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Systems and methods for photoacoustic opthalmoscopy

a technology of opthalmoscopy and photoacoustic imaging, applied in the field of multimodal medical imaging, can solve the problems of unavoidable side effects of diabetic retinopathy treatment, decreased peripheral and night vision, and loss of vision, and reduce the oxygen to the retina

Inactive Publication Date: 2010-09-30
UNIV OF SOUTHERN CALIFORNIA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently, clinical treatment for late stage diabetic retinopathy is associated with unavoidable side effects that include diminished peripheral and night vision as well as loss of vision.
As diabetic retinopathy progresses the blood vessels supplying oxygen to the eye become blocked, which leads to decreased oxygen to the retina.

Method used

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  • Systems and methods for photoacoustic opthalmoscopy
  • Systems and methods for photoacoustic opthalmoscopy
  • Systems and methods for photoacoustic opthalmoscopy

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Embodiment Construction

[0021]Before any embodiments of the invention are explained in detail, it is to be understood that the invention is not limited in its application to the details of construction and the arrangement of components set forth in the following description or illustrated in the following drawings. The invention is capable of other embodiments and of being practiced or of being carried out in various ways. Also, it is to be understood that the phraseology and terminology used herein is for the purpose of description and should not be regarded as limited. The use of “including,”“comprising” or “having” and variations thereof herein is meant to encompass the items listed thereafter and equivalents thereof as well as additional items. The terms “mounted,”“connected” and “coupled” are used broadly and encompass both direct and indirect mounting, connecting and coupling. Further, “connected” and “coupled” are not restricted to physical or mechanical connections or couplings, and can include ele...

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Abstract

Various embodiments of the present invention include systems and methods for multimodal functional imaging based upon photoacoustic and laser optical scanning microscopy. In particular, at least one embodiment of the present invention utilizes a contact lens in combination with an ultrasound transducer for purposes of acquiring photoacoustic microscopy data. Traditionally divergent imaging modalities such as confocal scanning laser opthalmoscopy and photoacoustic microscopy are combined within a single laser system. Functional imaging of biological samples can be utilized for various medical and biological purposes.

Description

CROSS-REFERENCE TO RELATED APPLICATIONS[0001]This application claims priority benefit of U.S. Provisional Application No. 61 / 160,907, filed Mar. 17, 2009, and to U.S. Provisional Application No. 61 / 335,684, filed Jan. 11, 2010, each of which is incorporated herein by reference in their entirety.FIELD OF THE INVENTION[0002]Various embodiments of the present invention relate to multimodal medical imaging. In particular, various embodiments of the present invention relate to photoacoustic and laser scanning microscopy.BACKGROUND OF THE INVENTION[0003]Visual loss is often considered the most feared complication of human disease, other than death. Among all the causes that lead to irreversible vision loss, diabetic retinopathy remains a leading cause. Diabetic retinopathy is a vascular disorder that occurs as a complication of diabetes mellitus. It is estimated that more than 10 million adults over the age of 40 in the U.S. have diabetes mellitus. Early detection and treatment of diabete...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61B3/13H04R1/00G01J3/45G01J1/42A61B3/10
CPCA61B5/0059A61B5/0066A61B5/0095A61B8/10G01B9/02091G01N29/0681G01N29/2418G01B9/0203G01B9/02044A61B8/4472
Inventor ZHANG, HAO F.JIAO, SHULIANG
Owner UNIV OF SOUTHERN CALIFORNIA
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