Topical regional neuro-affective therapy with caryophyllene

Abstract

A method of treating a disease state or condition in humans via topical brainstem afferent stimulation therapy via the administration of caryophyllene to the back of the neck of a human patient to provide regional neuro-affective therapy is disclosed. In certain embodiments, the drugs are incorporated into a pharmaceutically acceptable topical carrier, e.g., a cream, gel, lotion or foam.

Description

FIELD OF THE INVENTION[0001]The invention relates to topical regional neuro-affective therapy (“TRNA THERAPY”) with a caryophyllene(s). This is accomplished via administration of effective amounts of these agents on the back of the neck.BACKGROUND OF THE INVENTION[0002]The approximate 2½ pound human brain is comprised of the most complex material known to man. The neuron, the primary functional cell of the nervous system, operates on the basis of electrical impulses that result in the release of neurochemical substances (neurotransmitters) at specific receptors: dopamine, serotonin, acetylcholine, norepinephrine, gamma-amino butyric acid (GABA), and many others. There are estimated to be 80-100 billion (10 times the world population) neurons in the average human brain. These neurons, in turn, make 200-300 billion coded connections with other neurons to accomplish the complex tasks of the human body.[0003]The brainstem serves as the vital pathway for relay and processing of neural im...

AI Technical Summary

Benefits of technology

This patent describes a method of administering a drug called caryophyllene to treat medical conditions. The drug can be injected or implanted at the back of the neck and released over time. The implantable formulation can include solid or liquid drugs, such as microspheres or microcapsules, that provide a controlled or sustained release of the drug at the site of administration. This method allows for targeted treatment and reduced systemic side effects.

Problems solved by technology

While benefits for treating symptoms of diverse neurologic and psychiatric conditions have been known and practiced by ancient civilizations for thousands of years, marijuana's psychoactive effects have also led to abuse and labeling as a “gateway drug” for more addictive compounds.

However, increasing number of states have challenged this position and legalized cannabis within their territories with varying restrictions and conditions for use.