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Method for preparing taxol micro ball anti-cancer medicine

An anticancer drug, paclitaxel technology, applied in the direction of antineoplastic drugs, drug combinations, antipyretics, etc., can solve problems affecting drug promotion and application, treatment failure, toxic and side effects, etc., to reduce adverse drug reactions and reduce seriousness Toxic and side effects, concentration-enhancing effect

Inactive Publication Date: 2005-01-12
山东居仁生物医药技术研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

This new formulation for making drugs called pacificanes was developed by researchers working with chemotherapy agents that were found effective against certain types of brain cell lines without causing harm or affecting healthy ones. These particles made from this agent have been shown to be able to stop growing lining up small areas inside our body when used alone (like catheters) instead of treatments like surgery or radiation therapies. They are safe even if they don’ve stopped doing anything wrong during their use due to lack of any medications needed.

Problems solved by technology

This patents discusses different types of antimutancies called paclitazanes, including those related to this type of molecule known collectively as tissue factor pathway enzymes involved in inflammation processes. However, these agents may result in harmful side effects when administered over time without being effective at controlling their action. Therefore, finding alternative therapies against them would improve efficacy and reduce potential negative outcomes associated with current therapeutic approaches.

Method used

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Experimental program
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Embodiment approach

[0019] Formula one,

[0020] 3 parts of paclitaxel, 7 parts of slow-release polymer.

[0021] The slow-release polymer uses a mixture of polylactic acid and dichloromethane solution with a concentration of 7%.

[0022] Formula two,

[0023] Paclitaxel 4 parts, slow-release polymer 10 parts.

[0024] The sustained-release polymer was a mixture of lactic acid-glycolic acid copolymer and dichloromethane solution at a concentration of 7%.

[0025] Formula three,

[0026] 3.8 parts of paclitaxel, 9 parts of slow-release polymer.

[0027] The slow-release polymer uses a mixture of polylactic acid and dichloromethane solution with a concentration of 7%.

[0028] Preparation steps:

[0029] Weigh paclitaxel according to the formula ratio under light-shielding conditions and add it to the dichloromethane solution of polylactic acid or lactic acid-glycolic acid copolymer with a concentration of 7%, ultrasonically disperse for 60 seconds to make a suspension, and then slowly dissol...

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Abstract

An anticancer medicine in the form of microball is prepared through proportionally mixing taxusol and slow-releasing polymer in dark condition, stirring, ultrasonic dispersing, slowly dripping it in the aqueous solution of polyglycol, stirring, filtering to collect microballs, washing with distilled water, and drying. It can be mixed with the water for injection.

Description

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Claims

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Application Information

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Owner 山东居仁生物医药技术研究所
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