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Effervescence tablet for cold

A technology for effervescent tablets and midday tea, which is applied in drug delivery, pill delivery, plant raw materials, etc., and can solve problems such as increasing costs, limiting the application of effervescent agents in traditional Chinese medicine, production, transportation, carrying, and inconvenient use

Inactive Publication Date: 2009-11-04
JIANGXI HERBFINE HI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

When traditional Chinese medicine is made into an effervescent dosage form, water extraction and alcohol extraction are usually used to obtain a variety of mixed macromolecular effective substances, including pectin, sugars, polysaccharides and other viscous substances. The disintegration is affected by viscous substances, and the disintegration is slow. On the other hand, in order to ensure the curative effect, the single-tablet Chinese medicine effervescent dosage form is taken in a large amount, which also affects the disintegration speed. In order to ensure disintegration, the excipients have to be increased The dosage makes some effervescent tablets need to be 4-5g / tablet, which not only increases the cost, but also brings inconvenience to production, transportation, carrying and use
The disintegration speed of traditional Chinese medicine effervescent preparations is as long as several minutes, and the advantages are not prominent compared with traditional Chinese medicine granules, which limits the application of traditional Chinese medicine effervescent preparations

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] 1. Preparation of afternoon tea extract: Take 30 parts of Atractylodes atractylodes, 30 parts of Bupleurum, 30 parts of Notopterygium, 30 parts of Fangfeng, 30 parts of Angelica dahurica, 30 parts of Chuanxiong, 30 parts of Patchouli, 30 parts of Peucedanum, and 30 parts of Forsythia , 30 parts of tangerine peel, 30 parts of hawthorn, 30 parts of citrus aurantium, 45 parts of malt (stir-fried), 30 parts of licorice, 45 parts of bellflower, 30 parts of Liushenqu (fried), 45 parts of perilla leaves, 45 parts of Magnolia officinalis, 960 parts of black tea share. Cangzhu, Bupleurum, Notopterygium, Fangfeng, Angelica dahurica, Chuanxiong, Patchouli, Forsythia, Peucedanum, Tangerine Peel, Citrus Aurantium, Perilla Leaf, Magnolia officinalis extract volatile oil, and the distilled aqueous solution is collected separately; medicinal residues and hawthorn, etc. Six flavors, add water and decoct twice, the first time for 2 hours, the second time for 1 hour, combine the decoction...

Embodiment 2

[0066] 1. Preparation of Noon Tea Extract: Same as Example 1.

[0067] 2. Noon tea ring-shaped effervescent tablets (100 tablets)

[0068] Formula ratio:

[0069] Afternoon Tea Extract 85g Tartaric Acid 168g

[0070] Cyclamate 5g essence 2g

[0071] Sodium bicarbonate 80g PEG 40005g

[0072] Microcrystalline Cellulose 30g PVP 25g

[0073] 3. Preparation method

[0074] The afternoon tea extract obtained by spray drying is sealed and stored for later use; the tartaric acid, sodium bicarbonate, and microcrystalline cellulose are respectively crushed through a 100-mesh sieve, and sealed and stored for later use; cyclamate and essence are crushed through a 100-mesh sieve, and PEG 4000 is crushed through a 140-mesh sieve Mesh sieve; during the preparation process, control the environmental temperature of the preparation at 25°C and the humidity below 45%; mix the afternoon tea extract and tartaric acid evenly according to the required proportion, then add cyclamate and essence...

Embodiment 3

[0077] 1. Preparation of Noon Tea Extract: Same as Example 1.

[0078] 2. Prepare Noon Tea Annular Effervescent Tablets (100 tablets)

[0079] Formula ratio:

[0080] Afternoon tea extract 55g, malic acid 40g, citric acid 115g

[0081]Aspartame 5g Acesulfame K 3g Flavor 2g

[0082] Sodium bicarbonate 40g Potassium carbonate 90g

[0083] Cross-linked polyvinylpyrrolidone 35g Magnesium stearate 15g

[0084] 3. Preparation method

[0085] The afternoon tea extract obtained by spray drying is sealed and stored for later use; malic acid, citric acid, sodium bicarbonate, potassium carbonate, and cross-linked polyvinylpyrrolidone are respectively pulverized through a 100-mesh sieve, and sealed and stored for later use; acesulfame potassium and essence are pulverized 100-mesh sieve, magnesium stearate is crushed through a 140-mesh sieve; during the preparation process, the ambient temperature of the formulation is controlled at 25°C and the humidity is below 45%; the afternoon te...

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Abstract

The invention relates to an effervescence tablet for treating common cold, wherein the raw materials include atractylodes rhizome, Bupleurum root, notopterygium root, ledebouriella root, dahurian angelica root, Ligusticum wallichii, patchouli, peucedanum root, capsule of weeping forsythia, dried orange peel, haw, immature bitter orange, malt, licorice root, root of ballon flower, medicated leaven, purple perilla, magnolia bark and black tea.

Description

technical field [0001] The invention relates to the technical field of Chinese patent medicine effervescent tablets, in particular to afternoon tea effervescent tablets. Background technique [0002] At present, the main effervescent tablets in my country are health care products, such as vitamin C, calcium supplement effervescent tablets, and effervescent tablets for gynecological external use, such as Jieeryin effervescent tablets, metronidazole vaginal effervescent tablets, etc. But oral Chinese medicine effervescent preparations are less. And making afternoon tea formula the effervescent tablet of oral pure Chinese medicine preparation, seldom report. In addition, annular tablets have been used in the food industry for a long time, but they are rarely used in the field of medicine, especially in the field of effervescent tablet preparation, and there are few reports. [0003] Traditional Chinese medicine effervescent tablet is a new dosage form, which has the advantages...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/46A61K9/20A61K36/899A61P1/14A61P1/08
Inventor 罗晓健王跃生吕爱平饶毅王金钱游剑张爱玲
Owner JIANGXI HERBFINE HI TECH
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