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Medicine for treating woman's dysmenorrhea and preparing process thereof

A medicine and a technology for dysmenorrhea, applied in the field of medicines for treating women's dysmenorrhea and their preparation, can solve the problems of failing to give full play to the multi-target comprehensive effects and single effects of traditional Chinese medicine compounds, and achieve the effects of no toxic side effects and reduced dosage.

Inactive Publication Date: 2007-10-24
SHANGHAI JIAO TONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are also single-medicine preparations such as Futongning Dropping Pills. Because it is a single-medicine and has a single effect, it fails to give full play to the advantages of the multi-target comprehensive effect of the traditional Chinese medicine compound.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The medicinal ingredients are made of the following raw materials (percentage by weight): 70% of angelica, 20% of corydalis and 10% of cinnamon.

[0020] preparation:

[0021] 1. Crush the medicinal materials of Angelica sinensis through a 40-mesh sieve, soak in water for 4 hours, and steam distill for 4 hours to obtain Angelica sinensis oil for later use;

[0022] 2. Crush the cinnamon medicinal material through a 40-mesh sieve, place it in a supercritical CO2 extractor, extract at 40°C and 20MPa for 2 hours, and obtain cinnamon oil for later use;

[0023] 3. Crush the medicinal material of Corydalis Corydalis through a 40-mesh sieve, heat and extract with 70% ethanol at 50°C for 3 hours under reflux, filter with suction, evaporate the solvent, dissolve with sulfuric acid solution with a pH value of 3-4, filter, and pass the filtrate through cation exchange resin column. The cation exchange resin was basified with ammonia water, rinsed with 70% ethanol, and the eluat...

Embodiment 2

[0027] The medicinal ingredients are made of the following raw materials (percentage by weight): 43% of angelica, 43% of corydalis and 14% of cinnamon.

[0028] preparation:

[0029] 1. Crush the medicinal materials of Angelica sinensis through a 40-mesh sieve, soak in water for 4 hours, and steam distill for 4 hours to obtain Angelica sinensis oil for later use;

[0030] 2. Crush the cinnamon medicinal material through a 40-mesh sieve, soak in water for 4 hours, and steam distillation for 4 hours to obtain cinnamon oil for later use;

[0031] 3. Crush the medicinal material of Corydalis Corydalis through a 40-mesh sieve, soak in sulfuric acid solution with a pH value of 3-4 for 12 hours, filter, adjust the pH value of the filtrate to neutral with ammonia water, and add it to the macropore treated according to the instructions. On the adsorption resin column, first use about 3 times the amount of deionized water to elute, then use 5 times the amount of 50% ethanol to elute, c...

Embodiment 3

[0035] The medicinal ingredients are made of the following raw materials (percentage by weight): 16% of Angelica sinensis, 66% of Corydalis Corydalis, and 18% of cinnamon.

[0036] preparation:

[0037] 1. Crush the medicinal materials of Angelica sinensis through a 40-mesh sieve, place in a supercritical CO2 extractor, extract at 40°C and 25MPa for 3 hours, and obtain Angelica sinensis oil for later use;

[0038] 2. Crush the cinnamon medicinal material through a 40-mesh sieve, place it in a supercritical CO2 extractor, extract at 40°C and 20MPa for 2 hours, and obtain cinnamon oil for later use;

[0039] 3. Crush the medicinal material of Corydalis Corydalis through a 40-mesh sieve, extract with 70% ethanol at 50°C for 3 hours under reflux, filter with suction, evaporate the solvent, dissolve with sulfuric acid solution with a pH value of 3-4, filter, and pass the filtrate through a cation exchange resin column. Alkalinize the cation exchange resin with ammonia water, rins...

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PUM

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Abstract

The invention provides a medicine for treating woman's dysmenorrhea and preparing process, which comprises Chinese angelica root 16-70%, corydalis ambigua 20-66%, Cinnamomum cassia 10-18%. And the preparing process comprises the following steps, charging angelica oil, Cinnamomum cassia oil and corydalis ambigua total alkali into the mixed solution of water bath heated molten drop pill base materials, homogenizing the mixed solution through stirring, loading into thermal insulation tank of the drop pill making machine, dropping under the condition of 70-90 deg. C, instilling into glass condensation column containing 0 deg. C dimethyl silicon oil, modeling and taking out, removing adhered dimethyl silicon oil with oil absorbent paper.

Description

technical field [0001] The invention relates to a medicine in the technical field of medicine and a preparation method thereof, in particular to a medicine for treating women's dysmenorrhea prepared from traditional Chinese medicines angelica, cinnamon and corydalis as raw materials and a preparation method thereof. Background technique [0002] Dysmenorrhea refers to cramping pain in the lower abdomen and waist before and during menstruation, accompanied by nausea, vomiting, and cold extremities in severe cases. Dysmenorrhea is one of gynecological common diseases. According to data, the incidence rate of dysmenorrhea among Chinese women is 33.1%. Traditional Chinese medicine refers to dysmenorrhea as abdominal pain due to menstrual fluid, abdominal pain during menstruation, and abdominal pain during menstruation. Pain, or Chong Ren, the uterus lost in nourishment, disgrace is also pain. Modern medical research generally believes that dysmenorrhea is mainly related to fa...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/66A61K36/54A61K36/232A61K9/20A61P15/00A61P29/00
Inventor 邱明丰贾伟刘金星王小荣赵爱华
Owner SHANGHAI JIAO TONG UNIV
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