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73results about How to "Has broad-spectrum antiviral effect" patented technology
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Recombinant bovine long-term interferon alpha and fusion protein for preparing long-term interferon and its preparation method
InactiveCN107266587AExtended half-lifeHigh expressionBacteriaMicroorganism based processesDepot PreparationsPegylated interferon α
The invention discloses a recombinant bovine peginterferon α, a fusion protein for preparing the peginterferon and a preparation method thereof. The fusion protein is formed by connecting bovine interferon γ and bovine interferon α through a flexible linker, and the fusion protein is connected with bovine interferon α. After the lyoprotectant is mixed, the recombinant bovine peginterferon α can be obtained by lyophilization. The recombinant bovine long-acting interferon alpha can significantly increase the half-life of bovine interferon, which is more than 11 times higher than that of common bovine interferon, has broad-spectrum antiviral effect and can improve the immune response of cattle itself.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Goat albumin-interferon tau-interleukin 2 fused protein, preparation method and encoding gene thereof and goat long-acting interferon
InactiveCN107253996AExtended half-lifeHigh expressionBacteriaMicroorganism based processesHalf-lifeInterleukin II
The invention discloses ovine albumin-interferon τ-interleukin-2 fusion protein, a preparation method and its coding gene, a kind of ovine long-acting interferon, and ovine albumin, ovine interferon τ and ovine interleukin-2 are connected through a flexible linker , obtain ovine albumin-interferon τ-interleukin-2 fusion protein, design and optimize its coding gene, and finally prepare recombinant ovine long-acting interferon, which can significantly increase the half-life of ovine interferon, which is 17 times longer than that of ordinary ovine interferon Above, and has broad-spectrum antiviral effect and can improve the immune response of sheep itself.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Fusion protein comprising pig albumin and pig interferon gamma, preparation method of fusion protein, and recombination pig long-acting interferon gamma
InactiveCN108840938AExtended half-lifeLow costBacteriaAntibody mimetics/scaffoldsAnimal scienceHalf-life
The invention discloses a fusion protein comprising a pig albumin and a pig interferon gamma, a preparation method of the fusion protein, and a recombination pig long-acting interferon gamma. The fusion protein is formed by connecting the pig albumin and the pig interferon gamma through a flexible linker, and the recombination pig long-acting interferon gamma is obtained by blending the fusion protein and a freezing and drying protecting agent, and freeze-drying. The recombination pig long-acting interferon gamma obviously improves the half-life period of the pig interferon, the half-life period is improved by 15 times or more in comparison with the common pig interferon gamma, the recombination pig long-acting interferon gamma has a broad-spectrum antiviral effect, and the immune responseof the pig is improved.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD +1
Porcine albumin-interferon alpha-interleukin 2 fusion protein, preparation method as well as coding gene thereof, and porcine pegylated interferon
InactiveCN108840945AExtended half-lifeLow costBacteriaMicroorganism based processesInterleukin IIInterleukin-2 Fusion Protein
The invention discloses a porcine albumin-interferon alpha-interleukin 2 fusion protein, a preparation method as well as a coding gene thereof, and porcine pegylated interferon. Porcine albumin, porcine interferon alpha and porcine interleukin 2 are connected through a flexible linker to obtain the porcine albumin-interferon alpha-interleukin 2 fusion protein, the coding gene of the fusion proteinis designed to be optimized, and the recombinant porcine pegylated interferon is prepared finally; the porcine pegylated interferon can significantly improve a half-life period of porcine interferon,which is 27 times or more than 27 times of the half-life period of ordinary porcine interferon, has a broad-spectrum antiviral effect, and can improve the immune response of pigs themselves.
Owner:ANHUI JIUCHUAN BIOTECH
Canine albumin-interferon alpha-interleukin 2 fusion protein, preparation method and coding gene thereof, and canine long-acting interferon
InactiveCN108840946AExtended half-lifeLow costBacteriaMicroorganism based processesLong actingHalf-life
The invention discloses a canine albumin-interferon alpha-interleukin 2 fusion protein, a preparation method thereof and a coding gene thereof, and a canine long-acting interferon. Canine albumin, canine interferon alpha and canine interleukin 2 are connected by a flexible linker to obtain the canine albumin-interferon alpha-interleukin 2 fusion protein. The coding gene of the fusion protein is designed and optimized to finally obtain a recombinant canine long-acting interferon, which can significantly prolong the half-life of the canine interferon by more than 18 times in comparison with a common canine interferon, has a broad-spectrum antiviral effect and can improve the immune response of dogs.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Pig albumin-interferon alpha-interleukin 2 fusion protein as well as preparation method and encoding gene thereof, and long-acting interferon
InactiveCN107383205AExtended half-lifeHigh expressionBacteriaMicroorganism based processesLong actingHalf-life
The invention discloses pig albumin-interferon alpha-interleukin 2 fusion protein as well as a preparation method and an encoding gene thereof, and pig long-acting interferon. The pig albumin-interferon alpha-interleukin 2 fusion protein is obtained by connecting pig albumin, pig interferon alpha and pig interleukin 2 through a flexible linker, the encoding gene of the pig albumin-interferon alpha-interleukin 2 fusion protein is designed and optimized, and the recombinant pig long-acting interferon is finally prepared, so that the half-life period of the pig interferon can be prolonged obviously, the half-life period is prolonged by 27 times or above compared with that of the common pig interferon, the broad-spectrum antiviral action is achieved, and the autoimmune response of the pigs can be improved.
Owner:ANHUI JIUCHUAN BIOTECH
Recombinant bovine long-acting interferon as well as fusion protein preparing long-acting interferon as well as preparation method of fusion protein
The invention discloses a recombinant bovine long-acting interferon as well as a fusion protein preparing the long-acting interferon as well as a preparation method of the fusion protein. The fusion protein is formed by connecting bovine interleukin 2 and bovine interferon alpha by virtue of flexible linker, after the fusion protein is mixed with a freeze drying protection agent, the mixture is freeze dried, thus the recombinant bovine long-acting interferon is obtained. By adopting the recombinant bovine long-acting interferon, the half-life period of the bovine interferon can be significantly prolonged and can be increased by 10 times or more compared with the half-life period of the ordinary bovine interferon, a broad-spectrum antivirus effect can be achieved, and the immune response ofthe cattle can be improved.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Fusion protein formed by sheep albumin and sheep interferon gamma and preparation method of fusion protein and recombinant sheep long-term interferon gamma
InactiveCN107254000AExtended half-lifeHigh expressionBacteriaMicroorganism based processesHalf-lifeInterferon alpha
The invention discloses a fusion protein composed of ovine albumin and ovine interferon gamma, a preparation method thereof and a recombinant ovine long-acting interferon gamma. The fusion protein is composed of ovine albumin and ovine interferon gamma through a flexible linker The recombinant sheep peginterferon gamma can be obtained after mixing the fusion protein with the freeze-drying protective agent and freeze-drying. The recombinant sheep long-acting interferon gamma can significantly increase the half-life of sheep interferon, which is more than 12 times higher than that of ordinary sheep interferon gamma, has broad-spectrum antiviral effect and can improve the immune response of sheep itself.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Bovine albumin-interferon alpha-interleukin 2 fusion protein, preparation method and coding gene thereof, and bovine long-acting interferon
InactiveCN108840947AExtended half-lifeLow costBacteriaMicroorganism based processesAgricultural scienceHalf-life
The invention discloses a bovine albumin-interferon alpha-interleukin 2 fusion protein, a preparation method and a coding gene thereof, and a bovine long-acting interferon. Bovine albumin, bovine interferon alpha and bovine interleukin 2 are connected by a flexible linker to obtain the bovine albumin-interferon alpha-interleukin 2 fusion protein. The coding gene of the fusion protein is designed and optimized to finally obtain a recombinant bovine long-acting interferon, which can significantly prolong the half-life of the bovine interferon by more than 20 times in comparison with a common bovine interferon, has a broad-spectrum antiviral effect and can improve the immune response of cattle.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Broad-spectrum antiviral bactericidal plastic and application thereof
InactiveCN111363270AAvoid infectionGood for healthBiocideFungicidesBiotechnologyIsomaltooligosaccharide
The invention relates to broad-spectrum antiviral bactericidal plastic and application thereof. The bactericidal plastic is prepared from following components in percentage by weight: 90-96% of basicresin, 1-3% of a modified antibacterial agent, and 0-10% of a plastic additive, wherein the modified antibacterial agent is prepared from the following components in parts by weight: 5 to 15 parts ofchlorophyll, 5 to 15 parts of tea polyphenol, 8 to 16 parts of taurine, 0.5 to 2 parts of citric acid, 6 to 18 parts of isomalto-oligosaccharide, 0.6 to 1.5 parts of yeast powder, 4 to 10 parts of chitosan, 30 to 50 parts of nano titanium dioxide, 3 to 8 parts of zinc oxide and 3 to 8 parts of ultraviolet fluorescent powder. The broad-spectrum antiviral bactericidal plastic has a broad-spectrum antiviral effect, can kill viruses and bacteria for a long time, effectively prevents virus infection possibly caused by frequent contact between users and plastic cards such as bank cards and identitycards, and is beneficial to the health of the users.
Owner:IDEAL NEW MATERIAL TECH HONGKONG LTD
Fusion protein consisting of pig albumin, pig interferon gamma and pig interferon alpha and preparation method thereof
InactiveCN108840951AExtended half-lifeLow costBacteriaMicroorganism based processesHalf-lifeInterferon alpha
The invention discloses a fusion protein consisting of pig albumin, pig interferon gamma and pig interferon alpha and a preparation method thereof. The fusion protein is formed by connecting the pig albumin, pig interferon gamma and pig interferon alpha through a flexible linker, and a recombinant pig long-acting interferon can be obtained through freeze drying after the fusion protein is compounded with a freeze-drying protective additive. The recombinant pig long-acting interferon can obviously improve the half-life period of the pig interferon, the half-life period of the pig interferon isprolonged by more than 24 times by compared with that of common pig interferon, the fusion protein has a broad-spectrum antiviral role, and the immune response of pigs can be improved.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Fusion protein with porcine albumin, porcine interferons gamma and porcine interleukins 2 and method for preparing fusion protein
InactiveCN107365390AExtended half-lifeHigh expressionBacteriaMicroorganism based processesHalf-lifeInterferon alpha
The invention discloses a fusion protein composed of porcine albumin, porcine interferon gamma and porcine interleukin 2 and a preparation method thereof. The fusion protein is composed of porcine albumin, porcine interferon gamma and porcine interleukin 2 through a flexible linker The recombinant porcine peginterferon can be obtained after the fusion protein is mixed with a freeze-drying protective agent and freeze-dried. The recombinant porcine long-acting interferon can significantly increase the half-life of porcine interferon, which is more than 23 times higher than that of common porcine interferon, has broad-spectrum antiviral effect and can improve the immune response of pigs themselves.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Fusion protein consisting of chicken albumin, chicken interferon gamma and chicken interferon alpha and preparation method thereof
The invention discloses a fusion protein consisting of chicken albumin, chicken interferon gamma and chicken interferon alpha and a preparation method thereof. The fusion protein is formed by connecting the chicken albumin, chicken interferon gamma and chicken interferon alpha through a flexible linker, and a recombinant chicken long-acting interferon can be obtained through freeze drying after the fusion protein is compounded with a freeze-drying protective additive. The recombinant chicken long-acting interferon can obviously improve the half-life period of the chicken interferon, the half-life period of the chicken interferon is prolonged by more than 22 times by compared with that of common chicken interferon, the fusion protein has a broad-spectrum antiviral role, and the immune response of chickens can be improved.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Recombinant pegylated interferon for dogs, fusion protein for preparation of recombinant pegylated interferon and preparation method of recombinant pegylated interferon
InactiveCN107337738AExtended half-lifeHigh expressionBacteriaAntibody mimetics/scaffoldsDepot PreparationsHalf-life
The invention discloses a recombinant canine peginterferon, a fusion protein for preparing the peginterferon and a preparation method thereof. The fusion protein is formed by connecting canine interleukin 2 and canine interferon α through a flexible linker. The recombinant canine peginterferon can be obtained after the protein is mixed with the freeze-drying protective agent and freeze-dried. The recombinant canine peginterferon can significantly increase the half-life of canine interferon, which is more than 10 times higher than that of ordinary canine interferon, has broad-spectrum antiviral effect and can improve the immune response of canine itself.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Fusion protein prepared from canine albumin and canine interferon gamma as well as preparation method thereof and recombinant canine pegylated interferon gamma
The invention discloses fusion protein prepared from canine albumin and canine interferon gamma as well as a preparation method thereof and a recombinant canine pegylated interferon gamma. The fusionprotein is prepared from the canine albumin and the canine interferon gamma through flexible linker connection, and the fusion protein and a freeze-drying protective additive are mixed and freeze dried to obtain the recombinant canine pegylated interferon gamma. The recombinant canine pegylated interferon gamma can obviously improve a half-life period of the canine interferon; compared with ordinary canine interferon gamma, the half-life period of the canine interferon is improved by 13 times or more; furthermore, the recombinant canine pegylated interferon gamma has a broad-spectrum antiviraleffect and can improve canine self immune response.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Recombinant canine long-acting interferon alpha, fusion protein for preparing long-acting interferon, and preparation method of fusion protein
InactiveCN107383207AExtended half-lifeHigh expressionBacteriaMicroorganism based processesAnti virusHalf-life
The invention discloses recombinant canine long-acting interferon alpha, fusion protein for preparing the long-acting interferon, and a preparation method of the fusion protein. The fusion protein is formed by connecting canine interferon gamma and canine interferon alpha through flexible linker, and the fusion protein is blended with a lyoprotectant and then is freeze-dried so as to obtain the recombinant canine long-acting interferon alpha. The recombinant canine long-acting interferon alpha can remarkably prolong the half-life period of the canine interferon and prolongs the half-life period by 11 times or more compared with common canine interferon, has a broad-spectrum anti-virus effect, and improves the immune response of the canine.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Fusion protein composed of sheep albumin, interferon Tau and interleukin 2, preparation method thereof and its coding gene, and sheep long-acting interferon
InactiveCN108822220AExtended half-lifeLow costBacteriaMicroorganism based processesHalf-lifeInterleukin II
The invention discloses a fusion protein composed of sheep albumin, interferon Tau and interleukin 2, a preparation method thereof and its coding gene, and sheep long-acting interferon. The fusion protein is linked by sheep albumin, sheep interferon Tau and sheep interleukin 2 through a flexible linker, the fusion protein of sheep albumin, interferon Tau and interleukin 2 is obtained, its coding gene is designed and optimized, and recombinant sheep long-acting interferon is finally prepared. The recombinant sheep long-acting interferon can obviously increase half life of sheep interferon, thehalf life is increased by more than 17 times by comparing with that of common sheep interferon, and the recombinant sheep long-acting interferon has wide spectrum antiviral effect and increases the sheep self immune response.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Fusion protein consisting of pig interleukin 2, pig interferon gamma and pig interferon alpha and preparation method thereof
InactiveCN108840950AExtended half-lifeLow costBacteriaAntibody mimetics/scaffoldsHalf-lifeInterleukin II
The invention discloses a fusion protein consisting of pig interleukin 2, pig interferon gamma and pig interferon alpha and a preparation method thereof. The fusion protein is formed by connecting thepig interleukin 2, pig interferon gamma and pig interferon alpha through a flexible linker, and a recombinant pig long-acting interferon can be obtained through freeze drying after the fusion proteinis compounded with a freeze-drying protective additive. The recombinant pig long-acting interferon can obviously improve the half-life period of the pig interferon, the half-life period of the pig interferon is prolonged by more than 24 times by compared with that of common pig interferon, the fusion protein has a broad-spectrum antiviral role, and the immune response of pigs can be improved.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Fusion protein composed of bovine albumin, bovine interferon gamma and bovine interferon alpha and preparation method thereof
InactiveCN108794645AExtended half-lifeLow costBacteriaMicroorganism based processesHalf-lifeBovine serum albumin
The invention discloses fusion protein composed of bovine albumin, bovine interferon gamma and bovine interferon alpha and a preparation method thereof. The fusion protein is formed by conducting flexible linker connection on the bovine albumin, the bovine interferon gamma and the bovine interferon alpha, and after the fusion protein and a freeze-drying protective additive are mixed, through freeze drying, recombinant bovine pegylated interferon can be obtained. A half-life period of the recombinant bovine pegylated interferon is significantly improved, compared with the half-life period of ordinary bovine interferon, the half-life period of the recombinant bovine pegylated interferon is improved by 18 times or more, and the recombinant bovine pegylated interferon has a broad-spectrum antiviral effect and can improve immune response of bovine.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Fusion protein consisting of sheep interleukin 2, sheep interferon gamma and sheep interferon tau and preparation method thereof
InactiveCN108840953AExtended half-lifeLow costBacteriaPeptide/protein ingredientsHalf-lifeInterferon alpha
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Fused protein composed of chicken albumin, chicken interferon gamma and chicken interleukin 2 and preparation method of fused protein
InactiveCN107383202AExtended half-lifeHigh expressionBacteriaMicroorganism based processesAnti virusHalf-life
The invention discloses a fusion protein composed of chicken albumin, chicken interferon gamma and chicken interleukin 2 and a preparation method thereof. The fusion protein is composed of chicken albumin, chicken interferon gamma and chicken interleukin 2. Formed by flexible linker connection, the fusion protein is mixed with a lyoprotectant and freeze-dried to obtain the recombinant chicken peginterferon. The recombinant chicken long-acting interferon can significantly increase the half-life of chicken interferon, which is more than 21 times higher than that of common chicken interferon, has broad-spectrum antiviral effect and can improve the immune response of chicken itself.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Fusion protein consisting of porcine albumin, porcine interferon gamma and porcine interferon alpha and preparation method of fusion protein
InactiveCN107353347AExtended half-lifeHigh expressionBacteriaMicroorganism based processesBroad spectrumInterferon
The invention discloses a fusion protein composed of porcine albumin, porcine interferon γ and porcine interferon α and a preparation method thereof. The fusion protein is composed of porcine albumin, porcine interferon γ and porcine interferon α through a flexible linker The recombinant porcine peginterferon can be obtained after the fusion protein is mixed with a freeze-drying protective agent and freeze-dried. The recombinant porcine long-acting interferon can significantly increase the half-life of porcine interferon, which is more than 24 times higher than that of ordinary porcine interferon, has broad-spectrum antiviral effect and can improve the immune response of pigs themselves.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Fusion protein prepared from ovine albumin, ovine interferon gamma and ovine interferon tau and preparation method for fusion protein
InactiveCN107245110AExtended half-lifeHigh expressionBacteriaMicroorganism based processesHalf-lifeInterferon alpha
The invention discloses a fusion protein composed of ovine albumin, ovine interferon γ and ovine interferon τ and a preparation method thereof. The fusion protein is composed of ovine albumin, ovine interferon γ and ovine interferon τ through a flexible linker The recombinant sheep peginterferon can be obtained by lyophilizing after the fusion protein is mixed with the lyoprotectant. The recombinant sheep long-acting interferon can significantly increase the half-life of sheep interferon, which is more than 17 times higher than that of ordinary sheep interferon, has broad-spectrum antiviral effect and can improve the immune response of sheep itself.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Fusion protein composed of chicken albumin, chicken interferon gamma and chicken interferon alpha and preparation method thereof
InactiveCN107286255AExtended half-lifeHigh expressionBacteriaMicroorganism based processesHalf-lifeInterferon alpha
The invention discloses a fusion protein composed of chicken albumin, chicken interferon gamma and chicken interferon alpha and a preparation method thereof. The fusion protein is composed of chicken albumin, chicken interferon gamma and chicken interferon alpha through a flexible linker The recombinant chicken peginterferon can be obtained after the fusion protein is mixed with the freeze-drying protective agent and freeze-dried. The recombinant chicken long-acting interferon can significantly increase the half-life of chicken interferon, which is more than 22 times higher than that of common chicken interferon, has broad-spectrum antiviral effect and can improve the immune response of chicken itself.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Recombinant ovine pegylated interferon tau, fusion protein for preparing same and preparation method of fusion protein
InactiveCN107353348AExtended half-lifeHigh expressionBacteriaAntibody mimetics/scaffoldsHalf-lifeProtective Agents
The invention discloses recombinant ovine pegylated interferon tau, fusion protein for preparing the same and a preparation method of the fusion protein. The fusion protein is formed by connecting sheep interferon gamma and sheep interferon tau through a flexible linker, and the recombinant sheep pegylated interferon tau can be obtained from the fusion protein and a freeze-drying protective agent through mixing and freeze-drying. The recombinant sheep pegylated interferon tau can significantly prolong the half-life of the sheep interferon, the half-life is prolonged 10 times or higher compared with that of normal sheep interferon, and the recombinant sheep pegylated interferon tau has a broad-spectrum antiviral effect and can improve immune response of sheep.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Fusion protein composed of bovine interleukin 2, bovine interferon gamma and bovine interferon alpha and preparation method thereof
InactiveCN108794644AExtended half-lifeLow costBacteriaAntibody mimetics/scaffoldsFreeze-dryingWhite blood cell
The invention discloses fusion protein composed of bovine interleukin 2, bovine interferon gamma and bovine interferon alpha and a preparation method thereof. The fusion protein is formed by conducting flexible linker connection on the bovine interleukin 2, the bovine interferon gamma and the bovine interferon alpha, and after the fusion protein and a freeze-drying protective additive are mixed, through freeze drying, recombinant bovine pegylated interferon can be obtained. A half-life period of the recombinant bovine pegylated interferon is significantly improved, compared with the half-lifeperiod of ordinary bovine interferon, the half-life period of the recombinant bovine pegylated interferon is improved by 16 times or more, and the recombinant bovine pegylated interferon has a broad-spectrum antiviral effect and can improve immune response of bovine.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Fused protein composed of sheep interleukin 2, sheep interferon gamma and sheep interferon tau and preparation method of fused protein
InactiveCN107383204AExtended half-lifeHigh expressionBacteriaMicroorganism based processesAnti virusAnimal science
The invention discloses a fusion protein composed of goat interleukin 2, goat interferon gamma and goat interferon tau and a preparation method thereof. The fusion protein is composed of goat interleukin 2, goat interferon gamma and goat interferon τ is formed by connecting with a flexible linker, the fusion protein is mixed with a freeze-drying protective agent, and then freeze-dried to obtain recombinant sheep peginterferon. The recombinant sheep long-acting interferon can significantly increase the half-life of sheep interferon, which is more than 15 times higher than that of ordinary sheep interferon, has broad-spectrum antiviral effect and can improve the immune response of sheep itself.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Recombinant goat long-acting interferon gamma, fusion protein for preparing long-acting interferon gamma and preparation method thereof
InactiveCN108840941AExtended half-lifeLow costBacteriaAntibody mimetics/scaffoldsHalf-lifeInterleukin II
The invention discloses a recombinant goat long-acting interferon gamma, a fusion protein for preparing the long-acting interferon gamma and a preparation method thereof. The fusion protein is formedby connecting goat interleukin 2 and a goat interferon through a flexible linker. The fusion protein and a freezing and drying protecting agent are blended and frozen and dried to obtain the recombinant goat long-acting interferon gamma. The recombinant goat long-acting interferon gamma can improve the half-life period of the goat interferon remarkably. Compared with the half-life period of a common goat interferon gamma, the half-life period of the recombinant goat long-acting interferon gamma is improved by over 10 times. The recombinant goat long-acting interferon gamma also has broad spectrum antiviral action and can improve immune response of the goat.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Fusion protein prepared from goat albumin, goat interferon gamma and goat interleukin Tau and preparation method thereof
The invention discloses fusion protein prepared from goat albumin, goat interferon gamma and goat interleukin Tao and a preparation method thereof. The fusion protein is formed by goat albumin, goat interferon gamma and goat interleukin Tau through the connection by flexible linkers. A recombinant goat pegylated interferon can be obtained through freeze drying after the mixing of the fusion protein and freeze drying protection agents. The recombinant goat pegylated interferon can obviously prolong the goat interferon half life; the half life is prolonged by 17 times or more through being compared with that of ordinary goat interferon; the broad-spectrum antiviral effects are achieved; the immune response of the goat per se can be improved.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
Recombinant bovine long-term interferon and fusion protein for preparing same and preparation method of recombinant bovine long-term interferon
InactiveCN107253997AExtended half-lifeHigh expressionBacteriaMicroorganism based processesHalf-lifeInterleukin II
The invention discloses a recombinant bovine peginterferon, a fusion protein for preparing the peginterferon and a preparation method thereof. The fusion protein is formed by connecting bovine interleukin 2 and bovine interferon α through a flexible linker. The fusion protein and After the lyoprotectant is mixed, Hu Jing freeze-dries to obtain the recombinant bovine peginterferon. The recombinant bovine long-acting interferon can significantly increase the half-life of bovine interferon, which is more than 10 times higher than that of common bovine interferon, has broad-spectrum antiviral effect and can improve the immune response of bovine itself.
Owner:WUHU YINGTE FEIER BIOLOGICAL PROD IND RES INST CO LTD
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