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Starch hydrogel

A hydrogel and starch technology, applied in the field of radiation cross-linked starch hydrogel, can solve the problems of difficult removal, discomfort, and inability to prevent wound drying.

Inactive Publication Date: 2004-03-10
MALAYSIAN INST FOR NUCLEAR TECH RES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

They have the disadvantage of not being able to prevent dryness of the wound, as a result dry tissue forms over the wound, they allow infectious agents such as bacteria and fungi to gain access to the wound
They stick to the wound, making them difficult to remove, and also remove new growth tissue that has become attached to them, so redressing the wound can cause pain and discomfort for the patient

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] A series of hydrogels were prepared using 7.5% (a) sago starch; (b) tapioca starch or (c) corn starch, 7.5% polyvinylpyrrolidone, 7.5% polyvinyl alcohol and 3.0% carboxymethylcellulose.

[0023] The gel was prepared by dissolving the individual components in distilled water to form a solution, mixing the solution at a temperature of about 90°C with gentle stirring until a clear semi-gel solution was obtained, and applying electron beam irradiation at a dose of 25 kGy.

[0024] The properties of the hydrogels are listed in Table 1.

[0025] starch

Gel strength (MPa)

Elongation (%)

Water absorption (%)

west valley

2.33×10 -2

296

5516

cassava

1.47×10 -2

300

6012

corn

2.28×10 -2

276

4466

[0026] A series of hydrogels were prepared using 7.5% sago starch, 7.5% polyvinylpyrrolidone, 7.5% polyvinyl alcohol and 3.0% carboxymethylcellulose.

[0027] In ...

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PUM

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Abstract

The hydrogel forming composition contains up to 10 wt.% of the starch, up to 5 to 7.5 wt.% of polyvinylpyrrolidon, up to 5 to 10 wt.% of polyvinyl alcohol, up to 1% to 3 wt.% of water-soluble cellulose and water. The hydrogel is prepared by exposing a half-gelled material made of the composition to an electron beam or a [gamma]-ray to the extent that the total beam absorption amounts to 5 to 50 kGy.

Description

technical field [0001] The present invention relates to starch hydrogels, more particularly, the present invention relates to radiation crosslinked starch hydrogels, which are especially suitable for medical and surgical applications, for example as dressings for wounds such as burns, throat ulcers and bedsores, as Materials in contact with lenses and artificial cartilage and drug delivery systems. Background technique [0002] Gauze wound dressings have been used for many years. They have the disadvantage of not being able to prevent dryness of the wound, as a result dry tissue is formed on the wound, and they allow access of infectious agents such as bacteria and fungi to the wound. They adhere to the wound, making their removal difficult, and also remove new growth tissue that has become attached to them, so that redressing the wound can cause pain and discomfort to the patient. [0003] In the search for alternative gauze dressings, various biological or biosynthetic m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/58A61L15/28C08J3/28C08L1/26C08L3/02C08L29/04C08L39/06
Inventor K·哈希姆K·Z·M·达赫兰K·巴哈里N·莫西德N·A·阿比丁
Owner MALAYSIAN INST FOR NUCLEAR TECH RES
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