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Buccal tablet of Asraguluspolysacharin

A technology of astragalus polysaccharide and buccal tablets, which is applied to medical preparations containing active ingredients, allergic diseases, metabolic diseases, etc., can solve problems such as no reports of astragalus polysaccharide buccal tablets, and achieve great application and development value. Good taste and the effect of improving absorption and utilization

Inactive Publication Date: 2009-06-24
SHANDONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After searching, although there are reports on the study of astragalus polysaccharides, there is no report on the buccal tablets of astragalus polysaccharides and its preparation

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Astragalus polysaccharide lozenges:

[0035] In parts by weight, the unit is kilogram, weighed respectively: 80 parts of astragalus polysaccharide, 418 parts of xylitol, 355 parts of lactose, 83 parts of microcrystalline cellulose, 52 parts of starch, 6 parts of magnesium stearate, 1.0 part of menthol , 4.7 parts of citric acid, 0.3 parts of sodium essence.

[0036] Mix the above-mentioned astragalus polysaccharides (required to reach a fineness of 400 mesh), xylitol, lactose, microcrystalline cellulose, and starch, and evenly moisten it with water. Pass the wetted mixture through a 16-22 mesh sieve and dry it, then sieve it, and dry it. Granules, add magnesium stearate, menthol, citric acid, sodium essence, and then compress the mixture into tablets, each tablet weighs 250 mg, and the active ingredient astragalus polysaccharide content is 20 mg.

Embodiment 2

[0038] Astragalus polysaccharide lozenges:

[0039] In parts by weight, the unit is kilogram, respectively weigh: 20 parts of astragalus polysaccharide, 440 parts of xylitol, 380 parts of lactose, 90 parts of microcrystalline cellulose, 55 parts of starch, 7 parts of magnesium stearate, 1.5 parts of menthol , 6 parts of citric acid, 0.5 part of essence sodium.

[0040] Mix the above-mentioned astragalus polysaccharides (required to reach a fineness of 400 mesh), xylitol, lactose, microcrystalline cellulose, and starch, and evenly moisten it with water. Pass the wetted mixture through a 16-22 mesh sieve and dry it, then sieve it, and dry it. Granules, add magnesium stearate, menthol, citric acid, sodium essence, then compress the mixture into tablets, each tablet weighs 250 mg, and the active ingredient astragalus polysaccharide content is 5 mg.

Embodiment 3

[0042] Astragalus polysaccharide lozenges:

[0043] In parts by weight, the unit is kilogram, respectively weighed: 120 parts of astragalus polysaccharide, 400 parts of xylitol, 340 parts of lactose, 80 parts of microcrystalline cellulose, 50 parts of starch, 5 parts of magnesium stearate, 0.5 parts of menthol , 4.3 parts of citric acid, 0.2 parts of sodium essence.

[0044] Mix the above-mentioned astragalus polysaccharide (required fineness reaches 400 mesh), xylitol, lactose, microcrystalline cellulose, and starch, and evenly moisten it with water, pass the wetted mixture through a 16-22 mesh sieve and dry it, then sieve it, and dry it. Add magnesium stearate, menthol, citric acid, sodium essence, and then compress the mixture into tablets, each tablet weighs 250 mg, and the active ingredient astragalus polysaccharide content is 30 mg.

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PUM

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Abstract

The invention discloses an astragalus polysaccharide buccal tablet, which contains 2%-12% by weight of astragalus polysaccharide and the rest of a pharmaceutically acceptable carrier for the buccal tablet. The astragalus polysaccharide of the present invention has the characteristics of being easy to take and having a good taste; it can be directly absorbed through the oral mucosa, avoiding the loss of nutrients when the nutrients are absorbed through organs such as the human body's gastrointestinal tract and liver, and improving the absorption of nutrients in the astragalus polysaccharides Utilization rate is of great value to clinical treatment and health care prevention.

Description

technical field [0001] The invention relates to a polysaccharide buccal tablet, in particular to an astragalus polysaccharide buccal tablet and a preparation method thereof. Background technique [0002] Radix Astragali (Radix Astragali), also known as Mianhuangqi, English MilkvetchRoot, is the root of the leguminous plant Astragalus membranaceus Bge.var.mongholicus (Bge.) Hsiao. Astragalus membranaceus has the functions of invigorating qi and consolidating the surface, detoxifying and discharging pus, diuretic, astringing sores and promoting granulation; it is often used clinically for qi deficiency and fatigue, chronic diarrhea and prolapse of the anus, spontaneous sweating, edema, prolapse of the genitals, chronic nephritis, proteinuria, diabetes, and chronic sores. Diseases such as non-healing. [0003] In recent decades, it has been found that polysaccharides extracted from plants have very important and special physiological activities. These polysaccharides particip...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/715A61K36/481A61K9/20A61K47/38A61P39/06A61P37/02A61P9/00A61P9/12A61P3/10A61K125/00
Inventor 常宏文张尚立高延秀马剑锋张海龙
Owner SHANDONG UNIV
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