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Medicine composition with synergetic function

A technology of composition and medicine, applied in the field of medicinal combination containing natural plant extracts or monomers, to achieve the effect of good therapeutic effect

Inactive Publication Date: 2006-03-08
詹宇亮
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As for whether the two can be used in combination for other diseases (such as cardiovascular disease, Alzheimer's disease, etc.), the prior art does not even have similar hints.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0257] Example 1 tablet

[0258] Take 2000g of Salvia miltiorrhiza, add 95% ethanol to reflux for 1.5 hours, filter, recover the ethanol from the filtrate to a thick ointment; add water to decoct the dregs of the medicine for 1 hour, filter, combine the filtrate with the above thick ointment, concentrate under reduced pressure to an appropriate amount, add an appropriate amount of auxiliary materials, Mix well. Take 1000g of Radix Paeoniae Rubra, crush it into a coarse powder, add 75% ethanol to reflux and extract three times, the first and second times each for 2 hours, and the third time for 1 hour, combine the extracts, concentrate under reduced pressure to about 400ml, and extract three times with n-butanol , 300ml each time, combine the n-butanol extract, concentrate under reduced pressure until there is no n-butanol smell, add 200ml of water, heat to dissolve, filter, spray-dry the filtrate, mix evenly with the above-mentioned Danshen extract, and routinely press into ta...

Embodiment 2

[0259] Example 2 Capsules

[0260] Take 5000g of Salvia miltiorrhiza, add 90% ethanol to reflux for 1.5 hours, filter the extract, recover ethanol from the filtrate and concentrate to an appropriate amount, and set aside; add 50% ethanol to the medicinal residues and heat to reflux for 1.5 hours, filter the extract, recover ethanol from the filtrate and concentrate to an appropriate amount ,spare. Another 5 g of paeoniflorin was uniformly mixed with the above-mentioned salvia miltiorrhiza extract, then starch and magnesium stearate were added, mixed evenly, packed into hard capsules, and compressed into 1000 soft capsules. After testing, each capsule contains salvia miltiorrhiza (in the form of salvianolic acid B (C 36 h 30 o 16 )) is 100mg, and paeoniflorin 5mg.

Embodiment 3

[0261] Embodiment 3 soft capsules

[0262] Take 2000g of Salvia miltiorrhiza, add 90% ethanol to reflux for 1.5 hours, filter the extract, recover ethanol from the filtrate and concentrate to an appropriate amount, and set aside; add 50% ethanol to the dregs and heat to reflux for 1.5 hours, filter the extract, recover ethanol from the filtrate and concentrate to an appropriate amount ,spare. Another 20 g of paeoniflorin was uniformly mixed with the above-mentioned salvia miltiorrhiza extract, then vegetable oil was added to mix evenly, gelatin was used as the capsule shell material, and 1000 soft capsules were compressed into. After testing, each capsule contains Danshen (Tanshinone II A (C 19 h 18 o 3 )) is 2mg, and paeoniflorin 20mg.

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PUM

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Abstract

The present invention relates to a medicine composition, preparation method and its application. The described medicine composition contains salvia root and peony root for preventing and curing diabetes and complicating diseases, senile dementia, angiocardiopathy, cerebrovascular diseases, hyperlipemia, fatty liver and thrombosis of central vein of retina.

Description

technical field [0001] The present invention relates to a pharmaceutical combination, in particular, a pharmaceutical combination containing natural plant extracts or monomers for the treatment and / or prevention of cardiovascular and cerebrovascular diseases, diabetes and its complications, senile dementia, retinal central Vein obstruction, hyperlipidemia, fatty liver, and for preventing recurrence of cardiovascular and cerebrovascular diseases. Background technique [0002] Diabetes is one of the diseases with high incidence in the world. According to WHO research report, there are more than 150 million diabetic patients worldwide. Diabetes is not only life-threatening due to acute complications, but more importantly, its various serious chronic complications such as: diabetic nephropathy (DN), diabetic retinopathy (DR), diabetic neuropathy, diabetic fatty liver and diabetes combined Hypertension and hyperlipidemia have high morbidity and disability / death rates, so they a...

Claims

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Application Information

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IPC IPC(8): A61K36/65A61P3/10A61P3/06A61P1/16A61P9/00
Inventor 詹宇亮毛成文
Owner 詹宇亮
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