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Food improving blood flow

A blood and fluidity technology, applied in the field of blood fluidity improving compositions, can solve the problem of no research on blood fluidity.

Inactive Publication Date: 2005-09-21
TOYO SHINYAKU KK +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

but no studies have been done on blood fluidity

Method used

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  • Food improving blood flow
  • Food improving blood flow
  • Food improving blood flow

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0081] Embodiment 1: the manufacture of food 1

[0082] Manufacture contains 40% by weight proanthocyanidins (20% by weight OPC), and contains the ethanol extract of the pine bark (trade name: flavandiene Alcohol, Toyo Shinyaku Co., Ltd.), ascorbic acid (Maruzen Pharmaceutical Co., Ltd.), crystalline cellulose, sucrose ester, silicon dioxide, and eggshell calcium tablets (about 200 mg per tablet) (food 1).

Embodiment 2

[0083] Embodiment 2: the manufacture of food 2

[0084] Manufacture the same pine bark ethanol extract (trade name: flavandienol, Toyo Shinyaku Co., Ltd.), crystalline cellulose, sucrose ester, silicon dioxide, and eggshell containing the same weight ratio as in Example 1 described in Table 1 below. Calcium tablets (about 200mg per tablet) (food 2).

Embodiment 3

[0085] Embodiment 3: the manufacture of food 3

[0086] Using Sephadex LH20, under the following conditions, using the same pine bark ethanol extract as in Example 1 (trade name: flavandienol, Toyo Shinyaku Co., Ltd.) to refine proanthocyanidins, prepare proanthocyanidins containing 95.9% by weight Pine bark extract. Tablets (about 200 mg per tablet) containing the weight ratios shown in Table 1 below were produced using the pine bark extract, crystalline cellulose, sucrose esters, silicon dioxide, and eggshell calcium (foodstuff 3).

[0087] Proanthocyanidin Refined

[0088] First, 100 mL of water-swellable MCI gel (manufactured by Mitsubishi Chemical Corporation) was filled in a 30×300 mm column, and washed with 50 mL of purified water. Dissolve 400 mg of the above-mentioned pine bark extract with 8 mL of purified water, make the solution flow through the above-mentioned gel column, and after the proanthocyanidin is adsorbed, dissolve in a gradient with 0-30% (v / v) ethanol...

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Abstract

The composition of the present invention contains proanthocyanidins as active components. When the composition further comprises ascorbic acid or a derivative thereof, the fluidity of blood and effect of protecting blood vessels are further improved. This composition may be a food composition or pharmaceutical composition for improving the blood fluidity. Particularly, this composition is useful as a beverage.

Description

technical field [0001] The present invention relates to a blood fluidity improving composition containing proanthocyanidin as an active ingredient. The composition is a food composition or a pharmaceutical composition for improving blood fluidity. In addition, the present invention also relates to beverage compositions containing proanthocyanidins and ascorbic acid or derivatives thereof. The drink is an effective drink having the effect of improving blood flow. Background technique [0002] In recent years, due to changes in the living environment such as Westernization of diet, lack of exercise, and excessive stress, arteriosclerosis, cerebral thrombosis, and blood and circulatory diseases, as well as hyperlipidemia, diabetes, and other diseases that adversely affect blood circulation have gradually increased. Since these diseases lead to a decrease in the quality of blood flow in microvessels and capillaries, it is pointed out that there is a risk of bringing various ad...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23F3/14A23F3/16A23L1/30A23L33/15A61K31/352A61K31/375A61K36/82A61P9/00A61P43/00
CPCA23V2002/00A23L1/302A61K31/352A61K31/375A23F3/163A23L1/3002A23F3/14A23L33/105A23L33/15A61P43/00A61P9/00A61K2300/00A23V2250/2104A23V2250/708A23V2200/326A23L2/38A23V2250/2132A23V2200/30
Inventor 高垣欣也三井雄史阿部圭一
Owner TOYO SHINYAKU KK
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