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Compound breviscapine pills

A technology of breviscapine and dropping pills, which is applied in the directions of pill delivery, pharmaceutical formulations, active ingredients of hydroxyl compounds, etc., can solve the problems of low bioavailability, unsatisfactory curative effect, slow absorption of breviscapine, etc.

Inactive Publication Date: 2006-05-10
胡秀爱
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it also has its drawbacks. The active ingredient breviscapine still has problems such as relatively slow absorption by the human body, low bioavailability, and slow onset of action. Efficacy is still unsatisfactory

Method used

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  • Compound breviscapine pills

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Prescription: Breviscapine 20g

[0021] Musk 10g

[0022] ice flakes 100g

[0023] Macrogol 4000 80g

[0024] Made into 5000 capsules

[0025] Preparation method: Take the prescribed amount of polyethylene glycol 4000 and melt it; take an appropriate amount of absolute ethanol, add scutellarin, musk, and borneol, stir to dissolve; mix the liquid medicine with the melted polyethylene glycol 4000, and continue stirring , evaporate the ethanol, place it in a preheated dropping pill machine, keep it warm at 90°C, and use methyl silicone oil as a coolant to drop it into pills. Example 2, example 3 are made with the same method. Twice a day, take 2-4 capsules each time, or take it in emergency.

Embodiment 4

[0027] Prescription: Breviscapine 20g

[0028] Musk 16

[0029] ice flakes 60g

[0030] Sodium stearate 80g

[0031] Made into 5000 capsules

[0032] Preparation method: take the prescribed amount of sodium stearate and melt it; take an appropriate amount of absolute ethanol, add breviscapine, musk, and borneol, and stir to dissolve; mix the liquid medicine with the molten sodium stearate, continue to stir, and evaporate Remove ethanol, put it in a preheated dropping pill machine, keep it warm at 88°C, use methyl silicone oil as a coolant to drip into pills, and you get it. Example 5 and Example 6 were prepared with the same method. Twice a day, take 2-4 capsules each time, or take it in emergency.

Embodiment 7

[0034] Prescription: Breviscapine 20g

[0035] Musk 24g

[0036] ice flakes 30g

[0037] Macrogol 4000 50g

[0038] Poloxamer 20g

[0039] Made into 5000 capsules

[0040] Preparation method: Take the prescribed amount of polyethylene glycol 4000 and poloxamer, melt; take an appropriate amount of absolute ethanol, add scutellarin, musk, borneol, stir to dissolve; mix the liquid medicine with the melted polyethylene glycol 4000 and poloxamer Mix the loxamer evenly, keep stirring, shake off the ethanol, place it in a preheated dropping pill machine, keep it warm at 85°C, use methyl silicone oil as a coolant to drip into pills, and get it. Twice a day, take 2-4 capsules each time, or take it in emergency.

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PUM

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Abstract

The invention discloses a compound Chinese medicinal drop pill containing active constituent of Breviscapine, which comprises the following constituents (by weight percentage): Breviscapine active component 1 part, musk 0.5-3 parts, borneol 0.5-5 parts, and pharmaceutically acceptable medicinal carrier or adjuvant.

Description

technical field [0001] The invention relates to a compound traditional Chinese medicinal preparation for treating cardiovascular and cerebrovascular diseases, in particular to a compound breviscapine dripping pill. Background technique [0002] Cardiovascular and cerebrovascular diseases are common and frequently-occurring diseases, and are the number one killer of human beings. Among them, cardiovascular disease takes the lives of 12 million people every year, which is close to 1 / 4 of the total death of the world's population, and has become the number one enemy of human health. Although the mortality rate of cardiovascular disease has declined to varying degrees in most countries except Eastern European countries in the past 30 years, it is still the first cause of death in men over 45 years old in most countries, and the second only to cancer in women. The two causes of death have seriously affected the life expectancy and quality of life of human beings. Therefore, dru...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/20A61K31/045A61K31/7048A61K35/55A61P9/00
Inventor 胡秀爱程高楼
Owner 胡秀爱
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