Fluid therapy method

Abstract

A fluid therapy method for an ADHF patient includes setting a urine output rate desired threshold, setting one or more desired negative net gain rates, and optionally setting a total fluid loss goal. The urine output of the patient is monitored and fluid is automatically administered to the patient at increasing rates to equal to or approximately match the patient's increasing urine output rates until the patient's urine output rate reaches the set urine output rate desired threshold. Thereafter, fluid is administered to the patient at rates to achieve the set desired negative net gain rate until the fluid loss goal is reached. Thereafter, until the end of therapy, fluid is administered to the patient at rates equal to or approximately equal to the monitored urine output rates.

Description

RELATED APPLICATIONS[0001]This application claims benefit of and priority to U.S. Provisional Application Ser. No. 61 / 954,089 filed Mar. 17, 2014 under 35 U.S.C. §§119, 120, 363, 365, and 37 C.F.R. §1.55 and §1.78 and is incorporated herein by this reference.FIELD OF THE INVENTION[0002]This invention relates to a patient hydration system and method wherein the rate of hydration fluid delivered to the patient is automatically adjusted based on the urine output and clinician settings in order to reach a clinician desired net fluid loss by the patient.BACKGROUND OF THE INVENTION[0003]Acute decompensated heart failure (ADHF) is the largest cause of hospitalization in the United States among patients 65 and older. See Lloyd-Jones D, Adams R, Carnethon M, et al. Heart disease and stroke statistics—2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2009; 119(3):e21-e181 incorporated herein by this reference. These ...

AI Technical Summary

Benefits of technology

This patent describes a fluid management system and a method for controlling a patient's fluid loss. The system makes it easier for nurses to manage patients with excess fluid and helps to maintain a high urine rate. The method can treat patients with excess fluid and also provide fluid therapy.

Problems solved by technology

These patients often enter the emergency room with significant volumes of excess fluid and a number of complications due to this excess fluid.

There are a number of factors that contribute to the poor prognosis of these patients.

Patients with ADHF often have a number of co-morbidities, complicating their treatment and giving them a poor prognosis.

This also contributes to the fact that patient response to diuretics is unpredictable.

A paradox of the ADHF patient involves the fact that while these patients may have 40 additional liters of fluid in their body, they may be intravascularly dehydrated.

The injection of diuretics then only causes fluid to be lost from the already depleted intravasculature.

Once the patient fails to respond to diuretics, treatment becomes very difficult.

One of the ways ADHF kills patients is by retaining so much fluid that the fluid begins to build up in the patient's lungs, eventually causing pulmonary edema and eventually causing the lungs to fail.

If diuretics fail to induce urine output due to diuretic resistance, the clinician loses an effective tool for protecting the patient from pulmonary edema.

The intravascular depletion caused by diuretic therapy can also reduce blood supply to the kidney, causing additional damage to the kidney.

While a number of studies have demonstrated that Ultrafiltration can effectively remove fluid from ADHF patients, one of the largest studies of the therapy to date has found that Ultrafiltration may lead to more kidney damage than diuretic therapy.

CHF patients retain salt and water to maintain blood pressure and their salt intake is severely limited by the traditional therapy paradigm.

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