Anti-tumor medicine extracted from Juglans regia and preparation method thereof

Abstract

The invention discloses an antitumor drug extracted from walnut bark, which relates to a medical preparation, at the same time, which relates to the extracted isolate of walnut bark. The drug is a medicine taking 8-hydroxy-2-methoxy-1 and 4-naphthoquinone as active components; the preparation method includes two stages of extracting active materials and preparing antitumor drugs, wherein the stage of extracting isolate has five steps: (1) the walnut bark is made into the shape of mungbean noodle and extracted by alcohol; (2) an extractum is obtained by concentrating the extracting solution; (3) an extract is obtained by extracting the extractum with an extracting agent;(4) the extractum of the extract is dissolved by a soda solution and extracted by chloroform, thus obtaining the extractum; (5) part of the extractum is dissolved by chloroform and separated by column chromatography, thus obtaining 8-hydroxy-2-methoxy-1 and 4-naphthoquinone. In the preparing stage, with starch and soybean protein, an extracted HT-12 is made into oral reagent by a routine method, or made into an oral reagent directly with the extractum, or prepared into an injection solution with distilled water. The invention has the advantages that the supplied drug is an antitumor drug which can be used for treating and preventing cancer and serving for human health.

Description

technical field [0001] The present invention relates to medical preparations, and simultaneously relates to the extraction and separation of walnut bark, in particular, relates to the antitumor drug extracted from the walnut bark. Background technique [0002] Plants of the genus Juglans belong to the family Juglandaceae of the angiosperm dicotyledonous class Juglandaceae. Branches, leaves, exocarp, root bark, nuts and kernels of walnut (Juglans regia) can be used as medicine. Walnuts have a high curative effect on diseases such as urinary system stones, chronic bronchitis, dermatitis, eczema and dysentery. The extract of walnut bark is useful among the people to treat cancer. [0003] Literature research shows that the research on Juglans plants is mainly concentrated on planting, food processing, etc., and the research on its chemical composition and activity is also mainly concentrated on the root bark of black walnut (J. , bark and green fruit. There are relatively f...

AI Technical Summary

Problems solved by technology

But there is no report of extracting antineoplastic drugs from walnut bark