Topical arginine-silicate-inositol for wound healing
a technology of arginine-silicate inositol and wound healing, which is applied in the field oftopical or transdermal delivery, can solve the problems of limited success of wound closure methods, inability to resist and more dangerous infections, and inability to cure infections, etc., and achieves the effects of promoting hair growth, hair growth, and hair growth
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Benefits of technology
Problems solved by technology
Method used
Image
Examples
example 1
[0077]Animals: In this study, 42 male, 4 months old, Wistar albino rats weighing between 250 and 300 g were used. Animals were housed at 21° C. with a day / night cycle of 12 h. During the study these animals were fed ad libitum standard rodent feed. Guidelines for the care and use of animals approved by the relevant institution were followed and the local ethics committee approved this study.
[0078]Anesthesia: The rats were anaesthetized with single intramuscular injection of 6 mg / kg xylazine hydrochloride (Rompun, Bayer, 23.32 mg / ml) and 85 mg / kg ketamine hydrochlorure (Ketalar, Parke-Davis, 50 mg / ml).
[0079]Test drugs: 4% and 10% arginine-silicate inositol (ASI)(w / w) ointment, and cold cream (Botafarma, 12.5% spermaceti+12% white wax+56% liquid paraffin+0.5% borate of soda+19% distilled water) were used in this study.
[0080]Wound model: The dorsal surfaces of the rats were shaved and prepared with 10% antiseptic povidone-iodine solution (Kim-Pa, Poviiodeks, % 10 povidone-iodine). Then...
example 2
[0107]Wound model: The dorsal surfaces of the rats will be shaved and prepared with 10% antiseptic povidone-iodine solution (Kim-Pa, Poviiodeks, % 10 povidone-iodine). Then a surgical cautery will be used to create a full-thickness burn wound.
[0108]Measurements: On every bandage change, the wound boundaries will be traced on a transparent sheet with a fine-tipped permanent marker. These transparent sheets will be scanned and the areas of wound sites and epithelization fronts will be measured with the help of the paint-brush (PB) computer program. The data obtained will be calculated with the following formula: Area (cm2)=P / K.M, where P is the value of a particular wound site obtained on the PB, K is a rate constant for expressing the values of the PB as cm2, and M is the magnitude of tracings after scanning. During the qualitative examination, the expansion rate, the day wound contraction started, the fraction of the wound healed with contraction, the rate of wound contraction, the ...
example 3
[0109]Wound model: The dorsal surfaces of the rats will be shaved and prepared with 10% antiseptic povidone-iodine solution (Kim-Pa, Poviiodeks, % 10 povidone-iodine). Then the rats will be given a 5 cm by 5 cm abrasion wound.
[0110]Measurements: On every bandage change, the wound boundaries will be traced on a transparent sheet with a fine-tipped permanent marker. These transparent sheets will be scanned and the areas of wound sites and epithelization fronts will be measured with the help of the paint-brush (PB) computer program. The data obtained will be calculated with the following formula: Area (cm2)=P / K.M, where P is the value of a particular wound site obtained on the PB, K is a rate constant for expressing the values of the PB as cm2, and M is the magnitude of tracings after scanning. During the qualitative examination, the expansion rate, the day wound contraction started, the fraction of the wound healed with contraction, the rate of wound contraction, the day epithelizatio...
PUM
Property | Measurement | Unit |
---|---|---|
diameter | aaaaa | aaaaa |
w/w | aaaaa | aaaaa |
wound healing time | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com