It can improve the conformity degree of heavy ion beam therapy, thereby improving the curative effect of heavy ion beam radiation therapy. [0003] Heavy ...

Claims

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Application Information

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IPC IPC(8): A61B6/00
Inventor 李强肖国青戴中颖
Owner 国科离子医疗科技有限公司
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