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Liver disease treating medicine

A technology for drugs and liver diseases, applied in the field of "Notoginseng compound preparations"

Inactive Publication Date: 2005-06-22
文山壮族苗族自治州三七科学技术研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In summary, there is no report on the compound preparation of Radix Notoginseng and Salvia Miltiorrhiza for the treatment of liver diseases in the prior art

Method used

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  • Liver disease treating medicine
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0120] 1. Extraction of total phenolic acids and effective parts of Panax notoginseng in "Sanqi compound preparation":

[0121] Radix Notoginseng, the former medical material of Danshen (Notoginseng is the dried root of Panax notoginseng (Burk.) F.H.Chen of Araliaceae plant, and Salvia Miltiorrhiza is the dried root and rhizome of Salvia miltiorrhiza Bge. of Labiatae plant) pulverized into coarse powder, According to Sanqi and Salvia miltiorrhiza 2:1 feeding, 6 times of 50% ethanol was refluxed and extracted for 2 hours to extract twice, the extracts were combined, ethanol was recovered, concentrated to 0.5g / ml concentrated solution was acidified to pH 3.5 with (12) HCl, filtered After filtration, the filtrate was applied to the AB-8 macroporous resin column, washed with water until neutral, the eluent was discarded, and eluted with 35% ethanol until FeCl-free 3 Reaction to obtain the total phenolic acid fraction of the "Sanqi Compound Preparation"; continue to elute with 65% ...

Embodiment 2

[0125] According to Example 1 to obtain raw materials, weigh 75.0 grams of effective parts of Panax notoginseng, 75.0 grams of salvianolic acid, 60.0 grams of microcrystalline cellulose, 30.0 grams of micropowder silica gel, and appropriate amount of lactose to make 1000 capsules according to the method of Example 1.

Embodiment 3

[0127] According to Example 1 to obtain raw materials, weigh 150.0 grams of effective parts of Panax notoginseng, 7.5 grams of salvianolic acid, 80.0 grams of microcrystalline cellulose, 40.0 grams of micropowdered silica gel, and appropriate amount of lactose to make 1000 capsules according to the method of Example 1.

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Abstract

The invention provides a liver disease treating medicine, in particular a compound pseudo-ginseng preparation, which is prepared form the effective part of pseudo-ginseng and red sage root total phenolic acid.

Description

Technical field: [0001] The invention relates to a medicine for treating liver diseases, in particular a "notoginseng compound preparation" which is prepared from the effective part of notoginseng and total salvianolic acid as raw materials. Background technique: [0002] Liver fibrosis belongs to the category of blood paralysis in traditional Chinese medicine. Since the middle of the 1970s, research on the prevention and treatment of liver cirrhosis and liver fibrosis with traditional Chinese medicine has been carried out. So far, research has shown that traditional Chinese medicine has obvious advantages in the treatment of liver fibrosis. Its multi-link, multi-level and multi-target Its comprehensive pharmacological effects may be its advantage. In recent years, hepatologists in my country and Japan have conducted a large number of experimental and clinical studies on the treatment of liver fibrosis with traditional Chinese medicine. Fibrosis has both preventive and ther...

Claims

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Application Information

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IPC IPC(8): A61P1/16
Inventor 崔秀明王强蒋云结周家明柯金虎
Owner 文山壮族苗族自治州三七科学技术研究所
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