Composite vegetable drug for treating type II diabetes and increasing insulin sensitivity, extracts and extraction method

A technology of insulin sensitization and herbal medicine, which is applied in the extraction of combined herbal medicine extracts, and the field of combined herbal medicine and its extracts for the treatment of type II diabetes and insulin sensitization, which can solve the problem that mechanism research has not been carried out and in-depth, lacking Insulin resistance and other problems, to achieve the effect of low cost, lower random blood sugar, and less side effects

Active Publication Date: 2006-02-22
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the current research is limited to the observation of improving IR, and the mechanism research has not been carried out and in-depth, especially the molecular biological mechanism of IR has not been involved. At present, there is still a lack of effective traditional Chinese medicine preparations for treating insulin resistance in clinical practice.

Method used

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  • Composite vegetable drug for treating type II diabetes and increasing insulin sensitivity, extracts and extraction method
  • Composite vegetable drug for treating type II diabetes and increasing insulin sensitivity, extracts and extraction method
  • Composite vegetable drug for treating type II diabetes and increasing insulin sensitivity, extracts and extraction method

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Embodiment 1

[0032] Embodiment 1. This embodiment is a combination herbal medicine for treating type II diabetes and insulin sensitization and its extract and its extraction method. The weight (gram) formula of the combined herbal medicine extract raw material is: Cortex Moutan 1710, Ze Xie 1026, Polygonum multiflorum 1026, Polygonatum 1539, Anemarrhena 1026, Coptis 342;

[0033](a) Add 60% ethanol with 7 times the amount of medicinal materials to Coptidis Rhizoma, heat and reflux extraction for 3 times, each time for 1.8 hours, combine the extracts, recover ethanol under reduced pressure, and concentrate to a clear paste with a relative density of 1.25 at 50°C to obtain Coptidis Rhizome extract Coptis chinensis ointment;

[0034] (b) Cortex Moutan adds 6% sodium chloride NaCl aqueous solution of 4 times of medicinal material amount, soaks after 6 hours, distills, collects the initial distillation liquid 3.5 times of medicinal material amount and preserves in another device; Continue disti...

Embodiment 2

[0036] Embodiment 2. The present embodiment is a combination herbal medicine for treating type II diabetes and insulin sensitization and its extract and its extraction method. The weight (gram) formula of the combined herbal medicine extract raw material is: Cortex Moutan 1710, Ze Xie 1026, Polygonum multiflorum 1026, Polygonatum 1539, Anemarrhena 1026, Coptis 342;

[0037] (a) Add 60% ethanol with 7 times the amount of medicinal materials to Coptidis Rhizoma, heat and reflux extraction for 3 times, each time for 1.8 hours, combine the extracts, recover ethanol under reduced pressure, and concentrate to a clear paste with a relative density of 1.25 at 50°C to obtain Coptidis Rhizome extract Coptis chinensis ointment;

[0038] (b) Cortex Moutan adds 6% sodium chloride NaCl aqueous solution of 4 times of medicinal material amount, soaks after 6 hours, distills, collects the initial distillation liquid 3.5 times of medicinal material amount and preserves in another device; Contin...

Embodiment 3

[0040] Embodiment 3, the present embodiment is a kind of combined herbal medicine for treating type II diabetes and insulin sensitization and its extract and its extraction method. Xie 1231, Polygonum multiflorum 821, Polygonatum 1847, Anemarrhena 821, Coptis 274;

[0041] (a) Add 70% ethanol that is 5 times the amount of medicinal materials to Coptidis Rhizoma, heat and reflux for extraction 4 times, each time for 1.5 hours, combine the extracts, recover ethanol under reduced pressure, and concentrate to a clear paste with a relative density of 1.05 at 50°C to obtain Coptidis Rhizome extract Coptis chinensis ointment;

[0042] (b) Cortex Moutan adds 7% sodium chloride NaCl aqueous solution of 3 times the amount of medicinal material, soaks for 4.5 hours, distills, collects 3 times the amount of medicinal material of the first distillate and saves it in another device; continue distilling until the distillate does not show milky white, and the medicinal The slag and residual ...

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Abstract

Disclosed is a composite vegetable drug for treating type II diabetes and increasing insulin sensitivity, extracts and extraction method, wherein the medicament is prepared from bark of peony root, oriental water plantain rhizome, fleece-flower root, Siberian solomonseal rhizome, anemarrhena rhizome, goldthread root through extracting by ethanol backflow, concentrating, wet distillation, stewing, collecting crystal and drying, mixing, drying and disintegrating into fines.

Description

technical field [0001] The present invention relates to combined herbal medicine and its extract, especially the combined herbal medicine and its extract for treating type II diabetes and insulin sensitivity; the invention also relates to the extraction method of the combined herbal medicine extract. Background technique [0002] Diabetes is a common clinical endocrine and metabolic disease. With the improvement of living standards and changes in lifestyle, the incidence of diabetes has increased year by year. In my country, the incidence has reached 3%, of which more than 90% are type 2 diabetes. Research on its prevention and treatment It is listed as one of the main tasks of the medical profession today. Both at home and abroad are constantly exploring new mechanisms of diabetes pathogenesis and new ways of treatment. Insulin resistance (Insulin resistance, IR) is a prominent feature of type 2 diabetes. Insulin resistance is an important factor in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61K9/00A61P3/10A61P5/50
Inventor 蔡宝昌潘扬章晨峰曹亮
Owner JIANGSU KANION PHARMA CO LTD
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