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Medicinal composition for treating fatty liver, its preparation and use

A composition and fatty liver technology, which can be applied in the directions of drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of aggravating liver fat deposition and the like

Active Publication Date: 2007-01-17
CHINA RESOURCES SANJIU MEDICAL & PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no specific drug for the treatment of fatty liver in modern medicine. Some blood lipid-lowering drugs in conventional treatment can promote the transport of lipids in the blood to the liver for metabolism, but aggravate the fat deposition in the liver.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Weigh 50 grams of Radix Polygoni Multiflori, 300 grams of Danshen, 50 grams of Alisma, 250 grams of lotus leaves, 50 grams of cassia seeds, 300 grams of vinegar Bupleurum and 50 grams of turmeric, and reflux extraction with 4 times the amount of 20% ethanol, extracting 4 times, 1 hour each time; extract and concentrate and dry under reduced pressure to obtain 210 grams of dry paste; add 100 grams of lactose, 50 grams of starch, 40 grams of microcrystalline cellulose and 30 grams of sodium carboxymethyl starch and mix well. with 5% PVPK 30 Solution-made soft material, granulated with a 16-mesh sieve, dried at 60°C and granulated. Add 4 grams of magnesium stearate to the granulated granule, mix uniformly, and compress to become the pharmaceutical composition tablet of the present invention.

Embodiment 2

[0030] Weigh 250 grams of Zhishouwu, 50 grams of Danshen, 300 grams of Alisma, 30 grams of lotus leaves, 300 grams of cassia seeds, 50 grams of vinegar Bupleurum and 300 grams of turmeric, and use 12 times the amount of 90% ethanol to reflux for 4 hours to extract 1 times; extract and concentrate and dry under reduced pressure to obtain 250 grams of dry paste; add 20 grams of starch, 60 grams of microcrystalline cellulose, and 60 grams of talcum powder, mix well, and pack into No. 1 capsules.

Embodiment 3

[0032] Weigh 150 grams of Radix Polygoni Multiflori, 120 grams of Salvia Miltiorrhiza, 150 grams of Alisma, 80 grams of lotus leaves, 200 grams of cassia seeds, 100 grams of vinegar Bupleurum and 120 grams of turmeric, reflux extraction with 5 times the amount of 60% ethanol, and extract 3 times, 2 hours each time; extract and concentrate and dry under reduced pressure to obtain 190 grams of dry paste; add 250 grams of dextrin and 3 grams of protein sugar, use 75% ethanol to make soft materials, make granules, dry at 60 ° C, pass through a 14-mesh sieve for granulation , to obtain the pharmaceutical composition granules of the present invention.

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PUM

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Abstract

An orally taken Chinese medicine for treating fatty liver is prepared from 7 Chinese-medicinal materials including fleece flower root, red sage root, alismatis rhizome, lotus leaf, etc. Its preparing process is also disclosed.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and relates to a formula of a pharmaceutical composition for treating fatty liver, a preparation method and application thereof. Background technique [0002] Fatty liver is a clinicopathological syndrome characterized by fatty degeneration and fat storage in hepatic parenchymal cells. Fatty liver is mainly related to obesity, diabetes and dyslipidemia, and the incidence rate has a clear upward trend. At present, there is no specific drug for the treatment of fatty liver in modern medicine. Some blood lipid-lowering drugs in conventional treatment can promote the transport of lipids in the blood to the liver for metabolism, but instead aggravate the fat deposition in the liver. Traditional Chinese medicine has a clear curative effect on the prevention and treatment of fatty liver, and has less toxic and side effects. It is a research hotspot in the field of fatty liver preve...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P1/16
Inventor 张伯礼高秀梅朱晓薇李玉红王巍郭俊华刘虹
Owner CHINA RESOURCES SANJIU MEDICAL & PHARMA
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