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New use of wrinkled glanthyssop vital energy preparation

A Huoxiangzhengqi preparation technology, applied in the Huoxiangzhengqi preparation in the field of pharmacy

Inactive Publication Date: 2008-02-20
CHONGQING DAYI TECHONLOGY INVESTMENT
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is no literature report on the effect of Huoxiangzhengqi preparation on VIP

Method used

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Examples

Experimental program
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Effect test

experiment example

[0015] Get 80 healthy adult Wistar rats, divide the rats into Huoxiangzhengqi oral liquid group (administer Huoxiangzhengqi oral liquid 10ml / kg) and control group (administer the same volume of normal saline) according to random number table method, each group The animals were further divided into two groups (each group was a time point, and two time points were set at 1 and 6 hours). Finally, there were 20 animals in each group. Each group was injected with medicine or normal saline, 2% DB-2000 0.4ml was injected 20min before laparotomy to collect specimens, intraperitoneal injection of 1% pentobarbital sodium 30mg / kg was anesthetized, laparotomy was used to collect inferior vena cava blood , and use the literature method to determine (Journal of Tianjin Medical University 1996.2: 12-13 Xi Shuqing, Zhang Moling, Ma Liyun, etc. "Immunohistochemical Observation of Motilin in Rat Brain") the relative residual rate of DB-2000 in the stomach and the propulsion ratio of the small in...

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Abstract

The present invention discloses a new usage of a preparation of agastachis for restoring health, in particular to the usage of the preparation of agastachis for restoring health in the preparation of the drugs for lowering the vasoactive intestinal peptide. More particularly, the present invention is the application of the preparation of agastachis for restoring health in the preparation of the drugs for lowering the vasoactive intestinal peptide in the plasma; the application in the preparation of the drugs for lowering the vasoactive intestinal peptide in the gastric antrum tissue homogenate; the application in the preparation of the drugs for lowering the vasoactive intestinal peptide in the jejunum tissue homogenate; the application in the preparation of the drugs for lowing the vasoactive intestinal peptide positive products in the gastric antrum, jejunum mucosa and myenteric plexus; and the application in the preparation of the drugs for lowering vasoactive intestinal peptide and promoting gastric motility. The pharmacological studies show that the preparation of agastachis for restoring health can reduce the release of vasoactive intestinal peptide and promote the gastric motility.

Description

technical field [0001] The invention relates to the application of Huoxiangzhengqi preparation, in particular to the application of Huoxiangzhengqi preparation in the field of pharmacy. Background technique [0002] Huoxiangzhengqi San was recorded in "Taiping Huimin Heji Jufang" in the Song Dynasty. In the early years, it was mostly used for abdominal distension, anorexia, nausea, and vomiting caused by exogenous wind and cold and internal injury and stagnation of dampness. The 2005 edition of the Pharmacopoeia records that Huoxiangzhengqi preparations have the functions and indications of "relieving the exterior and removing dampness, regulating qi and harmonizing the middle. It is used for colds caused by exogenous wind-cold, internal injury damp stagnation, or summer injury and summer dampness. Abdominal distension and pain, vomiting and diarrhea; stomach-intestinal cold with the above symptoms." [0003] Vasoactive intestinal peptide (VIP) is a representative and well-...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61P1/14A61P43/00
Inventor 杨国汉胡德耀戴裕光卿玉玲秦少容
Owner CHONGQING DAYI TECHONLOGY INVESTMENT
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