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Curcuma extract and its prepn process, medicine composition and use

A kind of turmeric extract and extract technology, applied in the field of turmeric extract and its preparation, can solve the problem that the pharmacological research of turmeric extract has not yet been reported and the like

Inactive Publication Date: 2010-03-24
GUIZHOU NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the extraction of turmeric generally adopts the conventional water extraction and alcohol precipitation method or alcohol extraction method, but there is no report on the pharmacology of turmeric extract.

Method used

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  • Curcuma extract and its prepn process, medicine composition and use
  • Curcuma extract and its prepn process, medicine composition and use
  • Curcuma extract and its prepn process, medicine composition and use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0087] Embodiment 1 of the present invention: the preparation of turmeric water extract:

[0088] Take 10 kg of dried turmeric rhizome, crush it into a coarse powder, add 10 times the amount of water to decoct twice, for 2 hours for the first time, and 1.5 hours for the second time, filter, combine the filtrates, concentrate to 60 ° C and measure the relative density to 1.30, Let it cool, add ethanol to make the alcohol content 70%, let it stand overnight, take the supernatant and concentrate it under reduced pressure to a thick paste with a relative density of 1.25, dry it under reduced pressure at 75°C to obtain 290g of turmeric water extract.

Embodiment 2

[0089] Embodiment 2 of the present invention: the preparation of turmeric ethanol extract:

[0090] Get 10 kg of curcuma rhizome dry product, grind it into coarse powder, add 8 times the amount of 75% ethanol to reflux and extract twice, each time for 2 hours, filter, combine the filtrate, reclaim ethanol under reduced pressure, and concentrate the remaining liquid to a relative density of 1.25 The thick paste was dried under reduced pressure to obtain 450 g of turmeric ethanol extract.

Embodiment 3

[0091] Embodiment 3 of the present invention: the preparation of turmeric petroleum ether extract:

[0092] After pulverizing 10 kg of dried turmeric rhizomes, heat and reflux extraction with petroleum ether, extract 3 times with 40 L of petroleum ether each time, combine the extracts, and evaporate under reduced pressure to obtain 310 g of petroleum ether extract.

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PUM

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Abstract

The present invention is one kind of curcuma extract and its preparation process, medicine composition and use. The curcuma extract is produced with fresh curcuma rhizome, and through air drying, crushing to obtain curcuma powder, heating reflux or percolating extract for 2-4 times with organic solvent and / or water, and concentrating and drying the extracted liquid. The curcuma extract has obviousfunctions of inhibiting platelet aggregation caused by collagen and adrenaline, diminishing inflammation, lowering blood fat, antagonizing tumor, protecting gastric mucous membrane, antagonizing early pregnancy and benefiting gall bladder. It has certain treating effect on some cardiovascular system diseases, gynecologic diseases, surgical diseases and autoimmune diseases.

Description

Technical field: [0001] The invention relates to a turmeric extract, a preparation method thereof, a pharmaceutical composition and application thereof, and belongs to the technical field of medicines. Background technique: [0002] Turmeric (Curcuma longa L.) is the dry rhizome of ginger plant Curcuma longa. It is a unique and commonly used medicine in Southwest China and has a long history of medicinal use. According to the Miao people's folk medicine experience, its rhizome can be used medicinally, and has the functions of breaking blood and promoting Qi, stimulating menstruation and relieving pain. Turmeric can be used alone or in combination. In Miao people, turmeric is compatible with Phellodendron 90, raw rhubarb, angelica, trichosanthum officinalis, magnolia officinalis, tangerine peel, licorice, raw turmeric, raw southern star, etc., and is mainly used to treat muscle soreness, joint redness and pain, and flexion and extension caused by rheumatism. [0003] At pre...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P9/00A61P37/02A61P19/04A61P43/00
Inventor 周欣陈华国赵超李明
Owner GUIZHOU NORMAL UNIVERSITY
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