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Medicine for curing tumor and its preparation method

A drug and tumor technology, applied in anti-tumor drugs, drug combinations, pharmaceutical formulations, etc., to protect liver and kidney functions, reduce toxic side effects, and improve clinical symptoms

Inactive Publication Date: 2002-09-04
BEIJING CANCER HOSPITAL PEKING UNIV CANCER HOSPITAL +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned drugs have only been tested on animals, and the tumor inhibition rate is more than 30%, and the drug effect cannot enter the cells through the diesterase signaling pathway.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0103] Weigh raw materials according to the following ratio (kg)

[0104] Astragalus 15 Angelica 8 Baiying 20 Solanum nigrum 12

[0105] Salvia 5 Barbata 20 Snakeberry 10 Turmeric 9

[0106] The preparation method is as follows:

[0107] First take astragalus, angelica, nightshade, turmeric, banzhilian, baiying, and snakeberry, add water to decoct, combine the decoction, filter, and concentrate the filtrate under reduced pressure at 45°C; The concentration of ethanol used for the second time is 92-95%, and the concentration of ethanol used for the second time is 50-55%), filter, reclaim ethanol, combine the extract, filter the residue and extract with water, filter, filtrate and ethanol extract Concentrate under reduced pressure at 45°C; after the concentrates are combined, spray dry at an inlet temperature of 150°C and rotate 10,000 times per minute to obtain a dry product, add an appropriate amount of excipients (lactose, magnesium stearate, mixed Evenly carry out pre-tab...

Embodiment 2

[0108] Weigh raw materials according to the following ratio (kg)

[0109] Astragalus 15 Angelica 6 Baiying 18 Solanum nigrum 20

[0110] Salvia 5 Barbata 15 Snakeberry 12 Turmeric 6

[0111] The preparation method is as follows:

[0112] First take astragalus, angelica, nightshade, turmeric, banzhilian, baiying, and snakeberry, add water to decoct, combine the decoction, filter, and concentrate the filtrate under reduced pressure to form a thick paste with a relative density of 1.2-1.3 (50-65°C) , dried in vacuum to obtain a dry paste. Radix salviae ethanol is refluxed twice (wherein the concentration of ethanol used for the first time is 92~96%, the concentration of used ethanol for the second time is 45~50%), filter, recover ethanol, combine extract, filter the residue with water Extraction, filtration, the filtrate and the alcohol extract are concentrated under reduced pressure to form a thick paste with a relative density of 1.1-1.3 (50-65°C), and vacuum-dried to obtain...

Embodiment 3

[0114] Weigh raw materials according to the following ratio (kg)

[0115] Astragalus 20 Angelica 10 Baiying 18 Solanum nigrum 15

[0116] Salvia 8 Barbata 15 Snakeberry 10 Turmeric 8

[0117] The preparation method is as follows:

[0118] First take astragalus, angelica, nightshade, turmeric, barbata, bletilla, and snakeberry, add water to decoct, combine the decoction, filter, and concentrate the filtrate under reduced pressure to form a thick paste with a relative density of 1.1-1.3 (50-65°C). ), vacuum-dried to obtain a dry paste. Radix salviae ethanol is refluxed twice (wherein the concentration of ethanol used for the first time is 95%, and the concentration of ethanol used for the second time is 50%), filter, reclaim ethanol, combine extracts, filter the remainder to extract with water, filter , the filtrate and the alcohol extract were concentrated under reduced pressure into a thick paste (55-65° C.) with a relative density of 1.1 to 1.3, and dried in vacuum to obta...

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PUM

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Abstract

The medicine for curing tumor is made up by using 8 Chinese medicinal materials of astragalus root, Chinese angelica root, climbing nightshade, salvia root, bearded scutellaria, snake strawberry and curcuma tuber as raw material through the processes of extraction respectively by using water and ethyl alcohol as solvent, concentration, drying, pulverizing, and making it into power preparation, granules preparation, tablet preparation, capsule preparation, liquor or block preparation.

Description

field of invention [0001] The invention relates to a drug for treating tumors. Specifically, it is a Chinese patent medicine prepared from Chinese herbal medicines. The invention also relates to a preparation method of the medicine. Background technique [0002] Malignant tumor is a malignant disease that seriously threatens human health. Its morbidity and mortality are increasing day by day, and it is very harmful. The World Health Organization report in 1998 pointed out that in 1997, there were 9.24 million new cancer patients and 6.235 million deaths in the world. It is predicted that there will be 20 million new cancer cases and 12 million deaths in 2020. The incidence of cancer in our country is also showing a sharp upward trend year by year, reaching 1.6 million in 2000, and the death toll has reached 1.3 million. The death rate of cancer ranks second in the world. At present, the common methods for treating tumors at home and abroad, such as surgery, radiotherapy...

Claims

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Application Information

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IPC IPC(8): A61P35/00
Inventor 梁云燕穆育新王代树
Owner BEIJING CANCER HOSPITAL PEKING UNIV CANCER HOSPITAL
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