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Application of medicine contg. sealwort for preparing medicine of anti-aspirin-resistance

A technology of aspirin and medicine, which is applied in the application field of traditional Chinese medicine composition in the preparation of medicines for treating aspirin resistance, and can solve problems such as aspirin resistance

Inactive Publication Date: 2006-01-25
TIANJIN TASLY PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to alleviate the phenomenon of aspirin resistance that occurs when cardiovascular and cerebrovascular patients use aspirin drugs to treat cardiovascular and cerebrovascular diseases, some scientific researchers are currently looking for drugs that can replace or alleviate the phenomenon of aspirin resistance. Some drugs are tested in order to find new uses of their drugs to solve the phenomenon of aspirin resistance caused by current aspirin use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0070]Get 400g of Rhizoma Chuanxiong, 534g of Radix Polygoni Multiflori, 534g of Rhizoma Polygonatum (made), 400g of Safflower, 400g of Epimedium, 267g of Wulingzhi (made of vinegar), 400g of Salvia miltiorrhiza for later use;

[0071] The above seven flavors are decocted three times with water, the first time is 3 hours, the second and third times are 1 hour each, the decoction is combined, filtered, the filtrate is concentrated to a relative density of about 1.24, and ethanol is added to make the alcohol content reach 50%. ; filter the supernatant, recover ethanol, concentrate to a thick paste, dry, crush, sieve, add appropriate amount of auxiliary materials, mix well, make granules, dry and press into 1000 tablets, coat with sugar, and get ready.

Embodiment 2

[0073] Take 600g of Rhizoma Chuanxiong, 250g of Radix Polygoni Multiflori, 750g of Rhizoma Polygonatum (made), 200g of Safflower, 200g of Epimedium, 450g of Wulingzhi (made of vinegar), 200g of Salvia miltiorrhiza for later use;

[0074] The above seven flavors are decocted three times with water, the first time is 4 hours, the second and third time are 1.5 hours each, the decoction is combined, filtered, the filtrate is concentrated to a relative density of about 1.05-1.30, and ethanol is added to make the alcohol content reach 60%. Stand still; filter the supernatant, recover ethanol, concentrate to a thick paste, dry, pulverize, sieve, add appropriate amount of auxiliary materials, mix well, make granules, and obtain.

Embodiment 3

[0076] Take 200g of Rhizoma Chuanxiong, 750g of Polygonum multiflorum, 250g of Rhizoma Polygonatum (made), 600g of Safflower, 600g of Epimedium, 100g of Wulingzhi (made of vinegar), 600g of Salvia miltiorrhiza for later use;

[0077] The above seven flavors are decocted three times with water, the first time is 3.5 hours, the second and third time are 2 hours each, the decoctions are combined, filtered, the filtrate is concentrated to a relative density of about 1.20-1.30, and ethanol is added to make the alcohol content reach 70%. Stand still; filter the supernatant, recover ethanol, concentrate to a thick paste, dry, pulverize, sieve, add appropriate amount of auxiliary materials, mix well, make granules, dry and press into 1000 tablets, and coat with sugar. .

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Abstract

A Chinese medicine for treating the aspirin-resistant cardiovascular disease is prepared from 7 Chinese-medicinal materials including Chuanxiong rhizome, fleece flower root, safflower, red sage root, etc.

Description

technical field [0001] The invention relates to the field of medicine, in particular to the application of a traditional Chinese medicine composition in the preparation of medicines for treating aspirin resistance. Background technique [0002] Aspirin, also known as aspirin or acetylsalicylic acid, has been used clinically for more than 80 years and is an ancient antipyretic and analgesic. In recent years, with the in-depth study of prostaglandins, a new understanding of aspirin has emerged: in addition to traditionally used for antipyretic, analgesic, and anti-inflammatory clinically, it is also used for anti-platelet aggregation and so on. Clinical trials have shown that aspirin is an effective antiplatelet drug for the primary prevention of high-risk patients with cardiovascular and cerebrovascular diseases, and is also effective for the secondary prevention of myocardial infarction and ischemic vascular events. [0003] However, at prese...

Claims

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Application Information

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IPC IPC(8): A61K36/896A61K36/23A61K36/70A61K36/286A61K36/296A61K36/53A61K9/00A61P9/10
Inventor 李永强郑永锋李旭
Owner TIANJIN TASLY PHARMA CO LTD
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