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Dietary composition and method for promoting healthy hair growth and melanogenesis

a technology of dietary composition and hair growth, applied in the field of dietary composition and method of combating graying of mammalian hair, can solve the problems of hair loss, aging, ill health, and hair graying, and achieve the effects of preventing retarding, and/or reversing hair graying, and preventing hair graying

Inactive Publication Date: 2011-11-24
BEGGAN CATHY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0014]It is another object of the invention to provide a dietary composition that promotes healthy hair in humans comprising catalase and a synergistic core component comprising copper, vitamin B6, biotin, para-aminobenzoic acid, folic acid, zinc, and pantothenic acid.
[0027]It is yet another object of the invention to provide a method of retarding, preventing, and / or reversing the graying of hair by orally administering a dietary composition comprising L-tyrosine, an antioxidant component, 5α-reductase inhibitors, catalase, and a synergistic core component comprising copper, vitamin B6, biotin, para-aminobenzoic acid, folic acid, zinc, and pantothenic acid.

Problems solved by technology

With age, hair tends to lose its volume, sheen and color, resulting in gray hair having thin and brittle appearance.
This transformation is often regarded as a sign of old age, ill health, and bodily decline.
Unfortunately, there are currently very limited options available.
However, applying coloring and / or bleaching has its disadvantages.
One such disadvantage is the nuisance of regular touch up of colored / bleached hair.
Furthermore, coloring / bleaching could be messy and its outcomes could be at times unpredictable, especially when it is self-applied.
Additionally, coloring / bleaching could pose health risks to users.
For example, irritating chemicals used in coloring / bleaching compositions cause allergic reactions and eye irritation in some cases.
Moreover, certain ingredients in coloring / bleaching compositions may penetrate human and animal skin and cause health risks.
These ingredients have been reported to cause cancer in at least one animal species in lifetime feeding studies.
However, these findings remain inconsistent, and thus, potential health risks posed by coloring / bleaching are unknown.
However, these ingredients may not achieve their effects on gray hair to their fullest potential, as the ingredients are unaccompanied by suitable agents to amplify the beneficial effects on hair.
H2O2 is a byproduct of oxygen metabolism and a major contributor to oxidative damage due to its strong oxidizing capacity.
However, when excess H2O2 accumulates, cells and their components incur oxidative damage.
The damage could irreversibly deactivate the function of tyrosinase.
Furthermore, accumulation of H2O2 ultimately leads to apoptosis (“cell death”) of hair follicle melanocytes, cells that perform melanogenesis.
As a result of these events, melanogenesis is hindered, leading to gradual loss of hair color.
As the body produces less catalase with age, imbalance occurs in the relative concentrations of catalase and H2O2.
Intravenous injection or topical application of catalase is undesirable, as these methods could be inconvenient, ineffective, and / or unsafe.
However, the effect of orally administered catalase without proper enhancing agents is inadequate to prevent graying of hair.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0073]

IngredientsAmount per dayCatalase5,000 IUCopper (oxide)1 mgVitamin B6 (pyridoxine hydrochloride)10 mgBiotin300 mcgPABA (para amino benzoic acid)200 mgFolic Acid400 mcgZinc (oxide)10 mgPantothenic Acid (calcium pantothenate)300 mgHorsetail (7% extract)100 mgSaw Palmetto (40-45% extract)300 mgPlant Sterols (45% beta-sitosterol)100 mgFo Ti (powder)10 mgNettle Root Extract100 mgChlorophyll10 mgBarley Grass10 mgL-Tyrosine200 mg

example 2

[0074]

IngredientsAmount Range per DayCatalase 2,500 IU - 10,000 IUCopper (oxide)1 mg - 3 mgVitamin B6 (pyridoxine hydrochloride) 5 mg - 20 mgBiotin200 mcg - 600 mcgPABA (para amino benzoic acid)100 mg - 400 mgFolic Acid200 mcg - 600 mcgZinc (oxide) 5 mg - 20 mgPantothenic Acid (calcium pantothenate) 50 mg - 400 mgHorsetail (7% extract) 50 mg - 300 mgSaw Palmetto (40-45% extract)100 mg - 600 mgPlant Sterols (45% beta-sitosterol) 50 mg - 300 mgFo Ti (powder) 5 mg - 20 mgNettle Root Extract 50 mg - 250 mgChlorophyll 5 mg - 20 mgBarley Grass 5 mg - 30 mgL-Tyrosine100 mg - 300 mg

[0075]The dietary compositions as shown in Examples 1 and 2 can be prepared into various forms including, but not limited to liquid, bar, powder, gel, gelatin capsule, capsule, tablet, or the like. Preferably, the dietary composition as shown in Examples 1 or 2 is provided in the form of a capsule comprising gelatin, magnesium stearate, and silicon dioxide. Other acceptable carriers and / or excipients known in the...

example 3

Demonstration of Pigment Restorative Effect of the Dietary Composition According to Example 1

[0078]A number of test subjects have taken the dietary composition as described in Example 1 for varying lengths of time. Summarized below are reported results based on the subjects' qualitative observation.

[0079]Subject No. 1—A 53 year old female took the dietary composition according to Example 1 in two portions daily for six weeks. At the beginning of the trial, the subject's hair was brown with enough gray hair to impart the “salt and pepper” effect. After three weeks, the subject noticed increase in her daily energy level as well as volume in her hair. By the sixth week, the subject stopped coloring her hair, as gray hair was no longer visible.

[0080]Subject No. 2—A 47 year old male took the dietary composition according to Example 1 in two portions daily for five weeks. Prior to the trial, the subject had patches of gray hair on both sides of his head. By the fifth week, the gray hair h...

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PUM

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Abstract

A dietary composition for promoting melanogenesis in hair of a user comprising approximately 5,000 IU per day of catalase, a synergistic core component, 5-α-reductase inhibitors, an antioxidant component, and approximately 200 mg per day of L-tyrosine. Preferably, the synergistic core component comprises copper, vitamin B6, biotin, para-aminobenzoic acid, folic acid, zinc, and pantothenic acid. Further, 5-α-reductase inhibitors preferably comprise Saw palmetto, phytosterols, and nettle root extract. The antioxidant component preferably comprises horsetail, Fo-Ti, chlorophyll, and barley grass.

Description

FIELD OF INVENTION[0001]The present invention relates generally to a dietary composition and method of combating graying of mammalian hair. In particular, the dietary composition according to the present invention comprises a combination of catalase, a synergistic core component, 5α-reductase inhibitors, an antioxidant component, and L-tyrosine for retarding, preventing, and / or reversing the graying of hair of a user.BACKGROUND, OF THE INVENTION[0002]Hair is a keratin-containing filament that grows from the dermis of the skin. Found exclusively in mammals, hair often refers to two distinct structures: (1) the hair follicle; and (2) the shaft. The hair follicle is an organ located in the dermis of the skin. The main function of the hair follicle is to maintain stem cells to produce hair shaft. On the other hand, the hair shaft is always external to the skin. Roughly three components constitute the hair shaft. The first component, the cuticle, is the outermost structure comprising fla...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61K9/00A61P17/14A61K38/44
CPCA23L1/034A23L1/3002A23L1/302A23L1/304A23V2002/00A61K31/4188A61K31/4415C12Y111/01006A61K45/06A61K33/34A61K38/44A61K2300/00A23V2200/318A23V2250/0652A23V2250/1588A23V2250/1642A23V2250/2136A23V2250/705A23V2250/7052A23V2250/7056A23V2250/72A23L29/06A23L33/105A23L33/15A23L33/16A61P17/14
Inventor BEGGAN, CATHY
Owner BEGGAN CATHY
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