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Chitosan gelatine polyvinyl alcohol biological hemostatic dressing

A technology of polyvinyl alcohol and hemostatic dressings, applied in the field of medical hemostatic dressings, chitosan gelatin polyvinyl alcohol biological hemostatic dressings, can solve the problems of small elasticity, limited hemostatic effect, poor solubility, etc. Ease of absorption and high adsorption capacity

Inactive Publication Date: 2004-12-15
张淑荣
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, hemostatic dressings with chitin and chitosan as the main components have been developed successively. Materials such as gelatin sponges are mostly used, and there are also hemostatic materials with chitin and gelatin as the main components. , traction and hemostatic effects are not ideal enough
Simply using chitosan and gelatin as a hemostatic material has been reported in the literature, but due to its limited hemostatic effect and poor solubility of chitosan, it only accounts for about 2% of the hemostatic material, thereby affecting the hemostatic effect, and the elasticity too small to use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] Dissolve 20g of chitosan in 600ml of 0.2% concentration of acetic acid solution, take 20g of polyvinyl alcohol and add boiling water to dissolve, heat and melt 15g of gelatin, add water to dissolve 15g of glycerin, combine the above solutions, fully stir to make them uniform, freeze-dry, cut and divide Packed and Co60 sterilized to make a hemostatic dressing.

Embodiment 2

[0060]Dissolve 40g of chitosan in 1000ml of 1.2% concentration of acetic acid solution, take 55g of polyvinyl alcohol and add boiling water to dissolve, heat and melt 30g of gelatin, add water to dissolve 40g of glycerin, combine the above solutions, fully stir to make uniform, freeze-dry, cut and divide Pack and sterilize to make a hemostatic dressing.

Embodiment 3

[0062] Dissolve 60g of chitosan in 800ml of 0.8% acetic acid solution, add 40g of polyvinyl alcohol to dissolve in boiling water, heat to melt 10g of gelatin, add 10g of glycerin to dissolve in water, combine the above solutions, stir well to make them uniform, freeze-dry, cut and pack , Co60 sterilization made hemostatic dressing.

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PUM

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Abstract

The biological chitosan-gelatin-polyvinyl alcohol hemostatic dressing is compounded with chitosan, gelatin, polyvinyl alcohol and glycerin, and is prepared into hemostatic cotton, spray and other externally applied medicine forms via conventional production process. The present invention has high adsorption amount, maintained amount, no toxicity, easy absorption by body and high hemostatic function and is superior to available hemostatic dressing.

Description

Technical field: [0001] The present invention relates to the improvement of producing hemostatic dressing with chitosan as the main raw material, and further provides a chitosan gelatin polyvinyl alcohol biological hemostatic dressing, which belongs to medical hemostatic dressing [0002] technology field. Background technique [0003] Chitosan (chiosail.cs), also known as chitosan, is the main derivative of chitin. Its preparation is simple, its source is abundant, its price is cheap, and it is easy to be biodegraded into non-toxic small molecule compound glucosamine, so it is more and more popular. people's attention. In recent years, hemostatic dressings with chitin and chitosan as the main components have been developed successively. Materials such as gelatin sponges are mostly used, and there are also hemostatic materials with chitin and gelatin as the main components. , traction and hemostatic effects are not ideal enough. Simply using chitosan and gelatin as a hemo...

Claims

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Application Information

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IPC IPC(8): A61L15/32
Inventor 张淑荣
Owner 张淑荣
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