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Fluid pressure actuated blood pumping systems and methods with continuous inflow and pulsatile outflow conditions

a technology of fluid processing system and pumping system, which is applied in the direction of positive displacement liquid engine, machine/engine, prosthesis, etc., can solve the problems of complex and sophisticated operation and performance demands of fluid processing system, size of conventional centrifuge, and inability to facilitate easy transportation between collection sites. , to achieve the effect of straightforward and accurate control functions

Inactive Publication Date: 2005-10-20
FENWAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

[0008] The invention provides systems and methods for processing blood and blood constituents that lend themselves to portable, flexible processing platforms equipped with straightforward and accurate control functions.

Problems solved by technology

Conventional blood centrifuges are of a size that does not permit easy transport between collection sites.
Furthermore, loading and unloading operations can sometimes be time consuming and tedious.
The operational and performance demands upon such fluid processing systems become more complex and sophisticated, even as the demand for smaller and more portable systems intensifies.

Method used

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  • Fluid pressure actuated blood pumping systems and methods with continuous inflow and pulsatile outflow conditions
  • Fluid pressure actuated blood pumping systems and methods with continuous inflow and pulsatile outflow conditions
  • Fluid pressure actuated blood pumping systems and methods with continuous inflow and pulsatile outflow conditions

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[0579] Whole blood was separated during various experiments into red blood cells and plasma in processing chambers 18 like that shown in FIG. 28. In one chamber (which will be called Chamber 1), whole blood circumferentially flowed in the channel 126 in the same direction as the chamber 18 was rotated (i.e., the chamber 18 was rotated in a counterclockwise direction). In the other chamber 18 (which will be called Chamber 2), whole blood circumferentially flowed in the channel 126 in a direction opposite to chamber rotation (i.e., the chamber 18 was rotated in a clockwise direction).

[0580] The average hematocrit for red blood cells collected were measured for various blood volume samples, processed at different combinations of whole blood inlet flow rates and plasma outlet flow rates. The following Tables summarize the results for the various experiments.

TABLE 1(Flow in the Same Direction as Rotation)Number of BloodAverage WholeAverage Hematocrit of RedSamples ProcessedBlood Hemat...

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Abstract

Blood processing systems and related methods place first and second fluid pressure actuated pump stations in in-line communication between a source and a destination. The systems and methods apply fluid pressure pump strokes to the first and second pump stations to convey fluid from the source to the destination. The systems and methods switch between a first flow mode and a second flow mode. In the first flow mode, the pump strokes draw a fluid volume into the first pump station from the source and expel a fluid volume from the second pump station to the destination. In the second flow mode, the pump strokes draw a fluid volume into the second pump station from the source and expel a fluid volume from the first pump station to the destination. The systems and methods synchronize the pump strokes so that fluid flow from the source is essentially continuous while fluid flow to the destination is pulsatile.

Description

RELATED APPLICATIONS [0001] This application claims the benefit of copending application Ser. No. 09 / 390,265 filed 3 Sep. 1999 and entitled “Fluid Pressure Actuated Blood Pumping Systems and Methods with Continuous Inflow and Pulsatile Outflow Conditions”. This application also claims the benefit of copending patent application Ser. No. 09 / 390,268 filed 3 Sep. 1999 and entitled “Programmable Fluid Pressure Actuated Blood Processing Systems and Methods”.FIELD OF THE INVENTION [0002] This invention relates to systems and methods for processing and collecting blood, blood constituents, or other suspensions of cellular material. BACKGROUND OF THE INVENTION [0003] Today people routinely separate whole blood, usually by centrifugation, into its various therapeutic components, such as red blood cells, platelets, and plasma. [0004] Conventional blood processing methods use durable centrifuge equipment in association with single use, sterile processing systems, typically made of plastic. The...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61M1/02A61M1/10A61M1/30A61M1/36A61M37/00F04B13/02F04B43/02F04B49/06
CPCA61M1/1037A61M1/30A61M1/3633A61M2205/128A61M2205/331A61M2205/3393A61M1/3696F04B43/026F04B49/065F04B2205/09A61M1/302A61M1/303A61M1/308F04B13/02A61M2205/3334A61M60/113A61M60/43A61M60/892A61M60/894A61M60/546A61M60/427A61M60/109A61M60/36A61M60/847A61M1/362262A61M1/362265A61M1/362261A61M1/36222A61M1/362266
Inventor WESTBERG, TOMVISHNOI, ROHITVANDLIK, MARK R.
Owner FENWAL
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